Dynamical patterns of EEG connectivity unveil Parkinson’s disease progression: insights from machine learning analysis by Caroline L Alves, Loriz Francisco Sallum, Francisco Aparecido Rodrigues, Thaise G L de O Toutain, Patrícia Maria de Carvalho Aguiar, Michael Moeckel

“…EEG was recorded using a 32-channel Biosemi Active-Two system (512 Hz), with signals segmented into non-overlapping 10 s windows. Functional connectivity matrices were constructed using multiple metrics, including coherence, Pearson, Spearman, canonical correlation, and Ledoit–Wolf shrinkage. …”
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Bayesian estimation of pore size distribution in porous carbon using a novel GCMC-based kernel incorporating surface roughness by Shotaro Hiraide, Naruaki Fuse, Kohei Yamamoto, Hideki Tanaka, Kazuyuki Nakai, Satoshi Watanabe

“…GCMC provides a thermodynamically rigorous description of adsorption, surpassing classical density functional theory (DFT). Building on these simulations, we construct a new kernel, termed rGCMC (roughness-integrated GCMC), which embeds energetic and geometric heterogeneities via patchwise offsets in a slit-pore model to effectively capture surface roughness. …”
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Caged-hypocrellin mediated photodynamic therapy induces chromatin remodeling and disrupts mitochondrial energy metabolism in multidrug-resistant Candida auris by Xinyao Liu, Yiran Tao, Linwan Zhang, Yuzhou Liu, Dongmei Shi, Jiao Wang, Peng Xue, Bin Xu, Wenjie Fang, Yuping Ran

“…To investigate COP1T-HA-mediated PDT-induced genomic alterations, we constructed a 3D genome map of Candida species, which uncovered the reorganization of chromatin architecture in response to PDT treatment. …”
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Piezoelectric-triboelectric hybrid nanogenerator based on tough, stretchable BaTiO3 doped antibacterial hydrogel for self-powered sensors by Runi Hou, Lijian Xu, Maolin Yu, Zengmin Tang, Bin Zhou, Qiao Zhang, Na Li, Jianxiong Xu

“…Subsequently, a kind of PTENG was constructed by employing the O/P/Fe-BTO hydrogels as electrode materials. …”
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Some issues of local drinking water supply of the population during martial law (using the example of Ukrainian cities with a population of over 100 thousand people). Part 2 by Yu. F. Rudenko, N. A. Yurkova, O. V. Gural, V. Yu. Saprykin

“…The long period of military action in Ukraine has revealed a number of problems associated with the stable functioning of a modern centralized water supply system in emergency situations. …”
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Study of bioactive 3D-printed scaffolds incorporating zinc-based MOF for bone defect repair and anti-inflammatory applications by Yu Han, Xiufeng Jia, Yinwei Yang, Pei Guo, Chao Li, Yunze Zhang, Li Yin, Bo Jia, Haitao Wang

“…The Zn-MOF component mediated sustained release of Zn2+ ions (cumulative release: 89.6 ± 9.08 % over 18 days). This dual-functional system synergistically combines MCF-driven cellular recruitment with Zn2+-mediated immunomodulation, creating a pro-regenerative microenvironment. …”
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USP14 promotes osteoarthritis progression by deubiquitinating FZD8 to activate the Wnt/β-catenin signaling pathway by Xiaochao Chen, Tiancheng Ma, Yongfeng Chen, Qiang Sun, Huayi Wang, Yuanrui Wang

“…In this study, we aimed to explore the functions of ubiquitin specific peptidase 14 (USP14) in OA development. …”
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Machine learning-assisted multi-dimensional transcriptomic analysis of cytoskeleton-related molecules and their relationship with prognosis in hepatocellular carcinoma by Yuxuan Li, Mingbo Cao, Xiaorui Su, Gaoyuan Yang, Yupeng Ren, Zhiwei He, Zheng Shi, Ziyi Hu, Guirong Liang, Qi Zhang, Zhicheng Yao, Meihai Deng

“…Prognostic models were constructed using LASSO regression and random forest algorithms, and validated in two independent cohorts (ICGC LIRI-JP and CHCC-HBV). …”
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Multiple analytical perspectives of mitochondrial genes in the context of preeclampsia: potential diagnostic markers by Can Li, Can Li, Fang Liu, Chao Li, Xiangzhong Zhao, Qiulan Lv, Aiping Jiang, Shuping Zhao

“…GO and KEGG analysis were performed to elucidate the functions of the MMRDEGs. A diagnostic model using Random Forest and logistic regression was validated by ROC curve analysis. mRNA expressions of OCRL, TPI1, GAPDH, and LDHA were quantified via qPCR. …”
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Initial Screening of Extrachromosomal Circular DNA Candidates for Pork Meat Quality Traits Using Circle-Seq and RNA-Seq Analysis by Liyao Bai, Jiahao Wu, Tengfei Dou, Donghui Chu, Xinjian Li, Xuelei Han, Ruimin Qiao, Kejun Wang, Feng Yang, Xiuling Li

