Illumination-adaptative granularity progressive multimodal image fusion method by Chuanyun WANG, Dongdong SUN, Mingqi ZHOU, Tian WANG, Qian GAO, Zhaokui LI

“…Homogeneous and heterogeneous loss functions are constructed based on different environmental conditions, enabling adaptive learning. …”
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FNDC5 and ACOX1 as Biomarkers of Peroxisomal Activity with Contrast Outcomes in Colon Adenocarcinoma by Yuan Hepei, Zeng Jun, Khan Muhammad, Wang Baiyao, Hu Xiaoshan, Wei Hao, Wang Zhaotong, Yuan Yawei

“…FNDC5 was markedly upregulated in cancer cells, and western blot confirmed its elevated protein levels (p < 0.001). Functional assays following FNDC5 knockdown in SW480 and HCT116 cells demonstrated efficient silencing by qPCR and western blot, significantly reduced cell viability (CCK-8 assay), and impaired colony formation, supporting its role as a potential oncogene in colorectal cancer. …”
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DYNAMICS OF CYTOKINES IN ORAL FLUID OF COMPLETELY EDENTULOUS PATIENTS AFTER PROSTHETIC REHABILITATION WITH IMPLANTS by V.A. Ponomarenko, Y.I. Sylenko, M.V. Khrebor

“…After a complete loss of teeth, dentition undergoes involute processes, resulting in significant functional and morphological changes. In practice of rehabilitation of toothless jaws certain difficulty of fixation of dentures on the lower jaw appears. …”
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Bibliometric analysis of laryngeal cancer treatment literature (2003–2023) by Yan Zhao, Jiancheng Xue

“…On the other hand, VOSviewer is designed to construct various types of bibliometric networks and is characterized by its intuitive and user-friendly interface. …”
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Multiple Hub Genes as Diagnostic and Therapeutic Targets Inducing Inflammation and Angiogenesis in Retinopathy of Prematurity by Du C, Tian Y, Liu Y, Shi Y, Chen X, Chai H, Zhang Y, Shen H, Zhang L

“…WGCNA was utilized to obtain oxygen-induced retinopathy (OIR)-related modules, and then key genes were obtained in the intersection of DEGs and the above modules. Biological functions and pathways of key genes were enriched through DAVID, Metascape and Gene set enrichment analysis. …”
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Barriers to and facilitators of clinician acceptance and use of artificial intelligence in healthcare settings: a scoping review by Alex Federman, Yufei Wang, Jalayne J Arias, Catherine E A Scipion, Margaret A Manchester

“…Overall, drivers of clinician AI acceptance and use were ambivalent, functioning as either barriers or facilitators depending on context. …”
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A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand-binding assay by Leire Borrega-Roman, Leire Borrega-Roman, Leire Borrega-Roman, Leire Borrega-Roman, Bradley L. Hoare, Bradley L. Hoare, Miroslav Kosar, Roman C. Sarott, Kacper J. Patej, Jara Bouma, Morgan Scott-Dennis, Morgan Scott-Dennis, Eline J. Koers, Eline J. Koers, Thais Gazzi, Leonard Mach, Sergio Barrondo, Sergio Barrondo, Sergio Barrondo, Joan Sallés, Joan Sallés, Joan Sallés, Wolfgang Guba, Eric Kusznir, Marc Nazaré, Arne C. Rufer, Uwe Grether, Laura H. Heitman, Erick M. Carreira, David A. Sykes, David A. Sykes, Dmitry B. Veprintsev, Dmitry B. Veprintsev

“…The full-length CB2R construct was functional without modification due to its shorter N-terminus. …”
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Regulatory roles of an sRNA derived from the 5´ UTR and sequence internal to lapA in Pseudomonas aeruginosa PAO1 by Xiaojuan Tan, Jingjing Xiao, Qianqian Liu, Ting Yang, Dandan Feng, Ruyi Zheng, Liping Luo, Xi Cheng, Dongsheng Du, Minghui Li, Jinwei Zhou, Guoping Zhu

“…However, some of these novel sRNAs have been functionally characterized. In this study, a previously uncharacterized sRNA, LapS, in P. aeruginosa PAO1 was identified as a novel sRNA. …”
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Immunotherapy combining tumor and endothelium cell lysis with immune enforcement by recombinant MIP-3α Newcastle disease virus in a vessel-targeting liposome enhances antitumor imm... by Lei Li, Feng-Ying Huang, Jin-Yan Wang, Shu-Zhen Dai, Ying-Ying Lin, Guang-Hong Tan, Hengyu Chen, Cai-Chun Wang, Wu-Ping Zheng

“…Moreover, iNDV3α-LP treatment could significantly suppress tumor angiogenesis and reverse the tumor immune suppressive microenvironment in both B16-bearing and 4T1-bearing mice.Conclusions In this study, iNDV3α-LP had several functions, such as tumor and vessel lysis, MIP-3α immunotherapy, and binding to αvβ3-expressing tumor and its neovasculature. iNDV3α-LP treatment significantly suppressed tumor angiogenesis and reversed the tumor immunosuppressive microenvironment. …”
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Immune mechanism of n-butanol extract of Clerodendrum bungei against loach infected with Aeromonas hydrophila by Ya-Jie Li, Xin-Ya Dong, Hong-Hui Li, Hong-Hui Li, Jin-Guo Luo, Xing-Yu Chen, Xu-Dong Zhou

