Research progress and strategy of FGF21 for skin wound healing by Shisheng Lin, Lu Tang, Nuo Xu

“…Fibroblast Growth Factor 21 (FGF21), a pivotal member of the fibroblast growth factor family, exhibits multifaceted biological functions, including the modulation of pro-inflammatory cytokines and metabolic regulation. …”
Get full text

Promoter engineering with programmable upstream activating sequences in Aspergillus Niger cell factory by Xiaomei Zheng, Yuting Guo, Meiling Chen, Yudan Lu, Yimou Du, Yu Lei, Ping Zheng, Jibin Sun

“…Results In this study, we identified two functional upstream activation sequences (UAS) located upstream of the core promoters of highly expressed genes in A. niger. …”
Get full text

Security Design for Data Distribution Service Based on Secure Onboard Communication by Fengjun Zhou, Gang Wang, Qun Wang, Yuxing Wang, Jun Wang

“…This method balances security strength and computational overhead through differentiated security processing while considering the ISO 26262 functional safety standard. Compared with the original security plugin, experimental verification in typical communication scenarios demonstrates its superiority in jitter reduction by 35%, latency reduction by 50%, and throughput improvement of approximately 12%, thereby effectively fulfilling the dual requirements of ICV for robust security and high real-time performance.…”
Get full text

LSM2 drives glioma progression through alternative splicing dysregulation: a multi-omics approach to identify a potential therapeutic target by Cao Yang, Chang Ge, Wenjie Zhang, Jingxuan Xu

“…Bioinformatics tools were employed to perform functional enrichment analyses and construct protein–protein interaction (PPI) networks.ResultsLSM2 expression was significantly elevated in gliomas, particularly in GBM and in tumours with 1p/19q non-deletion or IDH1 mutation (p < 0.001). …”
Get full text

The Missing Link: Knowledge Management and the Social Dimension of Business-IT Alignment by Rikard Kloth, Gideon Mekonnen Jonathan

“…In terms of practice, the study guides organizations to strengthen cross-functional collaboration, support sustainable knowledge retention, and align IT capabilities with strategic business objectives. …”
Get full text

Development and Validation of Gene-Based SSR Markers in the Genus Mesembryanthemum by Muhanad Akash, Safwan Shiyab, Mohammed Saleh, Shireen M. Hasan, Mahmoud AbuHussein, Wajdy Al-Awaida

“…The BLASTX analysis successfully assigned functions to 4,623 (79%) of the EST sequences. Among the developed primer sets, 21 primers amplified a total of 65 alleles, with primer PMA79 EST-SSR exhibiting the maximum of six alleles. …”
Get full text

Insights into lncRNA-mediated regulatory networks in Hevea brasiliensis under anthracnose stress by Yanluo Zeng, Tianbin Guo, Liping Feng, Zhuoda Yin, Hongli Luo, Hongyan Yin

“…Additionally, we elucidated the functional roles of HblncRNA29219 and its antisense hbr-miR482a, as well as the miR390-TAS3-ARF pathway, in enhancing anthracnose resistance. …”
Get full text

The FinR-regulated essential gene fprA, encoding ferredoxin NADP+ reductase: Roles in superoxide-mediated stress protection and virulence of Pseudomonas aeruginosa. by Siriwan Boonma, Adisak Romsang, Jintana Duang-Nkern, Sopapan Atichartpongkul, Wachareeporn Trinachartvanit, Paiboon Vattanaviboon, Skorn Mongkolsuk

“…However, the ΔfprA mutant could only be successfully constructed in PAO1 strains containing an extra copy of fprA on a mini-Tn7 vector integrated into the chromosome or carrying it on a temperature-sensitive plasmid. …”
Get full text

Evaluating the psychometric properties of the 24-item and 12-item real relationship inventory-client forms. by Alberto Stefana, Paolo Fusar-Poli, Eduard Vieta, Eric A Youngstrom

“…Both versions showed functionally identical reliability and factor structure when therapy is online vs. in-person. …”
Get full text

Novel cuproptosis-related lncRNAs risk model to predicting prognosis and guiding immunotherapy for OSCC patients by Lingbo Kong, Chenfei Wang, Xiaohui Lu, Qianqi Zhu, Yihua Song, Xingmei Feng

