Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy by Dongming Li, Donghui Cao, Yangyu Zhang, Xinyi Yu, Yanhua Wu, Zhifang Jia, Jing Jiang, Xueyuan Cao

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Trauma outcomes differences in females: a prospective analysis of 76 000 trauma patients in the Asia-Pacific region and the contributing factors by Mohamad Iqhbal Bin Kunji Mohamad, Sabariah Faizah Jamaluddin, Norhaiza Ahmad, Arifah Bahar, Zarina Mohd Khalid, Nuraina Aqilah Binti Mohd Zaki, Nurul Azlean Norzan, Sang Do Shin, Goh E. Shaun, Wen-Chu Chiang, Kentaro Kajino, Kyoung Jun Song, Do Ngoc Son

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rcprd: An R package to simplify the extraction and processing of Clinical Practice Research Datalink (CPRD) data, and create analysis-ready datasets. by Alexander Pate, Rosa Parisi, Evangelos Kontopantelis, Matthew Sperrin

“…Functions are available to extract common variable types (e.g., history of a condition, or time until an event occurs, relative to an index date), and more general functions for database queries, allowing users to define their own variables for extraction. …”
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Analysis of Surface Roughness and Machine Learning-Based Modeling in Dry Turning of Super Duplex Stainless Steel Using Textured Tools by Shailendra Pawanr, Kapil Gupta

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MicrocrackAttentionNext: Advancing Microcrack Detection in Wave Field Analysis Using Deep Neural Networks Through Feature Visualization by Fatahlla Moreh, Yusuf Hasan, Bilal Zahid Hussain, Mohammad Ammar, Frank Wuttke, Sven Tomforde

“…The impact of various activation and loss functions are examined through feature space visualisation using the manifold discovery and analysis (MDA) algorithm. …”
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NMDA receptor inhibition increases, synchronizes, and stabilizes the collective pancreatic beta cell activity: Insights through multilayer network analysis. by Marko Šterk, Lidija Križančić Bombek, Maša Skelin Klemen, Marjan Slak Rupnik, Marko Marhl, Andraž Stožer, Marko Gosak

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Effect of exercise intervention on quality of life and exercise capacity in patients with atrial fibrillation: a systematic review and network meta-analysis by Yaya Xi, Yinxue Zhang, Leyao Han, Meishan Zhang, Yunyun Liu, Jingying Xiong, Yingqiao Wang, Weiping Li, Feng Bai, Minmin Cai, Xinman Dou, Xinman Dou, Xinglei Wang, Xinglei Wang

“…Additionally, aerobic exercise (AE) was the most effective in increasing vitality (MD = 7.73, 95% Crl: 6.40 to 9.07, SUCRA = 88.07%).ConclusionThis network meta-analysis found that MB had superior effects on general health and exercise capacity. …”
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Demographics and Clinical Characteristics among Patients with Distinct Psychosocial Burden Profiles Related to Vitiligo: Results of a Latent Class Analysis by Kent A. Hanson, Khaled Ezzedine, Jenny Austin, Peter Anderson, Simran Marwaha, Samantha K. Kurosky, Roni Adiri, James Piercy, Ernest H. Law

“…This study aimed to classify patients on the basis of the impact of vitiligo on emotional/psychological and social functioning and describe patient characteristics and patient-reported outcome (PRO) responses for each profile. …”
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Geospatial Spatiotemporal Analysis of Tourism Facility Attractiveness and Tourism Vitality in Historic Districts: A Case Study of Suzhou Old City by Mi Zhou, Jianqiang Yang

“…The findings reveal a generally positive correlation between tourism attractiveness and tourism vitality. …”
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Using Relational Biology with Loop Analysis to Study the North Atlantic Biological Carbon Pump in a ‘Hybrid’ Non-Algorithmic Manner by Patricia A. Lane

“…It is suggested that the ecosystem level should replace the cellular and organismic levels as the main system unit in biology and evolution since all life exists and evolves with full functional potential in ecosystem networks and not laboratory test tubes. …”
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Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. by Karen Kapur, Toby Johnson, Noam D Beckmann, Joban Sehmi, Toshiko Tanaka, Zoltán Kutalik, Unnur Styrkarsdottir, Weihua Zhang, Diana Marek, Daniel F Gudbjartsson, Yuri Milaneschi, Hilma Holm, Angelo Diiorio, Dawn Waterworth, Yun Li, Andrew B Singleton, Unnur S Bjornsdottir, Gunnar Sigurdsson, Dena G Hernandez, Ranil Desilva, Paul Elliott, Gudmundur I Eyjolfsson, Jack M Guralnik, James Scott, Unnur Thorsteinsdottir, Stefania Bandinelli, John Chambers, Kari Stefansson, Gérard Waeber, Luigi Ferrucci, Jaspal S Kooner, Vincent Mooser, Peter Vollenweider, Jacques S Beckmann, Murielle Bochud, Sven Bergmann

