Adipose-Derived Mesenchymal Stem Cells Accelerate Diabetic Foot Ulcer Healing by Promoting Macrophage M2 Polarization Through Downregulation of EREG and CSTA by Cao J, Zhang X, Li Z, Zhang S, Guo L, Liu Z, An W, Xu L, Li L, Long X, Yang Y

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Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study by Lieke M. Kuiper, Michelle M. J. Mens, Julia W. Wu, Jaap Goudsmit, Yuan Ma, Liming Liang, Albert Hofman, Trudy Voortman, M. Arfan Ikram, Jeroen G. J. van Rooij, Joyce B. J. van Meurs, Mohsen Ghanbari

“…Next, elastic net models were employed to construct composite microRNA-based aging biomarkers predicting chronological age (mirAge), PhenoAge (mirPA), frailty index (mirFI), and mortality (mirMort). …”
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Performance Study of Non-Contact Membrane Distillation Engineering Prototype for Treatment of Radioactive Wastewater by Bao-lin WANG, De-tao XIAO, Zheng-zhong HE, Xing-feng YANG, Cheng-lin LI

“…A pilot-scale engineering prototype was designed, constructed, and rigorously evaluated to determine its performance metrics. …”
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The impact of chronic illness resources, fear of recurrence, hope, and health locus of control on self-management behaviors in post-stroke patients: a cross-sectional study by Jingxia Cheng, Xiaolian Jiang, Xi Liao, Lili Zhou, Li Qin, Hongying Liu

“…BackgroundStroke often leads to functional impairment in patients and carries a risk of recurrence. …”
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Expression of the IL-18-related gene PTX3 correlates with clinicopathological features and prognosis in glioma patients by Delin Wang, Cuimei Liu, Bohao Sun, Xiaodong Zhang, Yejun Zhou, Zhonglin Hu, Duanzheng Cao, Jing Zhang, Jinfang Xu

“…The functional roles of PTX3 were analyzed through Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Gene Set Enrichment Analysis (GSEA). …”
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Integrative analysis of T cell-mediated tumor killing-related genes reveals KIF11 as a novel therapeutic target in esophageal squamous cell carcinoma by Xinxin Cheng, Huihui Zhao, Zhangwang Li, Liping Yan, Qingjie Min, Qingnan Wu, Qimin Zhan

“…Moreover, we performed functional experiments on KIF11, which ranked as the most significant prognostic risk gene among the 8 TTK-related genes. …”
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Metabolism-Mediated FGF5 Association with Stroke: Based on Mendelian Randomization and Bioinformatics Analysis by Xu C, Xu Y, Gao L, Wang M, Wang G, Wang G

“…The protein-protein interaction (PPI) network of FGF5-related genes was constructed, and various bioinformatics analyses (including functional enrichment, immune infiltration analysis, etc) were conducted to evaluate its functional mechanism.Results: FGF5 was significantly associated with stroke risk (inverse variance weighting method (IVW): odds ratio (OR) = 1.052, 95% confidence interval (CI): 1.021– 1.084, P< 0.01). …”
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Exploring the Role of Bifenthrin in Recurrent Implantation Failure and Pregnancy Loss Through Network Toxicology and Molecular Docking by Shengyuan Jiang, Yixiao Wang, Haiyan Chen, Yuanyuan Teng, Qiaoying Zhu, Kaipeng Xie

“…Candidate targets were identified by intersecting the predicted BF-related targets with the RIF-associated DEGs, followed by functional enrichment analysis using the DAVID and g:Profiler platforms. …”
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Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2 by Ahn G, Yoon HW, Jeong JH, Kim YH, Shin WR, Song MS, Ahn JY

“…Gna Ahn,1,2,* Hyo-Won Yoon,1,* Ju Hwan Jeong,3,4,* Yang-Hoon Kim,1,* Woo-Ri Shin,1,5,6 Min-Suk Song,3 Ji-Young Ahn1 1Department of Microbiology, Chungbuk National University, Cheongju, Republic of Korea; 2Center for Ecology and Environmental Toxicology, Chungbuk National University, Cheongju, Republic of Korea; 3Department of Microbiology, College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea; 4Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, Republic of Korea; 5Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA; 6Department of Animal Bioscience & Integrated Biotechnology, Gyeongsang National University, Jinju, Republic of Korea*These authors contributed equally to this workCorrespondence: Ji-Young Ahn; Min-Suk Song, Tel +82-43-261-2301 ; +82-43-261-3778, Email jyahn@chungbuk.ac.kr; songminsuk@chungbuk.ac.krPurpose: Outer membrane vesicles (OMVs) derived from Gram-negative bacteria naturally serve as a heterologous nano-engineering platform, functioning as effective multi-use nanovesicles for diagnostics, vaccines, and treatments against pathogens. …”
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Crop classification with deep convolutional neural network based on crop feature by Mohamad Reza Gili, Davoud Ashourloo, Hosein Aghighi, Ali Akbar Matkan, Alireza SHakiba