“…The two risk groups differed significantly in immune functions, drug sensitivity, and overall survival. …”
Get full text

Therapeutic limitations of oncolytic VSVd51-mediated miR-199a-5p delivery in triple negative breast cancer models by Guillaume St-Cyr, Lauren Daniel, Hugo Giguère, Rayanna Birtch, Carolina S. Ilkow, Lee-Hwa Tai

“…We demonstrate that both viral constructs are functional and capable of overexpressing mature miR-199a-5p. …”
Get full text

Graph-theoretical model of global human interactome reveals enhanced long-range communicability in cancer networks. by Evgeny Gladilin

“…Our ontological analysis shows that these genes are associated with enhanced cell division, DNA replication, stress response, and other cellular functions and processes typically upregulated in cancer. …”
Get full text

Industrial heritage and urban renewal: a quantitative study and optimization strategies for Chengdu East Suburb Memory by Jun Xia, ShaoQing Wang, Ai Cheng

“…While cultural and spatial factors require deeper integration, technological innovations should be leveraged to enhance functional performance. These insights provide policymakers and urban planners with actionable strategies to balance social, economic, and cultural benefits, advancing sustainable urban development goals. …”
Get full text

FAULT SYSTEMS IN THE UPPER CRUST OF THE CENTRAL ASIAN FOLDING BELT by V. S. Burtman

“…Among them, a significant number of faults were functioning during two or more epochs of orogenic deformations. …”
Get full text

The Impact of Geometric Shapes on Modern European Sculpture "An Analytical Study" by Naseer Abdul Karim Abboud

“…A lot of artistic movements appeared, especially in the twentieth century, and the content of these movements was purely geometric, plastic, looking for everything new and unique in the modern era, and starting to use these geometric shapes in the plastic arts and searching for art that is not devoid of the functional side and in line with that policy as well. …”
Get full text

Atomistic-Level Insights into MgO and Na₂O Modifications of Molten Aluminosilicate Slag: A Molecular Dynamics Research on Structural Evolution and Properties by Chunhe Jiang, Bo Liu, Jianliang Zhang, Kejiang Li

“…Molecular dynamics simulations were employed to systematically investigate the synergistic effects of Na₂O and MgO on the atomistic-scale structural evolution and properties of CaO–SiO₂–Al₂O₃-based slags. By constructing slag models with varying Na₂O/MgO ratios, the variations in pair distribution functions, oxygen structural units, coordination environments, diffusion coefficients, and viscosity were analyzed in detail. …”
Get full text

EG-DPoS: Optimized DPoS Consensus Algorithm Based on Evolutionary Game by LIU Yong, DENG Xiaohong, LIU Lihui, SHI Yiran, ZHANG Li

“…The credit mechanism is introduced to construct the node voting incentive model, and the credit value reward is given according to the voting situation of nodes, which effectively improves the voting enthusiasm of nodes. …”
Get full text

Test–retest reliability and validity in lower limb proprioception tests using image capture technique in healthy adults by Aisuke Takahashi, Hikaru Kawana, Katsuhiro Furukawa

“…Quantitative proprioception assessments such as threshold to detect passive motion (TDPM) and joint position sense (JPS) help determine the severity of functional impairments and evaluate treatment efficacy. …”
Get full text

Naoxintong Is Involved in the Coagulation Regulation of Warfarin Through the MAPK Pathway by Luo X, Chen L, Xu J, Li J

“…GO and KEGG were used for functional analysis. The effect of NXT on warfarin anticoagulation was then tested in rats by analyzing coagulation factors in blood before and after drug administration. …”
Get full text

CONSIDERATIONS FOR THE DEVELOPMENT OF A DEVICE FOR THE DECOMMISSIONING OF THE HORIZONTAL FUEL CHANNELS IN THECANDU 6 NUCLEAR REACTOR. PART 11 - PRESENTATION OF THE CUTTING AND EXTR... by Constantin D. STANESCU, Constantin POPESCU, Gabi ROSCA FARTAT

“…This paper presents a constructive solution proposed by the authors in order to achieve of a cutting and extracting device for the decommissioning of the horizontal fuel channels in the CANDU 6 nuclear reactor. …”
Get full text