Showing 13,561 - 13,580 results of 14,284 for search 'function construction', query time: 0.13s Refine Results
  1. 13561

    Endoplasmic reticulum-localized circular RNA FAM13B restrains nasopharyngeal carcinoma lymphatic metastasis through downregulating XBP1 by Guo-Dong Jia, Si-Yi Xie, Xiao-Yun Li, Liang-Ji Li, Jing Jin, Li-Ting Liu, Xue-Song Sun, Sai-Lan Liu, Qiu-Yan Chen, Lin-Quan Tang, Li Yuan, Hai-Qiang Mai

    Published 2025-07-01
    “…Stable cell lines with circFAM13B overexpression and knockdown were constructed. Functional experiments, including cell invasion, migration, and metastasis assays, were performed in vitro and in vivo. …”
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  2. 13562

    SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1 by Rui Cai, Cong Li, Wenhui Shi, Fenfen Xie, Mengmeng Fan, Hao Zhang, Zhuang Liu, Yuanhua Chen, Qiang Hong

    Published 2025-06-01
    “…Abstract Folliculogenesis is a crucial process for production functional female gametes in mammals. The imbalance of apoptosis and proliferation of ovarian granulosa cells has been identified as an important cause for abnormal folliculogenesis. …”
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  3. 13563

    Graphene coated micro/nano fiber gas sensing mechanism and SF6 decomposition component SO2 detection by Yin ZHANG, Ao CHEN, Wenwen YU, Guozhi ZHANG, Yijie CAI, Xiaoxing ZHANG

    Published 2025-03-01
    “…The optical gas-sensitive response performance of the graphene is analyzed based on the density functional theory. A fiber-loop ring-down (FLRD) gas detection system is constructed,and typical SF6 decomposition component detection experiments are carried out. …”
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    Article
  4. 13564

    Trend analysis of the coupling effect between new urbanization and resources-environment in the Guangdong-Hong Kong-Macao Greater Bay area by Hongyi Dou, Guoqin Zhang

    Published 2025-06-01
    “…Achieving sustainable urbanization necessitates the assurance of the stability and functionality of the urbanization-resource-environment system, but extant studies lack adequate methods for dynamic prediction and analysis of new urbanization characteristics. …”
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    Article
  5. 13565

    Structural network topologies are associated with deep brain stimulation outcomes in Meige syndrome by Bin Liu, Zhiqi Mao, Xinyuan Yan, Hang Yang, Junpeng Xu, Zhebin Feng, Yanyang Zhang, Xinguang Yu

    Published 2024-07-01
    “…Subsequent functional annotation and correlation analyses were also conducted. …”
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    Article
  6. 13566

    Linearity of Structure Kernels in Main-sequence and Subgiant Solar-like Oscillators by Lynn Buchele, Earl P. Bellinger, Saskia Hekker, Sarbani Basu

    Published 2025-01-01
    “…First, we examine what we call the “kernel errors,” which measure how well the mode sensitivity functions can recover known frequency differences between two models. …”
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  7. 13567

    Targeting Sodium Transport Reveals CHP1 Downregulation as a Novel Molecular Feature of Malignant Progression in Clear Cell Renal Cell Carcinoma: Insights from Integrated Multi-Omic... by Yun Wu, Ri-Ting Zhu, Jia-Ru Chen, Xiao-Min Liu, Guo-Liang Huang, Jin-Cheng Zeng, Hong-Bing Yu, Xin Liu, Cui-Fang Han

    Published 2025-07-01
    “…This study aimed to construct a comprehensive cellular and transcriptional landscape of ccRCC, with emphasis on gene expression dynamics during malignant progression. …”
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    Article
  8. 13568

    Study on mechanism of Miao medicine Xinnao Liantong capsule in treatment of myocardial ischemia diseases based on network pharmacology and molecular docking by Yuan Yao, Huan Zhang, Na Zhan, Yong Deng, Jianyong Zhang

    Published 2025-06-01
    “…Functional enrichment analyses were performed using DAVID, and molecular docking was employed to validate core component-target interactions. …”
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    Article
  9. 13569

    Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker by Yannan Hu, Ning Li, Liang Liu, Hao Zhang, Xiang Xue, Xin Shao, Yu Zhang, Xilong Lang

    Published 2019-01-01
    “…The porcine SAN dysfunction model was constructed by electrocoagulation using a surgical electrotome. …”
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    Article
  10. 13570

    Machine learning developed an immune evasion signature for predicting prognosis and immunotherapy benefits in lung adenocarcinoma by Dongxiao Ding, Gang Huang, Liangbin Wang, Ke Shi, Junjie Ying, Wenjun Shang, Li Wang, Chong Zhang, Maofen Jiang, Yaxing Shen

    Published 2025-06-01
    “…Low IRS-based risk score indicated higher level of NK cells, CD8+ T cells, and immune activation-related functions. The C-index of IRS was higher than that of many developed signatures for LUAD and clinical stage. …”
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    Article
  11. 13571

    Insufficient CXCL13 secretion in leprosy foamy macrophages attenuates lymphocyte recruitment and antimicrobial protein production by Chuan Wang, Chuan Wang, Yuan Zhang, Yuan Zhang, Tingting Liu, Tingting Liu, Zihao Mi, Zihao Mi, Peidian Shi, Peidian Shi, Zhenzhen Wang, Zhenzhen Wang, Wenchao Li, Wenchao Li, Honglei Wang, Honglei Wang, Hong Liu, Hong Liu, Furen Zhang, Furen Zhang

