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  11. 5991

    Protocol to analyze deep-learning-predicted functional scores for noncoding de novo variants and their correlation with complex brain traits by Enrique Mondragon-Estrada, Sarah U. Morton

    Published 2025-06-01
    “…We describe steps for score prediction, statistical comparison, phenotype correlation, and functional enrichment analysis. This protocol can be generalized to different models and phenotypes.For complete details on the use and execution of this protocol, please refer to Mondragon-Estrada et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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  12. 5992

    Protocol for CRISPR-mediated deletion of cis-regulatory element in murine Th17 cells for in vivo assessment of effector function by Xiancai Zhong, Hongmin Wu, Guanpeng Wang, Zuoming Sun

    Published 2025-06-01
    “…We then detail procedures for in vivo functionality analysis.For complete details on the use and execution of this protocol, please refer to Zhong et al.1,2 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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  13. 5993
  14. 5994

    Remnant cholesterol inflammatory index, calculated from residual cholesterol to C-reactive protein ratio, and stroke outcomes: a retrospective study using the National institutes o... by Yanmei Yu, Yiming Zhang, Chunyan Zhu, Tingting Duan, Zichen Rao

    Published 2025-07-01
    “…This research sought to examine the predictive value of RCII and RC in estimating extent of neurological impairment, assessed using the National Institutes of Health Stroke Scale (NIHSS), and functional recovery, evaluated using the three-month modified Rankin Scale (mRS), among individuals diagnosed with AIS. …”
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  15. 5995

    Research on Function-Interface Design of Old and Antique Hongmu Furniture E-commerce Platform in the Second-hand Economy Environment by Yuhan Li, Yu Feng, Lei Fu, Jiufang Lv

    Published 2025-08-01
    “…These findings suggest that the functional framework should include 24 features, such as expert authentication and institutional certification; in terms of interface design, multiple layout options should be provided for users to choose from, while balancing color schemes and text-to-image ratios. …”
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  16. 5996

    Textele funcționale în manualele de RLS: studiu comparativ / Functional texts in RFL textbooks: a comparative study by Valerica Sporiș

    Published 2025-05-01
    “…We aim to demonstrate the importance of systematically teaching functional texts to foreign students learning Romanian in Romania, in an institutional framework, based on a case study regarding their importance and relevance in RFL textbooks (from A1 to B2), typology and specific exercises. …”
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  17. 5997
  18. 5998

    Optimized fosfomycin regimens for treating carbapenem‐resistant Acinetobacter baumannii in critically ill patients with varying degrees of renal function by Nattapong Tidwong, Anan Chanruang, Suthanya Chupradit, Suzanne L. Parker, Pannee Leelawattanachai, Poramed Winichakoon, Baralee Punyawudho

    Published 2024-10-01
    “…This study aims to evaluate the attainment of PK/PD targets for different dosage regimens of CRAB treatment in critically ill patients based on their renal function. Monte Carlo simulations were conducted to assess the probability of achieving time above the minimum inhibitory concentration (T > MIC) of 80% and 100% and to determine the cumulative fraction response (CFR) against institutional MICs. …”
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  19. 5999

    Rural Water Point Functionality Estimates and Associations: Evidence From Nine Countries in Sub‐Saharan Africa and South Asia by Anna L. Murray, Gabriela Stone, Audrey R. Yang, Nicholas F. Lawrence, Hannah Matthews, Georgia L. Kayser

    Published 2024-02-01
    “…Water points in communities with fewer available water points, those with operational water management committees (which meet often, collect fees, and can name someone for maintenance), and those with financial savings were associated with higher functionality. As piped water system provision increases in line with international development goals, our results suggest that the benefits of providing higher levels of water service should be carefully considered alongside the technological, institutional, and financial investment required to operate and maintain more complex piped water systems in rural settings.…”
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  20. 6000

    Effects of Particulate Matter Exhaust on Functional Parameters of Organ Systems and Reactive Oxygen Species: A Cross-Sectional Study by Manjula Shivanagappa, SS Malini, Thanmayi Mahadeshwara Prasad, D. R. Mahadeshwara Prasad

    Published 2024-12-01
    “…We aimed to study the variation in inflammatory cellular components and oxidative stress markers among exposures along with the variation in functional parameters of the organs involved in detoxifying these nanoparticles, the renal and hepatic system.Methods: After the ethical clearance from Institutional Ethical Committee, IHEC-UOM No. 123PhD/2016-17, a cross-sectional study was undertaken in Molecular Reproductive and Human Genetics Lab, Manasa Gangothri, University of Mysore, Mysore, Karnataka, India during 2015-2019, among 500 male garage workers of age group 18-60years with history of exposure for 6-8 hours a day without using any protective aids during work, for past 6-12 years and 300 controls, who live in areas where they were sparsely exposed. …”
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