“…This genome-wide meta-analysis shows that common CASR variants modulate serum calcium levels in the adult general population, which confirms previous results in some candidate gene studies of the CASR locus. …”
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Descriptive and temporal analysis of the mortality rate and average hospital stay due to burns and corrosion in the elderly in Brazil between 2010 and 2019 by Arthur Antunes Coimbra Pinheiro Pacífico, Ester Saraiva Carvalho Feitosa, Anna Letícia Silveira Parnaíba, Pedro Lucena de Aquino, Amanda de Andrade Cavalcante, Thalia de Souza Bezerra, Leandro Dantas Rolim, Samy Lima Carneiro

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Fracture toughness and microstructural analysis of rotary friction welded S355J2 and SS316L steels for critical applications by Rajkumar Das, Giribaskar Sivaswamy, Himanshu Lalvani, Ajit Pal Singh

“…Dissimilar metal welding is seeing growing adoption across industries to enhance structural functionality and efficiency. Achieving high-quality, defect-free dissimilar weld joints requires a comprehensive understanding of the interrelationships between the welding-induced microstructural changes and the material's performance characteristics, particularly its fracture-related properties. …”
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Quantitative relationships between elastic modulus of rod and biomechanical properties of transforaminal lumbar interbody fusion: a finite element analysis by Jie Li, Zengfeng Du, Shuai Cao, Teng Lu, Zhongwei Sun, Hongyu Wei, Haopeng Li, Ting Zhang

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Analysis of Spatiotemporal Variation and Driving Forces of Vegetation Net Primary Productivity in the North China Plain over the Past Two Decades by Mingxuan Yi, Dongming Zhang, Zhiyuan An, Kuan Li, Liwen Shang, Kelin Sui

“…The net primary productivity (NPP) of vegetation—a critical component of ecosystem carbon cycling and a key indicator of the quality and functionality of ecosystems—is jointly influenced by natural and anthropogenic factors. …”
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Multi-ancestry meta-analysis of genome-wide association studies discovers 67 new loci associated with chronic back pain by Ian B. Stanaway, Pradeep Suri, Niloofar Afari, Daniel Dochtermann, Armand Gerstenberger, Saiju Pyarajan, Eric J. Roseen, Million Veteran Program, Marianna Gasperi

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Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans. by Roz Laing, Martin Hunt, Anna V Protasio, Gary Saunders, Karen Mungall, Steven Laing, Frank Jackson, Michael Quail, Robin Beech, Matthew Berriman, John S Gilleard

“…This group of parasites has the closest phylogenetic relationship with the model organism Caenorhabditis elegans, making comparative analysis a potentially powerful tool for genome annotation and functional studies. …”
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Falls prevention interventions for community-dwelling older adults: systematic review and meta-analysis of benefits, harms, and patient values and preferences by Jennifer Pillay, Lindsay A. Gaudet, Sabrina Saba, Ben Vandermeer, Ashiqur Rahman Ashiq, Aireen Wingert, Lisa Hartling

“…Fractures are probably more important than either falls (0.09 over 12 months) or functional status (0.12). Functional status may be somewhat more important than falls. …”
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The greener, the richer, the happier?——Spatial distribution and coupling analysis of urban green space and residents’ emotion based on social media data by Zexun Li, Lihui Hu, Alin Lin, Jiarui Chen, Yue Xu

“…It has also discovered that enhancing the quality and functionality of green spaces can boost urban well-being, offering valuable guidance to planners in the context of park city.…”
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Integrated Meta-Analysis Identifies Keratin Family Genes and Associated Genes as Key Biomarkers and Therapeutic Targets in Metastatic Cutaneous Melanoma by Sumaila Abubakari, Yeşim Aktürk Dizman, Filiz Karaman

“…Thereafter, an integrated meta-analysis and functional enrichment analysis of the DEGs were performed to evaluate the molecular mechanisms involved in melanoma metastasis, such as immune cell deconvolution and protein-protein interaction (PPI) network construction. …”
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