DSUP modified mesenchymal stem cells exert significant radiation protective effect by enhancing the hematopoietic niche by Fu-Dong Chen, Biao Zhang, Li-Li Wang, Ya-Li Jia, Quan Zeng, Tao Fan, Hai-Yang Wang, Ming-Fang Xiong, Ying-Xue Lin, Jun-Nian Zhou, Wen Yue, Li Chen, Jia-Fei Xi

“…In the HSPCs-MSCs co-culture model, DSUP modified MSCs have significant protective effect on HSPCs by providing a functional hematopoietic niche after radiation damage. …”
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Integrative analysis of T cell-associated markers in Ewing sarcoma reveals prognostic signatures and immune dynamics by Umair Ali Khan Saddozai, Umair Ali Khan Saddozai, Chenxu Liu, Chenxu Liu, Fei Yan, Zhendong Lu, Muhammad Babar Khawar, Muhammad Babar Khawar, Muhammad Usman Akbar, Saadullah Khattak, Haibo Sun, Haibo Sun, Ping Yang

“…A prognostic model based on CLEC11A, BDP1, and ID3 was constructed using Cox regression and validated in external datasets. …”
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Machine learning and multi-omics analysis reveal key regulators of proneural–mesenchymal transition in glioblastoma by Can Xu, Jin Yang, Huan Xiong, Xiaoteng Cui, Yuhao Zhang, Mingjun Gao, Lei He, Qiuyue Fang, Changxi Han, Wei Liu, Yangyang Wang, Jin Zhang, Ying Yuan, Zhaomu Zeng, Ruxiang Xu

“…The Lasso, Cox, and Step machine learning algorithms were used to construct and screen the optimal risk assessment prognostic model. …”
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Machine Learning Reveals Aneuploidy Characteristics in Cancers: The Impact of BEX4 by Aizhong Xu, Jianjun Liu, Li Tong, Tingting Shen, Songlin Xing, Yujie Xia, Bosen Zhang, Zihao Wu, Wenkang Yuan, Anhai Yu, Zijie Kan, Wenqi Yang, Chao Zhang, Chong Zhang

“…Mfuzz expression pattern clustering and functional enrichment were applied to genes with BEX4 as the core to explore their regulatory mechanisms. …”
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Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development by Piotr Jaholkowski, Shahram Bahrami, Vera Fominykh, Guy F.L. Hindley, Markos Tesfaye, Pravesh Parekh, Nadine Parker, Tahir T. Filiz, Kaja Nordengen, Espen Hagen, Elise Koch, Nora R. Bakken, Evgeniia Frei, Viktoria Birkenæs, Zillur Rahman, Oleksandr Frei, Jan Haavik, Srdjan Djurovic, Anders M. Dale, Olav B. Smeland, Kevin S. O’Connell, Alexey A. Shadrin, Ole A. Andreassen

“…To provide biological insights loci were functionally characterized. Subsequently, we constructed a Structural Equation Model (SEM) to determine if the polygenic foundation of cognition has a direct impact on Alzheimer's disease risk, or if its effect is mediated through established risk factors for the disease, using a case-control sample from the UK Biobank. …”
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Oxidative stress-related biomarkers in thyroid eye disease: evidence from bioinformatics analysis and experimental validation by Yuanping Hai, Yuanping Hai, Qintao Ma, Zhitao Liu, Dongxiao Li, Anqi Huang, Yan Zhu, Duan Yongbo, Cheng Song, Genfeng Yu, Sijie Fang, Lan Liu, Yi Wang, Yi Wang, Thomas Efferth, Jie Shen

“…A nomogram model was constructed using logistic regression based on selected oxidative stress-related core genes. …”
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Biotinylated fusion protein-streptavidin-peroxidase complex based non-competitive magnetic immunoassay for rapid detection of organophosphorus pesticides by Ruirui Shi, Jiangke Li, Wenli Yu, Tengfei Yin, Haiyan Lin, Juan Liu, Wenyu Cui

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Enteric Elongation Induced by a Novel Sleeve Device in a Live Roux-en-Y Configuration by Joshua C. Colvin, Collyn C. O’Quin, Hannah R. Meyer, Valerie L. Welch, Giovanni F. Solitro, Jonathan S. Alexander, Donald L. Sorrells

“…Future constructs of the IES may benefit from the addition of immunomodulators. …”
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Identification of hub genes, non-coding RNAs and pathways in Renal cell carcinoma (RCC): A comprehensive in silico study by Ahmad Golestanifar, Hengameh Khedri, Parisa Noorabadi, Mohammadreza Saberiyan

“…Our approach combined differential expression analysis, functional enrichment through Gene Ontology (GO) and KEGG pathway mapping, and a Protein-Protein Interaction (PPI) network to identify crucial hub genes in KIRC progression. …”
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Chemical Space Exploration and Machine Learning-Based Screening of PDE7A Inhibitors by Yuze Li, Zhe Wang, Shengyao Ma, Xiaowen Tang, Hanting Zhang

