ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation by Jiaxing Zhang, Jiaxing Zhang, Gang Wang, Jie Liu, Futian Tang, Song Wang, Yumin Li, Yumin Li

“…However, its role across different cancer types is not well understood.MethodsUtilizing multi-omics data, we comprehensively evaluated ITGA4’s expression, clinical relevance, diagnostic and prognostic value, functions, mutations, and methylation status, along with its impact on immunity, mismatch repair (MMR), heterogeneity, stemness, immunotherapy responsiveness, and drug resistance in pan-cancer, with partial validation in gastric cancer (GC) using transcriptomic analysis, single-cell data, western blot (WB), wound-healing assay, flow cytometry and immunohistochemistry (IHC). …”
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Diversity of performance patterns in dairy goats: multi-scale analysis of the lactation curves of milk yield, body condition score and body weight by Gafsi, Nicolas, Martin, Olivier, Bidan, Fabrice, Grimard, Bénédicte, Puillet, Laurence

“…Principal component analysis was performed on the MY, BW and BCS indicators separately, and clusters of phenotypic curves identified. …”
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Kinesiophobia and its associated factors among patients after transcatheter aortic valve replacement: a cross-sectional study based on latent profile analysis by Zhiyun Shen, Dandan Geng, Chenxu Huang, Daxin Zhou, Xiaohua Xu, Ying Lin, Yuxia Zhang

“…Latent profile analysis (LPA) was performed to classify patients into latent subgroups based on their levels of kinesiophobia. …”
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Experimental validation of cuproptosis-associated molecular signatures and their immunological implications in pulmonary tuberculosis by Xiaofang Liu, Xiaofang Liu, Qianqian Ma, Zhiming Li, Yong Xue, Jie Mi, Yuxi Li, Chunfeng Bai, Donglin Guo, Yinping Liu, Yan Liang, Jianqin Liang, Xueqiong Wu

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Study on the Structural Behaviour of the Topside Modules of FPSO under the Forces Exerted on the Ship Hull by M. Saleh, R. Amirabadi, A. Kheiri

“…Modeling of the studied module was executed by SACS software and the effect of support using neoprene in the function of the module’s members was studied. The members of this module are divided into two general areas: the first area includes fulcrum members under the main deck of module and the second area includes installed members on the main deck and equipment of the module which is investigated in three directions; longitudinal, transverse and vertical. …”
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Defense training of border villages with passive defense approach; case study: border villages of Piranshahr by Mohammad Hassan Nami

“…The spatial findings were analyzed using GIS, the Analysis Hierarchy Process (AHP), and fuzzy logic. …”
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Efficient Solution of Fokker–Planck Equations in Two Dimensions by Donald Michael McFarland, Fei Ye, Chao Zong, Rui Zhu, Tao Han, Hangyu Fu, Lawrence A. Bergman, Huancai Lu

“…Finite element analysis (FEA) of the Fokker–Planck equation governing the nonstationary joint probability density function of the responses of a dynamical system produces a large set of ordinary differential equations, and computations become impractical for systems with as few as four states. …”
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Quality of ejaculate of male patients with type 2 diabetes mellitus (DM), vaccinated with GamCovidVac (Sputnik V) by D. I. Esaulenko, R. R. Rozhivanov, V. V. Shishkina

“…Though a few patients reported general somatic side effects after the vaccination, there have been no statistically significant deviations in sperm count, viability, function and morphology. …”
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LePB-SA4RE: A Lexicon-Enhanced and Prompt-Tuning BERT Model for Evolving Requirements Elicitation from App Reviews by Zhiquan An, Hongyan Wan, Teng Xiong, Bangchao Wang

“…Pre-trained language models with fine-tuning (FT) have achieved notable success in aspect-based sentiment analysis (ABSA) for automatic requirements elicitation from app reviews. …”
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PIGR predicts good clinical outcomes and plays a tumor suppressor role in the development of breast cancer by Tengfei Jiang, Zhi Sun, Zhi Sun, Ke Dong, Qian Pu, Haidong Gao, Haidong Gao, Yanrong Lv, Peng Li, Guanghui Zhao, Guanghui Zhao

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Vitamin D deficiency, fatigue, and persistent cough as independent predictors of depressive symptoms in sarcoidosis patients by Gvozdenovic Branislav S., Mihailovic-Vucinic Violeta, Vukovic Mira, Omcikus Maja, Cvejic Jelena, Belic Slobodan, Jankovic Jelena, Đurđevic Natasa, Stjepanovic Mihailo

