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14001
Support of individual educational trajectories based on the concept of explainable artificial intelligence
Published 2022-01-01“…The algorithm for constructing recommendations is divided into stages and provides for variability in decision making.Scientific novelty. …”
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14002
Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway
Published 2025-04-01“…Furthermore, subcutaneous tumor xenograft models in nude mice were constructed to assess the effects of PRDX2 knockdown and the PRDX2 inhibitor Conoidin A on tumor growth in vivo. …”
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14003
Identification of Genes for Improving Cold Sensitivity in Nerve-Damaged Rats Via Lumbar Sympathectomy Using Poly(A)-seq
Published 2025-06-01“…We identified 174 DEGs in the gene expression profile of lumbar sympathectomized SNI rats, including 69 upregulated and 105 downregulated genes, compared with SNI model rats. Functional analysis of the DEGs revealed that the most significantly enriched pathways included immune-related pathways and cellular molecular components, which mediate neuroinflammation, central sensitization, and chronic pain. …”
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14004
Effect of Human Resource Interventions on Innovation Performance The Mediating Role of Innovative Work Behavior
Published 2025-06-01“…The primary goal was to analyse the influence of interventions in human resources on performance in innovation, with innovative work behaviours functioning as a mediator in corporations in Jordan. …”
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14005
Machine learning identification of key genes in cardioembolic stroke and atherosclerosis: their association with pan-cancer and immune cells
Published 2025-07-01“…The area under the curve was > 0.7 for both models constructed using CS and AS datasets. A strong correlation was observed between neutrophil levels and expression of the hub genes. …”
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14006
Network Pharmacology and Metabolomics Reveal Anti-Ferroptotic Effects of Curcumin in Acute Kidney Injury
Published 2024-12-01“…Molecular docking and enzyme activity assay was carried out to evaluate the effects of Cur on MAOA.Results: Our results showed that in vivo Cur preserved renal functions in AKI mice by lowering levels of serum creatinine, blood urea nitrogen, while in vitro ameliorated the cell viability of HK-2 cells damaged by ferroptosis. …”
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14007
Activation of angiopoietin-1 signaling with engineering mesenchymal stem cells promoted efficient angiogenesis in diabetic wound healing
Published 2025-02-01“…MSCANG1 notably enhanced the survival and tubulogenesis of endothelial cells and promoted the expression of junction proteins, facilitating the establishment of functional vasculature with improved vascular leakage. …”
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14008
Non-invasive urinary proteomic biomarkers for prognostic assessment in sepsis
Published 2025-07-01“…Nomogram model and ROC curves were constructed to evaluate the predictive efficacy of these identified protein biomarkers. …”
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14009
ZF-HD gene family in rapeseed (Brassica napus L.): genome-wide identification, phylogeny, evolutionary expansion and expression analyses
Published 2024-12-01“…Conclusions These findings provide a basis for a comprehensive understanding of the ZF-HD family in rapeseed, which will provide information for further research on the functional characteristics of the BnZHD genes.…”
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14010
Anticoronavirus activity of C60 fullerene: in silico and in vitro screening
Published 2025-08-01“…The CHARMM-GUI and SwissParam web resources were used to construct the membrane and C60 fullerene, respectively. …”
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14011
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14012
ANÁLISE DAS VARIÁVEIS DE UMA AMOSTRA DE CERÂMICA PAPEBA
Published 2012-01-01“…Furthermore, the fundamental characteristic within these differences did not indicate distinct cultural traditions, but instead the functional utilization of three classes of pots. Therefore, the data do not indicate the presence of two ethnic components at the site. …”
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14013
AI in Medical Questionnaires: Innovations, Diagnosis, and Implications
Published 2025-06-01“… This systematic review aimed to explore the current applications, potential benefits, and issues of artificial intelligence (AI) in medical questionnaires, focusing on its role in 3 main functions: assessment, development, and prediction. …”
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14014
Combination of RNA-sequencing data analysis, network pharmacology, molecular docking techniques to investigate the mechanism of Prunella vulgaris L. in the treatment of non-small c...
Published 2025-05-01“…Protein–protein interaction (PPI) network was constructed using a STRING database and core targets were obtained via Cytoscape 3.9.0 software. …”
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14015
Spatial transcriptomic characteristics of gastric cancer in young and the expression and role of TMEM176B in gastric cancer cells
Published 2025-05-01“…Methods The surgical specimens of six patients with GCY were included to construct a tissue microarray containing the tumor core region (TCR), cancer-adjacent tissue (CAT), and normal gastric tissue (NGT). …”
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14016
Formation of a Generalized System of Indicators of Regional Economic Security
Published 2024-11-01“…The topic of the study is relevant, since the prevention of crisis situations, the organization of stable functioning of regional economies, the development of territories and the growth of the standard of living of the population necessitate constant monitoring of the economic security of the regions of Russia, which is based on the modeling of a system of indicators, because socioeconomic development is a complex system of interconnections, various components of the economy.Data and methods. …”
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14017
Study on the molecular mechanism of UBA52 and BARD1 regulating hepatocellular carcinoma through the PI3 K/AKT signaling pathway
Published 2025-05-01“…Methods This study integrated HCC datasets (GSE135631, GSE184733, GSE202853) from the gene expression omnibus (GEO) database to screen for differentially expressed genes (DEGs), perform functional enrichment analysis, weighted gene co-expression network analysis (WGCNA), construct protein–protein interaction (PPI) networks, and conduct survival analysis. …”
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14018
The anti-aging potential of antihypertensive peptides of Pariset, a dataset of algal peptides
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14019
“It’s like going through life at a mediocre level”: a qualitative study of the meaning and impact of fatigue in children and young people with sickle cell disease
Published 2025-05-01“…Conclusions Fatigue dominates CYP’s experience of living with SCD, significantly impacting their physical, social and educational functioning and leading to isolation and stigma. Often overlooked in clinical settings, addressing fatigue should be integral to SCD care and research. …”
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14020
Research on the Coordinated Development of “Node-Place” in Intercity Railway Station Areas: A Case Study of the Guangdong–Hong Kong–Macao Greater Bay Area, China
Published 2025-03-01“…Their stations are usually distributed based on densely populated and economically active areas, and they also play roles as regional network nodes, intra-city nodes, and functional areas. However, the academic research on the spatial development of station areas is still very limited. …”
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