“…In the next step, the functions that were developed as phenological features for crops were applied on the time series of the bands, and for each crop, a feature channel was obtained as the special feature of that crop. …”
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Algorithms of the Method of Statically Admissible Discontinuous Stress Fields (SADSF) – Part II: The Algorithms for Solving Limit Stress Fields Around Isolated Nodes of Stress Disc... by W. Bodaszewski

“…The algorithms enable solving practically any boundary problem that one encounters in constructing 2D statically admissible, discontinuous stress fields, first of all the limit fields. …”
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Discovering new hub genes of dilated cardiomyopathy by Jun‐Yan Zhu, Yu Han, Jing‐Yu Yang, De‐Ping Wang, Li‐Juan Gao, Teng Sun, Yan‐Lin Feng, Zhong‐Mei He, Bin Zhou, Ji‐Min Cao

“…The cDEGs were subjected to Gene Ontology (GO) functional enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment, and the protein–protein interaction (PPI) networks and functional modules were constructed to screen the hub genes. …”
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Harnessing the angiogenic potential of adipose-derived stromal vascular fraction cells with perfusion cell seeding by Gregory Reid, Giulia Cerino, Ludovic Melly, Deborah Fusco, Chunyan Zhang, Oliver Reuthebuch, Giulia Milan, Anna Marsano

“…Abstract Background The rapid formation and long-term maintenance of functional vascular networks are crucial for the success of regenerative therapies. …”
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OncoPSM: an interactive tool for cost-effectiveness analysis using partitioned survival models in oncology trial by Xulong Qiu, Xulong Qiu, Jidi Chen, Jidi Chen, Muting Wang, Kaixin Zheng, Ruixiong Li

“…However, many CEA tools are not specifically tailored to address the intricate cost composition resulting from the complex treatment regimens in oncology trials.MethodsWe extracted data from Kaplan-Meier (KM) curves, reconstructed individual patient data (IPD) using an iterative KM algorithm, and fitted parametric survival functions to the IPD data. Based on these functions, we constructed Partitioned Survival Model (PSM), calculated the probability of each survival state per cycle, and combined these with utility values to compute the effect per cycle and the incremental effect for the experimental group. …”
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Ameliorating Effect of Cordyceps militaris on Antibiotic Intestinal Barrier Injury in Mice by Fengli YU, Jiani WANG, Siqing LIAO, Qi ZHANG, Shenghou WANG, Ze WANG

“…Therefore, the high dose was determined to construct the treatment concentration for antibiotic intestinal injury. …”
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Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA by Paolo Peruzzo, Natascha Bergamin, Martina Bon, Sara Cappelli, Alessandra Longo, Elisa Goina, Cristiana Stuani, Emanuele Buratti, Andrea Dardis

“…Methods A set of constructs expressing 5 different engineered U1 snRNAs was generated. …”
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Organizational Methods of Furniture and Their Aesthetic Relationships in Interior Design by Akram Faraedon Hamaamen, Alwand Dlshad Najib

“…The problem of research lies in the lack of logical vision in the analysis of methods and trends organization furniture and its aesthetic relationship in interior design, which has become contemporary in our time through the introduction of currents and design methods coming without taking into account the suitability of the residential space aesthetically, and the problem of research in its attempt to answer the following questions: How do furniture units contribute to the design treatments of the housing system in embodying the aesthetic and functional dimension in residential interior spaces and upgrading the reality of those spaces? …”
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FACETS OF PROTECTION OF ECONOMIC RIGHTS AND FREEDOMS by Olena Kovalenko, Sergii Vasyliev, Mykola Zhdan

“…This, in turn, highlights the positions of judicial practice and renders the discussion of problems in the protection of economic human rights more constructive and, as a consequence, more effective. Results. …”
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Analysis of the serum proteome profile of wild stump-tailed macaques (Macaca arctoides) seropositive for Zika virus antibodies in Thailand by Pakorn Ruengket, Sittiruk Roytrakul, Daraka Tongthainan, Kobporn Boonnak, Kanokwan Taruyanon, Bencharong Sangkharak, Wirasak Fungfuang

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Single-cell transcriptomic profiling reveals the heterogeneity of epithelial cells in lung adenocarcinoma lymph node metastasis and develops a prognostic signature by Qiuqiao Mu, Qiuqiao Mu, Qiuqiao Mu, Han Zhang, Ying Shi, Mengli Xue, Jingxian Wang, Yun Ding, Lin Tan, Hui Yuan, Xin Li, Xin Li, Daqiang Sun, Daqiang Sun, Daqiang Sun

“…Leveraging these defined cellular subpopulations, we constructed a highly accurate model for prognostication in LUAD, enabling reliable classification of patients based on clinical outcomes. …”
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