“…Subsequently, a machine learning model employing the Random Forest–Morgan pattern was constructed for the qualitative and quantitative prediction of PDE7A inhibitors. …”
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A Machine Learning‐Based Observation Operator for FY‐4B GIIRS Brightness Temperatures Considering the Uncertainty of Label Data by Yonghui Li, Wei Han, Wansuo Duan, Zeting Li, Hao Li

“…Moreover, since the label data do not represent truth, models trained with loss functions like mean squared error (MSE) or mean absolute error (MAE) fail to account for its uncertainty. …”
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Unravelling NK cell subset dynamics and specific gene signatures post-ibrutinib therapy in chronic lymphocytic leukaemia via single-cell transcriptomics by Chunlan Liu, Tianjian Ding, Rong Zou, Aili Zhang, Zhengzhuo Zhi, Sili Wang

“…Single-cell transcriptome sequencing was performed, followed by pseudotemporal analysis and functional enrichment to characterize the NK cell subsets. …”
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Comprehensive Evaluation of Chestnut Quality Based on Principal Component and Cluster Analysis by Yanqi YU, Mingyuan YANG, Chunmao LÜ, Shaoci BAI, Qunfang ZHANG, Chenyang ZOU, Han JIANG

“…The first group was ideal for developing functional beverages, the second was suited for kernel processing into canned food, preserved fruit, or chestnut powder for baked goods. …”
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Preparation and Performance of Biomimetic Zebra-Striped Wood-Based Photothermal Evaporative Materials by Zebin Zhao, Wenxuan Wang, Zhichen Ba, Yuze Zhang, Hongbo Xu, Daxin Liang

“…An efficient solar water evaporator is an important strategy for addressing the problem of water shortage. Constructing high-performance solar interfacial evaporators through bionic design has become a crucial approach for performance enhancement. …”
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Integrated mRNA and miRNA Omics Analyses Reveal Transcriptional Regulation of the Tolerance Traits by <i>Aquatica leii</i> in Response to High Temperature by Chao Liu, Jiapeng Li, Lihong Yan, Yuting Zhu, Zikun Li, Chengquan Cao, Yiping Wang

“…This indicates that starting at 28 °C, <i>A. leii</i> needs to maintain normal cellular physiological functions by regulating ligand–receptor binding and signal transduction. …”
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Exploring the key ingredients and mechanisms of Banxia Xiexin decoction for the treatment of polycystic ovary syndrome based on network pharmacology and experimental validation by Bai Hai, Yingying Zhang, Jing Huang, Richard Mprah, Mingming Wang

“…Ovarian pathology, vaginal smears, oxidative stress-related indicators, and hub genes were tested to evaluate its therapeutic effects.Results We identified 3 key ingredients and 99 potential targets for BXD treatment of PCOS. Biological functions of these targets were mainly enriched in oxidative stress, hormone response and apoptosis. …”
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Thai version of ACL return to sports after injury scale translated with cross-cultural adaptation provided the good validation in Thai patients who received ACL reconstruction by Laddawong Teerapat, Vijittrakarnrung Chaiyanun, Woratanarat Patarawan, Saengpetch Nadhaporn

“…The evaluation of return-to-sport readiness should involve a multidisciplinary approach, including surgeons, physiotherapists, and psychologists, to ensure a comprehensive assessment of physical, functional, and psychological factors.…”
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Development and usability of a traditional game simulation module with augmented reality technology (AR-SiGaSTEM) in online learning to strengthen STEM skills among students by Mazlini Adnan, Laili Farhana Md Ibharim, Yoke Seng Wong, I-van Yee, Sukirman

“…The objectives were i) to identify teachers' perspectives on accepting AR-integrated teaching modules for online learning; ii) to develop an AR-SiGaSTEM module and game with content, functions and features suitable for online STEM learning; and iii) to evaluate the module's usability in teaching to enhance STEM skills across the curriculum. …”
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Seismic Vulnerability Assessment of Residential RC Buildings in Yemen Using Incremental Dynamic Analysis (IDA) by Amr Ahmed Radman Ahmed, Linfeng Lu, Bo Li, Wei Bi, Fawziah Mohammed Abdullah Al-Dhubai

“…Traditional buildings constructed in Yemen during the 20th century often lacked adequate seismic protection. …”
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Chinese Family With Knobloch Syndrome Associated With a Novel PAK2 Variant Leading to Reduced Phosphorylation Levels by Liwei Shen, Xiaofei Ye, Xiaocui Wang, Conglei Song, Bin Yang

“…In vitro, a mutant plasmid was constructed and transfected into 293T cells to conduct phosphorylation assays, and phosphorylation levels at Ser141 of PAK2 were assessed. …”
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