“…The Unique Reads were aligned with the non-coding RNA sequences in the Rfam 13 database using Blast to screen out the non-coding RNAs and identify their types and numbers for further analysis of their functions and regulatory mechanisms. The Reads Count value of miRNA was calculated, and the expression data of the conserved miRNA in each sample were sorted out. …”
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Integration of proteomics and metabolomics analysis investigate mechanism of As-induced immune injury in rat spleen by Xiaoqian Ran, Xi Yan, Guanwei Ma, Zhiyuan Liang, Hongbin Zhuang, Xiaoxiao Tang, Xiaolu Chen, Xueshan Cao, Xukun Liu, Yuhan Huang, Yi Wang, Xinglai Zhang, Peng Luo, Liming Shen

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Identification and Interpretation of Cultural Landscape Field from the Integral Conservation Perspective by Zhitong LIANG, Yan DU, Haiyan XIA

“…Aiming to explore a viable path for the collation and integration of HCHR, this research proposes an innovative framework that shifts from single-entity feature extraction to systemic integrity characterization, investigating how constituent elements functionally interact within integral configurations.MethodsThrough inductive − deductive analysis of literature and case studies, the research first deconstructs the operational logic of cultural landscape approach. …”
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A Study on the Consistency and Efficiency of Student Performance Evaluation Methods: A Mathematical Framework and Comparative Simulation Results by Cecilia Leal-Ramírez, Héctor Alonso Echavarría-Heras, Enrique Villa-Diharce, Horacio Haro-Avalos

“…Methods: We propose a scheme aimed at identifying inconsistencies in student evaluation related to the mathematical framework of the used grading method. To explain the functioning of our construct, we provide mathematical representation of conventional grading methods, including summative assessments, rubrics, and the Systematic Task-Based Assessment Method (STBAM) that we have recently developed, which incorporates both traditional and fuzzy logic-based grading modules. …”
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The PKS–NRPS Gene <i>BBA_09856</i> Deletion Mutant of <i>Beauveria bassiana</i> Enhanced Its Virulence Against <i>Ostrinia furnacalis</i> Larvae and Strengthened the Host Plant’s R... by Yanan Wang, Xiaowei Zou, Xiaomin Zhu, Ji Qi, Jianfeng Liu, Zhengkun Zhang

“…However, they are among the few biosynthetic gene clusters with unknown functions in <i>B. bassiana</i>. To investigate the role of the hybrid PKS–NRPS synthetase gene <i>BBA_09856</i> in <i>B. bassiana</i>, we constructed a mutant strain, ∆<i>BBA09856</i>-WT, by deleting the <i>BBA_09856</i> gene through Agrobacterium-mediated transformation. …”
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Machine learning-derived diagnostic model of epithelial ovarian cancer based on gut microbiome signatures by Cheng Chen, Chengyuan Deng, Yanwen Li, Shuguang He, Yunhong Liu, Shuwen Pan, Wenqian Xu, Lu Fang, Yixi Zhu, Yingying Wang, Xiaoxin Jiang

“…The clinical data and pathological characteristics were comprehensively recorded for further analysis, PICRUSt2 was utilized to conduct an analysis of microbial functional predictions, WGCNA networks were constructed by integrating microbiome and clinical data. …”
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Bioinformatics identification and validation of m6A/m1A/m5C/m7G/ac4 C-modified genes in oral squamous cell carcinoma by Cheng-Hui Lu, Xue-Lai Yin, Zhuo-Deng Huang, Si-Ang Lv, Jun Wu, Jie Wei

“…The four most significantly differentially expressed genes were selected for further functional analysis, and small interfering RNA (siRNA) vectors targeting these genes were transfected into OSCC CAL27 cells. …”
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Patient centered outcomes in stroke: utility-weighted modified Rankin Scale results in a community-based study by Carlos Delfino, Gabriel Cavada, Lorena Hoffmeister, Pablo Lavados, Pablo Lavados, Paula Muñoz Venturelli, Paula Muñoz Venturelli, Paula Muñoz Venturelli

“…We aimed to derive utility-weighted modified Rankin Scale (UW-mRS) values by mapping mRS functional status to EQ-5D-3L scores in a population-based cohort of stroke patients.MethodsThe UW-mRS was obtained by analyzing the EQ5-D-3 L and mRS scores at 180 days after any stroke in the ÑANDU study, a large prospective community-based study in Chile. …”
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The study of promising secure information systems based on signal modeling by V. A. Sizov, D. M. Malinichev, Kh. K. Kuchmezov

“…High data transfer rates in OFDM systems are achieved using parallel information transfer over a large number of orthogonal frequency subchannels (subcarriers) [6].The method of synthesizing signal-code constructions with orthogonal frequency multiplexing provides for different scenarios for the use of semi-square modulation depending on the requirements for interception protection, as well as balancing between spectral and energy efficiency. …”
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Identification of plum PsNAC gene family and its expression patterns in development of fruit hollowness and browning by DENG Honghong, PENG Chao, LIANG Xi, ZHANG Ziyang, LIU Junwei, LI Binqi, WEI Mingkang, WANG Xueying, LI Liumin, CHEN Faxing

“…The MEGA 11 software was used to construct a phylogenetic tree. The online tool Simple MEME Wrapper was used to analyze the motifs. …”
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Introduction by Verena Balz

“…They all sought for comprehensiveness through considering a multitude of aspects that influence the form and functioning of this development. In all practices, the production of spatial representations, maps and models, was a core activity. …”
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