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1801
Identification and functional characterization of prognosis-related ferroptosis-associated lncRNAs in colorectal cancer
Published 2025-04-01“…Through multivariate Cox regression analysis, we constructed a prognostic model and selected three key lncRNAs: Lnc-SH2D3A-2, Lnc-LSS-1, and Lnc-PEX11G-4. …”
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1802
Co-dependence of HTLV-1 p12 and p8 functions in virus persistence.
Published 2014-11-01“…These results indicate that efficient viral persistence and spread require the combined functions of p12 and p8.…”
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1803
Functional Characterization of the SHIP1-Domains Regarding Their Contribution to Inositol 5-Phosphatase Activity
Published 2025-01-01“…SHIP1 is commonly known for its involvement in the regulation of the PI3K/AKT signaling pathway by dephosphorylation of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P<sub>3</sub>) at the D5 position of the inositol ring. However, the functional role of each domain of SHIP1 for the regulation of its enzymatic activity is not well understood. …”
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1804
Predicting early functional outcomes in aneurysmal subarachnoid hemorrhage in endovascular coiling and surgical clipping
Published 2025-05-01“…The relative contribution of each significant factor was calculated, and nomograms were constructed accordingly. Model performance was subsequently assessed through validation analyses.ResultsMultivariate analysis identified Hunt–Hess grade, Glasgow Coma Scale (GCS) score, modified Fisher Scale (mFS), D-dimer, age, and body temperature as independent predictors of early functional outcomes following endovascular coiling (all p-values <0.05). …”
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1805
Impact of General Anesthesia and Antioxidants on Cognitive, Static and Locomotor Functions During Laparoscopic Cholecystectomy
Published 2022-04-01“…Neuropsychological testing revealed postoperative cognitive dysfunction on standard therapy which included impaired attention and concentration, executive function, memory, speech, visual constructional skills, abstract thinking, counting, and orientation (21 points on the MoCA scale versus 28–30 points for normal). …”
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1806
Genome-Wide Identification of the TIFY Family in Longan and Their Potential Functional Analysis in Anthocyanin Synthesis
Published 2025-04-01“…A phylogenetic tree was constructed based on the TIFY protein sequences from <i>Arabidopsis</i>, rice, orange, and grape. …”
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1807
Abnormal lipid metabolism and atherosclerosis: a new perspective on organelle function regulation and ferroptosis
Published 2025-08-01“…A nomogram for predicting AS risk was constructed incorporating the expression levels of these five validated Hub genes. …”
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1808
Study on the mechanisms and functions of lncRNAs in regulating carboplatin resistance in ovarian cancer cells
Published 2025-02-01“…Functional annotation and pathway enrichment of differentially expressed lncRNAs were performed using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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1809
Expression characteristics and functional identification of PpD2 gene in peach (Prunus persica)
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1810
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1811
How Do Firms Manage Their Long-term Customer Relationship? The Role of Customer Experience and Constructive Mechanism on Customer Commitment from Utilitarian and Hedonic Perspectiv...
Published 2025-03-01“…This study contributes to the customer relationship management research wherein we can better understand the roles played by customer experience in this constructive mechanism, and comprehend the function of utilitarian and hedonic values. …”
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1812
Integrative Analysis of scRNA-Seq and Bulk RNA-Seq Identifies Plasma Cell Related Genes and Constructs a Prognostic Model for Hepatocellular Carcinoma
Published 2025-02-01“…Functional enrichment, miRNA network construction, and transcriptional regulation analyses were performed to explore underlying mechanisms. …”
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1813
Bioengineering a Human Dermal Equivalent Using Induced Pluripotent Stem Cell-Derived Fibroblasts to Support the Formation of a Full-Thickness Skin Construct
Published 2025-07-01“…These cells form a consistent tissue construct with a structure and composition similar to primary fibroblast controls, which are able to support an overlying epidermis. …”
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1814
Evaluating the construct validity and test-retest reliability of the Orthotic Patient-Reported Outcomes-Mobility (OPRO-M) short forms in lower limb orthosis users.
Published 2025-01-01“…Participants were administered four self-report instruments (OPRO-M, Orthotic and Prosthetic Users Survey - Lower Extremity Functional Status, Lower Extremity Functional Scale, and Patient-Reported Outcomes Measurement Information System - Physical Function) and three performance-based instruments (10-meter Walk Test, Timed Up and Go Test, and Two-Minute Walk Test) during an in-person assessment. …”
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1815
Optimal Allocation of Gas Supply Reliability in Natural Gas Pipeline System Based on Exterior Penalty Function Method
Published 2025-04-01“…Optimal allocation of gas supply reliability is an important part of gas supply reliability of natural gas pipeline system.In order to study the optimal allocation scheme of gas supply reliability with the lowest cost,a cost function model based on the gas supply capacity of the pipeline system was constructed.To address the limitation of traditional intelligent optimization algorithms (e.g.…”
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1816
3D bioprinted dynamic bioactive living construct enhances mechanotransduction-assisted rapid neural network self-organization for spinal cord injury repair
Published 2025-04-01“…This work underscores the critical role of precisely designing cell-instructive bioinks for the advanced functionality of 3D bioprinted living constructs in neural regeneration.…”
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1817
A PEEK Rod-Based Dynamic Instrumentation Construct for the Degenerative Lumbar Spine Disease, First Appraisal Based on Five-year Clinical and Radiological Findings
Published 2025-03-01“…Emphasis was placed on the ability of the construct to prevent adjacent segment disease at an average of 5 years follow-up by maintaining a certain degree of movement in the index segment. …”
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1818
A Construction Method for a Coal Mining Equipment Maintenance Large Language Model Based on Multi-Dimensional Prompt Learning and Improved LoRA
Published 2025-05-01“…This method leverages multi-dimensional prompt learning to guide LLMs in generating high-quality multi-task datasets for coal mining equipment maintenance, ensuring dataset quality while improving construction efficiency. Additionally, a fine-tuning approach based on the joint optimization of a mixture of experts (MoE) and low-rank adaptation (LoRA) is introduced, which employs multiple expert networks and task-driven gating functions to achieve the precise modeling of different maintenance tasks. …”
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1819
In Situ Growth of Au NPs on Nitrogen-Doped Graphene Quantum Dots Decorated Graphene Composites for the Construction of an Electrochemical Immunosensor and Its Application in CEA De...
Published 2025-03-01“…N-GQDs@rGO can be formed through the π–π stacking interaction and possesses a high specific surface area and many functional groups, providing lots of anchor sites (amino moieties in NGQDs) for the in situ electrochemical growth of AuNPs without the addition of reductants and protective agents. …”
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1820
La construction de l’oubli dans le récit mémoriel : le cas du verbe se rappeler à la forme négative
Published 2025-06-01“…Plus spécifiquement, elle analysera les constructions discursives et argumentatives du verbe du souvenir se rappeler à la forme négative dans le récit mémoriel. …”
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