“…The results showed that 1325 and 1304 differentially expressed eccDNAs were identified in the YN and YL groups, varying in size and distributed across multiple genomic functional regions. These eccDNAs were also annotated according to several protein-coding genes. …”
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Development and application of a cGPS 20K liquid-phase SNP microarray in Jiaji ducks by Tieshan Xu, Zixin Xu, Dingping Bai, Fanghu Wu, Yuanyuan Shang, Mao Li, Guang Rong, Lihong Gu

“…In conclusion, this independently designed microarray will be useful for large-scale genotyping and can lay the foundation for future screening of mutation loci and functional genes.…”
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A prognostic model for head and neck squamous cell carcinoma based on radiotherapy sensitivity insights from nasopharyngeal carcinoma by Yinjiao Fei, Zhen Liu, Jinling Yuan, Lei Qiu, Yuchen Zhu, Kexin Shi, Jinyan Luo, Mengxing Wu, Weilin Xu, Shu Zhou

“…This study aimed to identify radiotherapy sensitivity-related genes and construct a prognostic model for HNSCC, incorporating insights from nasopharyngeal carcinoma (NPC) as a related subtype. …”
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Hypoxic preconditioning modulates BDNF signaling to alleviate depression-like behaviors in mice and its whole transcriptome sequencing analysis by Lizhu Chen, Xujie Wang, Xiaoe Jia, Rengui Bade, Xiaolei Liu, Shuyuan Jiang, Yabin Xie, Wei Xie, Manhai Gao, Guo Shao

“…The ceRNA networks were constructed on the basis of these DERNAs. Functional enrichment analysis revealed that these genes are related to synapses, neurogenesis and neurotrophin signaling. …”
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Development of a CRISPR/Cas9 genome editing toolbox for Corynebacterium stationis and its application in hypoxanthine biosynthesis by Zhilin Ouyang, Xinyu Zhang, Xinyi Hou, Jiabei Huang, Ying Lin, Suiping Zheng

“…First, electroporation efficiency was optimized to 1.81 ± 0.16 × 105 CFU (colony forming units)/μg plasmid DNA through medium selection, pulse parameter adjustments (2.5 kV, 2 pulses), and concentration optimization of cell wall-weakening agents (3.0 % glycine, 0.25 % isoniazid). Three functional shuttle vectors (p99E-pCG1, p19-Kan, p19-Spe) were constructed, enabling stable heterologous gene expression. …”
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FimC binds to the promoter region of agn43 to modulate autoaggregation by Zhihao Wang, Xiangpeng Niu, Ningyuan Zhong, Lanfang Kong, Saqib Nawaz, Haiyang Zhang, Wei Jiang, Yuanyuan Liu, Jian Tu, Xiangan Han

“…It also highlights the importance of fimC in the biofilm formation and adhesion ability of APEC, which provides new insights into the functions of the fimbrial chaperone protein FimC.…”
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Revealing heterogeneity in mild cognitive impairment based on individualized structural covariance network by Xiaotong Wei, Ronglong Xiong, Ping Xu, Tingting Zhang, Junjun Zhang, Zhenlan Jin, Ling Li

“…Finally, correlation analysis and functional annotation further revealed that the affected edges were related to cognitive performance and implicated in memory and emotion terms. …”
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Identification of matrix stiffness-related molecular subtypes in HCC via integrating multi-omics analysis and machine learning algorithms by Hanqi Li, Jiayi Zhang, Yu Shi, Huanhuan Wang, Ruida Yang, Shaobo Wu, Yue Li, Xue Yang, Qingguang Liu, Liankang Sun

“…A matrix stiffness-related signature comprising 57 genes was constructed by evaluating 101 machine learning algorithm combinations. …”
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The stress regulator FgWhi2 and phosphatase FgPsr1 play crucial roles in the regulation of secondary metabolite biosynthesis and the response to fungicides in Fusarium graminearum by Jie Zhang, Han Gao, Fuhao Ren, Zehua Zhou, Huan Wu, Huahua Zhao, Lu Zhang, Mingguo Zhou, Yabing Duan

“…In this study, we identified homologous genes of WHI2 and PSR1 in F. graminearum and evaluated their functions by constructing deletion mutants. By comparing the responses of the mutants to different stressors, we found that FgWHI2 and FgPSR1 were involved in responding to osmotic, cell wall and cell membrane stresses, while also affecting the sexual and asexual reproduction in F. graminearum. …”
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From rings to regions: modeling and mapping climate-driven timber production zones for Cyclocarya paliurus by integrating niche models and growth traits by Zijie Zhang, Zijie Zhang, Zhengyang Ye, Xulan Shang, Xulan Shang, Wanxia Yang, Wanxia Yang, Tongli Wang, Shengzuo Fang, Shengzuo Fang

“…IntroductionCyclocarya paliurus, a native hardwood species with multi-functional value, has been prioritized in China’s National Reserve Forest Program. …”
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A new scheme for boosting in situ Fenton-like reaction in plant pathogenic tissues for selective structural degradation of capsid proteins by Jun Ma, Ming Chen, Yujie Wang, Jiaying Li, Jian Tang, Shengjun Wu, Chi He, J. Paul Chen

“…Our research demonstrated that tCuinter-bCDs possessed functional activity to specifically recognize and proximally degrade CP. tCuinter-bCDs form complexes with CP monomers through supramolecular bonds characterized by significant electrostatic components. …”
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