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13701
Gene expression analysis reveals mir-29 as a linker regulatory molecule among rheumatoid arthritis, inflammatory bowel disease, and dementia: Insights from systems biology approach...
Published 2025-01-01“…We identified common differentially expressed genes (DEGs) and constructed a gene-gene interaction network. Subsequently, topology analysis for hub gene identification, cluster and functional enrichment, and regulatory network analysis were performed. …”
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13702
Gene signatures and immune correlations in Parkinson’s disease Braak stages
Published 2025-04-01“…Furthermore, transcription factors (TFs) and miRNAs targeting the hub genes network were constructed. After verifying hub gene expression level through independent data sets. …”
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13703
Key wound healing genes as diagnostic biomarkers and therapeutic targets in uterine corpus endometrial carcinoma: an integrated in silico and in vitro study
Published 2025-01-01“…Genetic alteration analysis indicated frequent mutations in FN1 and KDM6A, although these did not significantly affect survival. Functional analysis using the CancerSEA database highlighted the involvement of these genes in critical cancer-related processes, including angiogenesis, apoptosis, and metastasis. …”
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13704
The Production of the Recombinant Protein of Anthrax Bacteriolysine PlyPH and In Vitro Study of the Lytic Properties of the Protein Coded for them Against Bacillus anhracis Microbi...
Published 2023-07-01“…Based on the obtained amplification products and the pTrcHis2C vector, we constructed a recombinant plasmid containing the bacteriolysin synthesis PlyPH gene and stably functioning in the cells of the recombinant E. coli strain. …”
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13705
Reliability and validity of the Turkish version of lumbar stiffness disability index
Published 2024-09-01“…The validity and reliability of the lumbar stiffness disability index (LSDI) in Türkiye, which measures the impact of lumbar stiffness on functional abilities, have not yet been confirmed. This study aims to test the validity and reliability of the Turkish version of LSDI (Tr-LSDI). …”
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13706
Comprehensive Comparative Rating Assessment of Meat- Processing Enterprises in the Vologda Region
Published 2025-03-01“…A rating of enterprises was constructed based on the indexes of integrated levels of their comparative assessments, which made it possible to formulate the functional characteristics of meat product manufacturers for the population based on the degree of their participation in ensuring the development potential of the regional commodity brand “True Vologda Product”. …”
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13707
A Chemotherapy Response-Related Gene Signature and DNAJC8 as Key Mediators of Hepatocellular Carcinoma Progression and Drug Resistance
Published 2025-03-01“…DNAJC8’s role in hepatocellular carcinoma cell functions and chemotherapy resistance was further explored through gene knockdown experiments in vitro and in vivo.Results: Differential expression analysis identified 220 common genes associated with chemotherapy response. …”
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13708
Statistics as a Reflection of the Influence of Factors on the Economic Behavior of Households
Published 2025-03-01“…The relevance of the study is due to the importance of economic behavior, which is influenced by various factors that activate the functions of the population related to the needs, desires, values and orientations of people. …”
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13709
A Zinc Oxide Interconnected Hydroxypropyl-Beta-Cyclodextrin/rGO Nanocomposite as an Electrocatalyst for Melatonin Detection: An Ultra-Sensitive Electrochemical Sensor
Published 2025-05-01“…Nanocomposite hydroxypropyl-beta-cyclodextrin functionalized reduced graphene oxide sheets (HpβCD@rGOs) with zinc oxide flaky structures (ZnOFs) were synthesized. …”
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13710
Epidemic Models with Varying Infectivity on a Refining Spatial Grid—I—The SI Model
Published 2024-09-01“…The migration processes in either of the two states are assumed to be Markovian. We establish a functional law of large numbers by letting the initial approximate number of individuals on each node, <i>N</i>, to go to infinity and the mesh size of the grid, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>ε</mi></semantics></math></inline-formula>, to go to zero jointly. …”
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13711
Raster Image-Based House-Type Recognition and Three-Dimensional Reconstruction Technology
Published 2025-04-01“…To address the limitations of existing public datasets—including low quality, inaccurate annotations, and poor alignment with residential architecture characteristics—this study constructs a high-quality vector dataset of raster house plans. …”
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13712
Protective effect of Pu-erh tea polysaccharides and catechins compound on immunosuppressive mice
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13713
An immune relevant signature for predicting prognoses and immunotherapeutic responses in patients with muscle‐invasive bladder cancer (MIBC)
Published 2020-04-01“…Genome (gene mutation and copy number variation), transcriptome (mRNA, lncRNA, and miRNA), and functional enrichment were found to be heterogeneous among different immune‐infiltrating groups. …”
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13714
Uncovering active ingredients and mechanisms of Pholiota adiposa in the treatment of Alzheimer’s disease based on network pharmacology and bioinformatics
Published 2025-07-01“…Our study employs network pharmacology and machine learning to uncover its therapeutic potential. We constructed a network of AD-relevant target proteins using databases like TCMSP, CTD, and GeneCards, and performed gene enrichment and functional analysis with DAVID, GO, and KEGG via Hiplot. …”
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13715
Comparison of combined femoral nail and plate fixation versus dual plate fixation in the treatment of AO/OTA 33C distal femoral fractures
Published 2025-08-01“…Both fixation strategies provided stable constructs, facilitated early recovery, and resulted in satisfactory functional outcomes. …”
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13716
Identification and validation of aging related genes in osteoarthritis
Published 2025-05-01“…In addition, a nomogram was constructed based on the key genes to predict OA risk, and its diagnostic value was evaluated using ROC curves. …”
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13717
Formulation, Characterization, and Determination of the Rheological Profile of Loquat Compote Mespilus Germánica L. through Sustenance Artificial Intelligence
Published 2023-01-01“…The theme of the presented study is to create a compote that is functional, inexpensive in cost, free of preservatives, and will have long shelf life, as well as to assess its rheological, sensory, and physicochemical properties. …”
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13718
Measurement properties of the Swedish version of the Knee Self‐Efficacy Scale: A Rasch analysis
Published 2025-04-01“…Clinicians are therefore advised to interpret the subscale scores cautiously, acknowledging the multidimensional nature of the constructs measured. Level of Evidence Level III.…”
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13719
ERBB3-related gene PBX1 is associated with prognosis in patients with HER2-positive breast cancer
Published 2025-01-01“…Three algorithms, LASSO, RandomForest and XGBoost were combined to identify the signature genes. we construct risk models and generate ROC curves for prediction. …”
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13720
A Prospective Study of Lumbar Facet Arthroplasty in the Treatment of Degenerative Spondylolisthesis and Stenosis: Early Cost-effective Assessment from the Total Posterior Spine Sys...
Published 2022-03-01“…# Background Given the increased attention to functional improvement in spine surgery as it relates to motion preservation, activities of daily living, and cost, it is critical to fully understand the healthcare economic impact of new devices being tested in large FDA randomized controlled trials (RCT). …”
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