DMN network and neurocognitive changes associated with dissociative symptoms in major depressive disorder: a research protocol by Asli Ercan Dogan, Herdem Aslan Genc, Herdem Aslan Genc, Sinem Balaç, Sinem Balaç, Sevin Hun Senol, Görkem Ayas, Zafer Dogan, Emre Bora, Emre Bora, Deniz Ceylan, Deniz Ceylan, Deniz Ceylan, Deniz Ceylan, Vedat Şar

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Complex Assessment of the Functional State of the Urinary System in Preclinical Studies. Part 2. Markers of Nephrotoxicity (Review) by M. V. Miroshnikov, K. T. Sultanova, M. N. Makarova, N. M. Faustova, S. O. Khan, E. A. Loseva

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Birth order or screen time: what strongly predicts executive function skills development in preschool children? by Elena Chichinina, Olga Almazova, Nikolay Veraksa, Nikolay Veraksa

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Usefulness of endoscopic ultrasonography for differentiating between non-functional pancreatic neuroendocrine neoplasm and intrapancreatic accessory spleen by Yuichi Kano, Takuya Ishikawa, Kentaro Yamao, Yasuyuki Mizutani, Tadashi Iida, Kota Uetsuki, Takeshi Yamamura, Kazuhiro Furukawa, Masanao Nakamura, Hiroki Kawashima

“…This retrospective pilot study enrolled 136 patients with pathologically confirmed non-functional PanNEN or IPAS who underwent EUS at our institution. …”
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Visual Functions in Children in Remote Postoperative Period after Laser Treatment of Threshold Stages of Retinopathy of Prematurity by M. V. Pshenichnov, O. V. Kolenko, V. V. Egorov, E. L. Sorokin

“…Purpose. Analysis of visual functions in children in remote postoperative period after laser coagulation (LC) of threshold stages of retinopathy of prematurity (ROP).Patients and methods. …”
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Associations of functional and biochemical parameters of endothelial dysfunction in postmenopausal women with a different state of carbohydrate metabolism by Lyudmila Aleksandrovna Ruyatkina, Irina Sergeevna Iskhakova, Konstantin Yuryevich Nikolaev, Dmitriy Sergeevich Ruyatkin

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Practical application of the International classification of functioning during medical and social expertise of a child with cerebral palsy by O. V. Nazar, O. V. Hdyria, R. O. Moiseienko, V. Yu. Martyniuk, O. A. Vladymyrov

“…A clinical example of measuring the degree of disability of the cerebral palsy child in accordance with the ICF principles using standardized tools for functional status assessment and the ICF Categorical Profile. …”
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Microbial diversity and functional potential of the Halobates melleus (Heteroptera: Gerridae) microbiome from the Red Sea coastline by Juan David Escobar-Prieto, Marc W. Van Goethem, Bob Vernooij, Chakkiath Paul Antony, Lanna Cheng, Himanshu Mishra, Ramona Marasco, Daniele Daffonchio

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Analysing the Functional and Structural Impact of Single Nucleotide Polymorphisms in Matrix Metalloproteinase 3 Gene: An In-silico Approach by Rejitha Ramachandran, Saritha C joseph, kc Sajeevan, Shajee S Nair

“…Introduction: Matrix Metalloproteinase 3 (MMP3) is a vital member of the MMP family, known for its wide range of substrate specificity and proteolytic activity against Extracellular Matrix (ECM) components. The role of functional polymorphisms in the MMP genes has been previously investigated in relation to cancer susceptibility, particularly breast cancer. …”
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Classification of Cell Therapy Products by Cell Manipulation Degree and Functions Performed: Analysis of International Regulatory Approaches by M. A. Vodyakova, N. S. Pokrovsky, I. S. Semenova, V. A. Merkulov, E. V. Melnikova

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Analysis of Data on Adverse Drug Reactions and Functional Flaws of the Pharmacovigilance System Associated with Self-Treatment with Antibiotics by N. V. Verlan, T. L. Moroz, E. O. Kochkina, E. N. Bochanova, E. A. Beigel

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Posterolateral Tibial Plateau Fractures in Adult Anterior Cruciate Ligament Avulsion Effect on Postoperative Knee Function by Bin Feng, Jian Peng, Weizhi Ren, Zhenghui Hu, Jiawei Ouyang, Wei Xu

“…The objective of this study is to investigate the prevalence of PLTPFs in adult ACLAF patients and assess the impact of concurrent PLTPFs on postoperative knee function. Methods This retrospective study analyzed adults, who underwent arthroscopic surgery for ACLAF at our institution between January 2016 and January 2022. …”
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Roxadustat promotes allograft recovery after kidney transplantation: A prospective, multicenter, randomized controlled trial by Mao-Lin Ma, Fei Han, Lei Zhang, Zheng-Yu Huang, Tao Zhang, Heng Li, Jia-Li Fang, Zheng Chen, Ning Na

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Detection of the Risk Factors for Postoperative Asthenopia in Patients with Refractive Disorders by I. A. Mushkova, N. V. Maychuk, A. N. Karimova, L. T. Shamsetdinova

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Corneal Stromal Opacities Accompanied by Hyperopia and Irregular Astigmatism: Two-Step Technology of the Clinical Rehabilitation by I. A. Mushkova, N. V. Maychuk, R. A. Makarov, G. M. Chernakova

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A FORECASTING MODEL ON THE BASIS OF A FUZZY LEARNING SET by Yu. O. German, O. V. German

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Optimizing Treatment Selection for Early Hepatocellular Carcinoma Based on Tumor Biology, Liver Function, and Patient Status by Li X, Xu Y, Ou Y, Li H, Xu W

“…By combining macro-level functional assessments with micro-level biological indicators, this review advocates for a personalized, evidence-based framework to optimize long-term outcomes in early HCC. …”
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4-Octyl Itaconate Modulates Dendritic Cells Function and Tumor Immunity via NRF2 Activation by Zhu B, Zhu L, Ge Z, Zheng S, Dai X, Feng D, Tan L, Sha P, Yao Y

“…The protein level of NRF2 in BMDCs was analyzed by Western blot.Results: Treatment with 4OI represses DC maturation and function. Specifically, 4OI-treated DCs exhibited impaired phenotypic and functional maturation, characterized by decreased expression of co-stimulatory molecules CD40, CD80, and CD86, as well as lower levels of pro-inflammatory cytokines IL-12, IL-6, TNF-α and IL-1β. …”
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Exploring the Pleiotropy of PCSK9: A Wide Range of Influences from Lipid Regulation to Extrahepatic Function by Wang H, Tang G, Wu J, Qin X

“…The purpose of this review is to systematically explore the pleiotropy of PCSK9, extending from its important role in lipid regulation to its extensive effects in extrahepatic tissues, and to reveal its potential role in cardiovascular health, nervous system function, and tumor biology. By integrating the latest research findings, this paper summarizes the complex mechanisms of action of PCSK9 in different biological processes and explores its potential and challenges as a therapeutic target.Keywords: PCSK9, pleiotropy, blood lipid regulation, extrahepatic function…”
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Protocol to derive postganglionic parasympathetic neurons using human pluripotent stem cells for electrophysiological and functional assessment by Christina James, Hsueh-Fu Wu, Jennifer Art, Archie Patel, Nadja Zeltner

“…We then detail procedures for functional assays via multielectrode array (MEA) analysis.For complete details on the use and execution of this protocol, please refer to Wu et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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