Comprehensive Splice Pattern Analysis for Previously Reported OCRL Splicing Variants and Their Phenotypic Contributions by Rini Rossanti, Eri Okada, Nana Sakakibara, Ryota Suzuki, Yuta Inoki, Yuta Ichikawa, Yu Tanaka, Hideaki Kitakado, Chika Ueda, Atsushi Kondo, Yuya Aoto, China Nagano, Tomoko Horinouchi, Tomohiko Yamamura, Shingo Ishimori, Kandai Nozu

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Analysis on related risk factors for cardiocerebral vascular diseases in patients with diabetic kidney disease by ZHANG Zhi-xu, GAO Ai-qing, RAO Xiao-pang

“…Objective To investigate the epidemiology and related risk factors for cardiocerebral vascular diseases in patients with diabetic kidney diseases（DKD）.Methods A total of 800 patients with DKD hospitalized in Chengyang District People’s Hospital of Qingdao from January 2016 to December 2017 were enrolled in this study.Based on complications of cardiocerebral vascular diseases, the patients were divided into the cardiocerebral vascular disease group（n=558） and group without cardiocerebral vascular diseases（n=242）.The general information,including gender,age,body mass,height,systolic blood pressure（SBP）, diastolic blood pressure（DBP）,drinking history and smoking history, and laboratory test indicators, including fasting blood glucose（FBG）, glycosylated hemoglobin（HbA1 C）, liver and kidney functions, total cholesterol（TCH）, triglyceride（TG）, low density lipoprotein cholesterol（LDL-C）, high density lipoprotein cholesterol（HDL-C）, Lipoprotein A（Apoa）,parathyroid hormone（PTH）, C-reactive protein（CRP）, hemoglobin（Hb）, white blood cells（WBC）, brain natriuretic peptide（BNP）, urinary microalbumin/urinary creatinine ratio（UACR） and serum β₂-microglobulin（β₂-MG）were detected. …”
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Transcriptome analysis reveals the mechanism of mixed oligosaccharides in the response of rice seedlings to abiotic stresses by Yanan Xu, Yanan Xu, Yigang Yang, Yeran Bai, Makoto Saito, Wei Han, Yuanpei Zhang, Guohua Lv, Jiqing Song, Wenbo Bai

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Spatial Influence Analysis of Traffic Safety in Diverging Areas between Freeway Segments and Off Ramps by Cuiping Zhang, Xuedong Yan, Meiwu An, Hui Zhao

“…Data from a geocoded GIS crash database for Colorado Springs metropolitan area was used; the statistically significant factors associated with crash frequency were examined for the spatial influence of freeway diverging segments. Also, the generalized linear models with negative binomial link function were applied to predict the crash frequency for freeway diverging segments and off ramps based on the influential area. …”
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Carotid Intima-Media Thickness and Visit-to-Visit HbA1c Variability Predict Progression of Chronic Kidney Disease in Type 2 Diabetic Patients with Preserved Kidney Function by Akiko Takenouchi, Ayaka Tsuboi, Miki Kurata, Keisuke Fukuo, Tsutomu Kazumi

“…Subclinical atherosclerosis and long-term glycemic variability have been reported to predict incident chronic kidney disease (CKD) in the general population. However, these associations have not been investigated in patients with type 2 diabetes with preserved kidney function. …”
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Quantitative Analysis of Fish Morphology Through Landmark and Outline-based Geometric Morphometrics with Free Software by Du Luo

“…This study presents a comprehensive workflow for conducting geometric morphometric analysis of fish morphology. The step-by-step manual provides detailed instructions for using popular free software, such as the TPS series, MorphoJ, ImageJ, and R, to carry out generalized Procrustes analysis (GPA), principal component analysis (PCA), discriminant function analysis (DFA), canonical variate analysis (CVA), mean shape analysis, and thin plate spline analysis (TPS). …”
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Using functional near-infrared spectroscopy to study effects of virtual reality intervention for adolescents with depression in a clinical setting in China: study protocol for a pr... by Yan Zhang, Lijun Wang, Dongsheng Zhou, Xiaofang Ye, Kunqiang Yu, Shaochang Wu, Shiqiao Lv, Linhui Liu, Xiuxiu Zheng, Ruomei Jin, Guoqing Min

“…In addition, patients randomised to VR treatment group (n=33) will complete three 20 min VR sessions including attention, executive function and relaxation training per week. Moreover, 33 healthy adolescents will be recruited as the general population. …”
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Constructing psychometric measurement of a past supervised experience scale with educational roles to investigate the relationship between being instructed, being supported, and be... by Yu-Chih Lin, Ling-Chun Ou

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Multivariate evaluation method for the detection of pest infestations on plants via VOC analysis using gas chromatography mass spectrometry by Sarah Vermeeren, Markus Witzler, Ramona Makarow, Carsten Engelhard, Peter Kaul

