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13801
Genome‐Wide Association Analyses Identify Hydrogen Peroxide–Responsive Loci in Wheat Diversity
Published 2025-04-01“…The result will also help to construct genetic map for H2O2‐mediated root–shoot growth variation.…”
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13802
Spatial–Temporal Heterogeneity of Wetlands in the Alpine Mountains of the Shule River Basin on the Northeastern Edge of the Qinghai–Tibet Plateau
Published 2025-03-01“…Alpine wetland ecosystems, as important carbon sinks and water conservation areas, possess unique ecological functions. Driven by climate change and human activities, the spatial distribution changes in alpine wetlands directly affect the ecosystems and water resource management within a basin. …”
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13803
Hyperbranched Thermosensitive Polymer-AuNP Composite Probe for Temperature Colorimetric Detection
Published 2024-11-01“…And it was combined with gold nanoparticles (AuNPs) prepared by a sodium citrate reduction method to construct an HPEI-IBAm-AuNP colorimetric probe. The probe exhibits excellent stability, even at salt concentrations of up to 12 g/L, thanks to the abundant amino functional groups and the large steric hindrance effect unique to HPEI-IBAm. …”
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13804
Exploration of drug repurposing for Mpox outbreaks targeting gene signatures and host-pathogen interactions
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13805
Pharmacological mechanisms of berberine against triple negative breast cancer: Integration of network pharmacology and experimental validation
Published 2025-08-01“…In the analysis of gene ontology (GO) enrichment results of effective target GO functional enrichment analysis suggested that BBR may be involved in protein phosphorylation and anti-apoptotic biological processes. …”
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13806
Cation-induced topical disordered niobium nickel oxide for robust hydrogen storage in magnesium hydride
Published 2025-07-01“…Herein, efficient regulation of electronic and structural rearrangements in niobium-rich nickel oxides was achieved through precise compositional design and niobium cation functionalized doping, thereby greatly enhancing its intrinsic catalytic activity in hydrogen storage systems. …”
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13807
Analysis of the clinicopathological characteristics, genetic phenotypes, and prognostic of pure mucinous adenocarcinoma
Published 2020-01-01“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses were performed to explore the functional importance of underlying molecular changes. …”
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13808
Ability of SPP1 to Alleviate Post‐Intracerebral Hemorrhage Ferroptosis via Nrf2/HO1 Pathway
Published 2025-05-01“…A protein–protein interaction network was constructed using Cytoscape, and hub genes were identified. …”
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13809
Predicting clinical outcome in posterior circulation large-vessel occlusion patients with endovascular recanalisation: the GNC score
“…Multivariable logistic regression was employed to construct the scoring system.Results The training cohort comprised 92 patients, of whom 52 (56.5%) experienced poor outcomes. …”
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13810
Barriers and Facilitators to Adherence to Exercise-Based Cardiac Rehabilitation Among Coronary Artery Disease Patients: A Scoping Review
Published 2025-05-01“…These factors were mapped onto the Behaviour Change Wheel, and the APEASE criteria were applied to determine appropriate intervention functions. Finally, Behaviour Change Techniques were matched to these intervention functions.Results: Seventeen studies were included, identifying multiple core domains of the Theoretical Domains Framework influencing EBCR adherence. …”
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13811
Klebsiella pneumoniae under xylose pressure: the growth adaptation, antimicrobial susceptibility, global proteomics analysis and role of XylA and XylB proteins
Published 2025-04-01“…Additionally, while the growth adaptation of K2044−8Xyl−60G under xylose pressure was confirmed, no amino acid mutations were detected in the functional proteins of this xylose-induced isolate, suggesting that persistent xylose pressure does not cause nonsense mutations in the bacterial genome. …”
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13812
Immune analysis according to Lauren type for gastric cancer and its significance in individual treatment and prognostic prediction
Published 2025-07-01“…The diffuse subtype had more immune cells but was less functional than the intestinal subtype. Notably, checkpoints were highly expressed among diffuse-type patients. …”
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13813
A Specific and Sensitive Immuno-Terahertz Method to Detect Pathogenic Microorganisms
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13814
Metabolic pathway activation and immune microenvironment features in non-small cell lung cancer: insights from single-cell transcriptomics
Published 2025-02-01“…Wet lab experiments validated the role of KRT6B in NSCLC, demonstrating that KRT6B expression is elevated and it stimulates the proliferation of cancer cells.DiscussionThese observations not only enhance our understanding of metabolic reprogramming and its biological functions in NSCLC but also provide new perspectives for early detection, prognostic evaluation, and targeted therapy. …”
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13815
SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome
Published 2025-05-01“…Functional studies demonstrated that SNHG12 knockdown impaired glycolysis in KGN cells, while SNHG12 overexpression partially restored glycolysis. …”
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13816
Identification and attribution analysis of integrated ecological zones based on the XGBoost-SHAP model: A case study of Chengdu, China
Published 2025-08-01“…Rapid urbanization has intensified pressure on regional ecosystems, constraining sustainable development. Constructing a scientific ecological zoning framework is essential for environmental protection and refined territorial spatial management. …”
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13817
Long-read transcriptomics of caviid gammaherpesvirus 1: compiling a comprehensive RNA atlas
Published 2025-03-01“…Using nanopore long-read RNA sequencing, we annotated the CaGHV-1 genome and constructed a detailed transcriptomic atlas. Our findings reveal diverse viral mRNAs and non-coding RNAs, along with mapped promoter elements for each viral gene. …”
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13818
Defining criteria for disease activity states in juvenile dermatomyositis based on the Juvenile Dermatomyositis Activity Index
Published 2024-02-01“…Cut-off validation was conducted by assessing construct and discriminative ability in two cohorts including a total of 488 JDM patients.Results The calculated JDMAI1 cut-offs were ≤2.4 for ID, ≤6.6 for LDA, 6.7–11 for MDA and >11 for HDA. …”
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13819
The protective role and mechanism of ginkgolide B in regulating mTOR signalling pathway involved in Manganese-induced apoptosis and autophagy in N27 cells
Published 2025-07-01“…Ginkgolide B (GB) is a diterpenoid compound found in the leaves of the traditional Chinese medicine plant Ginkgo biloba, which has been shown to have a variety of pharmacological functions. However, the role of GB in Manganese(Mn)-induced apoptosis and autophagy in neuronal cells remains poorly understood. …”
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13820
Single-cell sequencing uncovers a high ESM1-expression endothelial cell subpopulation associated with bladder cancer progression and the immunosuppressive microenvironment
Published 2025-03-01“…The heterogeneity and biological functions of tumor endothelial cells (ECs) during BC progression remain poorly understood. …”
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