    Published 2025-04-01
    “…Significantly, further functional analyses revealed that in vitro treatment with CXCL13 could enhance the expression of CXCR5, thereby promoting lymphocyte migration and secretion of antimicrobial proteins. …”
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    Article
  12. 13572
  13. 13573

    Layered Soil Moisture Retrieval and Agricultural Application Based on Multi-Source Remote Sensing and Vegetation Suppression Technology: A Case Study of Youyi Farm, China by Zhonghe Zhao, Yuyang Li, Kun Liu, Chunsheng Wu, Bowei Yu, Gaohuan Liu, Youxiao Wang

    Published 2025-06-01
    “…Soil moisture dynamics are a key parameter in regulating agricultural productivity and ecosystem functioning. The accurate monitoring and quantitative retrieval of soil moisture play a crucial role in optimizing agricultural water resource management. …”
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    Article
  14. 13574

    A novel identified epithelial ligand-receptor-associated gene signature highlights POPDC3 as a potential therapy target for non-small cell lung cancer by Xiao-Ren Zhu, Jia-Qi Zhu, Qian-Hui Gu, Na Liu, Jing-Jing Lu, Xiao-Hong Li, Yuan-Yuan Liu, Xian Zheng, Min-Bin Chen, Yong Ji

    Published 2025-02-01
    “…Functional assays revealed that POPDC3 knockdown reduced cell proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT), while its overexpression promoted cancerous activities. …”
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    Article
  15. 13575

    Three-Dimensional Real-Scene-Enhanced GNSS/Intelligent Vision Surface Deformation Monitoring System by Yuanrong He, Weijie Yang, Qun Su, Qiuhua He, Hongxin Li, Shuhang Lin, Shaochang Zhu

    Published 2025-04-01
    “…The system integrates GNSS monitoring terminals and multi-source meteorological sensors to accurately capture minute displacements at monitoring points and multi-source Internet of Things (IoT) data, which are then automatically stored in MySQL databases. To enhance the functionality of the system, the visual sensor data are fused with 3D models through streaming media technology, enabling 3D real-scene augmented reality to support dynamic deformation monitoring and visual analysis. …”
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    Article
  16. 13576

    Bionic gene delivery system activates tumor autophagy and immunosuppressive niche to sensitize anti-PD-1 treatment against STK11-mutated lung adenocarcinoma by Zhongquan Song, Qikai Wang, Hongjie Xiong, Jiang Xiao, Zihan Zhou, Tianxiang Li, Qian Sun, Liping Qiu, Yue Tan, Xiaohui Liu, Hui Jiang, Shuhua Han, Xuemei Wang

    Published 2025-04-01
    “…Moreover, STK11@PPCM was also found to improve the sensitivity of cancer cells to αPD1 by increasing the expression of PD-L1, which was confirmed in STK11-mutated NSCLC cell xenografted mouse models, constructed by CRISPR-Cas9 knockout technology. This work demonstrated for the first time that restoration of functional STK11 can effectively reverse ITME and boost αPD1 efficacy in NSCLC, offering a new therapeutic approach for STK11-mutated lung adenocarcinoma in clinic. …”
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  17. 13577
  18. 13578

    Novel oxidative stress- and ferroptosis-related gene prognostic signature for erectile dysfunction by Meijun Liu, Maobin Yu, ZiYang Ma, Zilong Xu, Tao Zhang, Hongsen Zeng, Ze Li, XiYu Dang, Peihai Zhang

    Published 2024-12-01
    “…Additionally, a gene set enrichment analysis (GSEA) was performed to investigate the functions of the key target genes, and the mRNA-miRNA and TF-mRNA regulatory networks were developed to explore the potential regulation of these key genes. …”
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    Article
  19. 13579

    Quality of life and its determinants in women with delayed conception in low-mid socioeconomic neighbourhoods of Northern India: a cross-sectional study by James Kiarie, Sarmila Mazumder, Rita Kabra, Gitau Mburu, Ndema Habib, Ranadip Chowdhury, Neeta Dhabhai, Barsha Gadapani Pathak

    Published 2025-01-01
    “…Background The inability to conceive or delay in conception has negative and multidimensional effects on health and well-being, daily functioning and societal interactions. This study assesses the impact of delayed conception on quality of life (QoL) among Indian women with delayed conception and evaluates the Fertility Quality of Life (FertiQoL) questionnaire’s reliability and construct validity in this population.Methodology A cross-sectional study of 1530 women aged 18–30, who had not conceived over a period of 18 months, was conducted in low-to-mid-socioeconomic neighbourhoods in Delhi, India. …”
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    Article
  20. 13580

    A novel stemness-related lncRNA signature predicts prognosis, immune infiltration and drug sensitivity of clear cell renal cell carcinoma by Jia Liu, Lin Yao, Yong Yang, Jinchao Ma, Ruijian You, Ziyi Yu, Peng Du

    Published 2025-02-01
    “…Enrichment analysis was performed to explore the potential functions of SRmRNAs. Multiple machine learning algorithms were employed to construct a prognostic signature. …”
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    Article