“…For this reason, a multivariate evaluation method based on a self-written Python script, using principal component analysis (PCA) and linear discriminant analysis (LDA), was developed and tested for functionality using a dataset, which has been evaluated manually and has identified five specific markers (2,4-dimethyl-1-heptene, 3-carene, $$\alpha$$ -longipinene, cyclosativene, and copaene) for Anoplophora glabripennis (ALB) infestation on Acer trees. …”
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Cognitive function and associations with demographic, socioeconomic, health and behavioural factors among older adult men and women in rural Bangladesh: a population-based cross-se... by Edward Fottrell, Harry Costello, Naveed Ahmed, Carina King, Sanjit Kumer Shaha, Tasmin Nahar, Malini Pires, Andrew Copas, Hassan Haghparast-Bidgoli, Joanna Morrison, Abdul Kuddus, Kishwar Azad

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A Comparative Analysis of Three Data Fusion Methods and Construction of the Fusion Method Selection Paradigm by Ziqi Liu, Ziqiao Yin, Zhilong Mi, Binghui Guo, Zhiming Zheng

“…In this paper, we present a theoretical analysis of early fusion, late fusion, and gradual fusion methods. …”
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Free Vibration Analysis of Moderately Thick Rectangular Plates with Variable Thickness and Arbitrary Boundary Conditions by Dongyan Shi, Qingshan Wang, Xianjie Shi, Fuzhen Pang

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Analysis of the Endocrine Responses to Anti-Diabetes Drugs: An Issue of Elevated Plasma Renin Concentration in Sodium-Glucose Co-Transporter 2 Inhibitor by Lin CW, Hung SY, Chen IW

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Cathepsin H increases the risk of diabetic retinopathy: evidence from Mendelian randomization and bioinformatic analysis by Xiudao Song, Jin Ma, Ting Zou, Rong Xin Lu, Wei Ji, Fei Huang, Meiqi Yin

“…To further characterize the biological relevance of identified cathepsins, we conducted multi-omics investigations including gene set enrichment analysis, CIBERSORT, single-cell RNA sequencing analysis to explore the expression level, immune infiltration and biological function of identified cathepsins. …”
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The Effectiveness of Computerized Cognitive Training in Patients With Poststroke Cognitive Impairment: Systematic Review and Meta-Analysis by Min Gao, Lu Huang, Jiang Yi, Tianqi Zhang, Guangyao Zhu, Qi Zhang, Jiaxiao Tian, Rongxuan Zhao, Xiaoqin Duan, Zhongliang Liu

“…ResultsA total of 19 trials were included in the meta-analysis (n=875 participants). The findings provided moderate- to high-quality evidence indicating that CCT significantly enhances general cognitive function (15 trials, standardized mean difference [SMD]= 0.46, 95% CI 0.21-0.71; P<.001, I2=60%), attention (11 trials, SMD=–0.45, 95% CI –0.64 to –0.25, P<.001, I2=0%), executive function (6 trials, SMD=0.39, 95% CI 0.12-0.67; P=.01, I2=0%), and quality of life of PSCI patients (9 trials, SMD=0.34, 95% CI 0.15-0.53; P<.001, I2=6%). …”
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Classical Gasses with Singular Densities by Luca Di Persio, Yuri Kondratiev, Viktorya Vardanyan

“…These generalized functions provide deeper insights into the correlations between particle positions and velocities, expanding the range of analysis to systems with singular velocity distributions. …”
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Effect of non-invasive brain stimulation on post-stroke cognitive impairment: a meta-analysis by Jing Zhao, Qian Meng, Shuo Qi, Hongfei Zhao, Ling Xia

“…The extracted study data were entered into STATA 12.0 software for statistical analysis.ResultsThis meta-analysis provides evidence that both rTMS and tDCS have a positive impact on general cognitive function in PSCI patients [immediate effect of rTMS: standard mean difference (SMD) = 2.58, 95% confidence interval (CI) = 1.44 to 3.71; long-term effect of rTMS: SMD = 2.33, 95% CI = 0.87–3.78; immediate effect of tDCS: SMD = 2.22, 95% CI = 1.31–3.12]. …”
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The relevance of creating a new combination drug for the treatment of cognitive disorders by L. I. Kucherenko, V. H. Slobodianyk

“…Constant stress, loss of loved ones, forced displacement and a general sense of danger significantly affect cognitive functions, such as memory, concentration and planning ability. …”
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Smartphone Screen Time Characteristics in People With Suicidal Thoughts: Retrospective Observational Data Analysis Study by Marta Karas, Debbie Huang, Zachary Clement, Alexander J Millner, Evan M Kleiman, Kate H Bentley, Kelly L Zuromski, Rebecca G Fortgang, Dylan DeMarco, Adam Haim, Abigail Donovan, Ralph J Buonopane, Suzanne A Bird, Jordan W Smoller, Matthew K Nock, Jukka-Pekka Onnela

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Calculation of Derivatives in the Lp Spaces where 1 ≤ p ≤ ∞ by Anatoly Nikolaevich Morozov

“…It is well known in functional analysis that construction of \(k\)-order derivative in Sobolev space \(W_p^k\) can be performed by spreading the \(k\)-multiple differentiation operator from the space \(C^k.\) At the same time there is a definition of \((k,p)\)-differentiability of a function at an individual point based on the corresponding order of infinitesimal difference between the function and the approximating algebraic polynomial \(k\)-th degree in the neighborhood of this point on the norm of the space \(L_p\). …”
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