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Symptomatic and cognitive effects of D-amino acid oxidase inhibitors in patients with schizophrenia: a meta-analysis of double-blind randomized controlled trials by Chun-Hung Chang, Yu-Der Hsia, Wen-Chun Liu, Jia-Hau Lee, Chieh-Hsin Lin, Hsien-Yuan Lane

“…The Positive and Negative Syndrome Scale (PANSS) was used in all studies to evaluate clinical symptoms, with four studies also assessed cognitive function. This analysis highlighted that DAOI surpassed the comparator in reducing the scores of PANSS total (SMD = −0.270, P = 0.035), PANSS positive (SMD = −0.399, P = 0.022), PANSS negative (SMD = −0.171, P = 0.026), and PANSS general psychopathology (SMD = −0.180, P = 0.019). …”
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The Effect of Comorbidities on Asthma-Related Outcomes Over a Two-Year Period: A Prospective Analysis of Swiss Severe Asthma Registry (SSAR) by Jaun F, Kanagarasa M, Boesing M, Lüthi-Corridori G, Bridevaux PO, Charbonnier F, Clarenbach CF, Gianella P, Jochmann A, Kern L, Pavlov N, Rothe T, Latshang TD, Von Garnier C, Leuppi JD

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3D-printed PCL scaffolds combined with injectable sodium alginate/magnesium-doped mesoporous bioactive glass nanosphere hydrogel for meniscus regeneration: In vitro, In vivo, and m... by Hao Li, Yongkang Yang, Tianze Gao, Runmeng Li, Chao Wang, Xue Wang, Tianyuan Zhao, Qinyu Tian, Zhixing Zhang, Ruiyang Zhang, Quanyi Guo, Zhiguo Yuan, Peifu Tang

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Correlates and determinants of physical activity among older adults of lower versus higher socio-economic status: a systematic review and meta-analysis by Olivia S. Malkowski, Jessica Harvey, Nick P. Townsend, Mark J. Kelson, Charlie E. M. Foster, Max J. Western, Physical Activity Inequalities in Later Life consortium

“…Of the exposures positively associated with physical activity, physical function, social participation, and perception of general health had the largest effect sizes (standardised mean difference [SMD] range = 0.53–0.81; I2 range = 54.81–91.00%). …”
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Designing a supply chain resilience assessment model with the approach of NDEA(case of study: government hospitals of Yazd province) by Mohsen Shafiei Nikabadi, Fereshteh Bahrami

“…Determining the effective and ineffective hospitals, and finally, according to the results of the data coverage analysis, the sensitivity analysis of the data has been done. …”
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A first principle investigation to explore the effect of Zr-site Ti doping on structural, electronic, optical, and mechanical properties of BaZrO3 by Apon Kumar Datta, M. Khalid Hossain, M. S. Revathy, M. Sudhakara Reddy, Abhayveer Singh, S. Radhika, Satish Choudhury, Ankur Singh Bisht, Abdullah M. S. Alhuthali, Magda H. Abdellattif, R. Balachandran, Rajesh Haldhar

“…This investigation delves into the comprehensive assessment of structural, electronic, optical, mechanical, and thermodynamic properties in Ti-doped BaZrO3 (BaZr1-xTixO3 where x = 0,0.25, 0.5, 0.75) through the application of Density Functional Theory (DFT) employing the Generalized Gradient Approximation (GGA) and Perdew-Burke-Ernzerhof (PBE) exchange–correlation function. …”
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Effects of combination antihypertensive therapy on intracardiac hemodynamics and blood vessels in patients with coronary heart disease, post-infarction cardiosclerosis and arterial... by M. M. Dolzhenko, S. A. Bondarchuk, L. Ye. Lobach

“…When analyzing the indicators of diastolic function in the second group, a highly significant (p < 0.05) decrease in E/A, E/E’, IO of the LA has been revealed; data analysis on the morphofunctional state indicators of the extracranial arteries has shown a CIM reduction and a decrease in PSV and RI. …”
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Analysis Method for the Pouring Stage of Concrete-Filled Steel Tube (CFST) Arch Bridges Considering Time-Varying Heat of Hydration and Elastic Modulus by Mengsheng Yu, Xinyu Yao, Kaizhong Xie, Tianzhi Hao, Xirui Wang

“…Most of the existing models focus on static self-weight analysis but generally ignore the above-mentioned dynamic heat–force interaction, resulting in significant prediction deviations. …”
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Utilization of Transthoracic Echocardiography Is Associated with a Decreased 6-month Readmission Rate in Hospitalized Heart Failure: A Propensity Score-matched Analysis by Zhiqing Fu, Shan Li, Xiaoning Zhao, Qiang Wang

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