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13381
Predicting depression in healthy young adults: A machine learning approach using longitudinal neuroimaging data
Published 2025-07-01“…This study aimed to develop predictive models for depression in young adults using machine learning (ML) techniques and longitudinal data from the Beck Depression Inventory, structural MRI (sMRI), and resting-state functional MRI (rs-fMRI). Feature selection methods, including the least absolute shrinkage and selection operator (LASSO), Boruta, and VSURF, were applied to identify MRI features associated with depression. …”
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13382
Predicting depression risk in middle-aged and elderly adults in China using CNN-BiLSTM-Attention mechanism and LSTM+SHAP framework
Published 2025-08-01“…SHAP analysis for the LSTM and CNN-BiLSTM-Attention models identified health status and functionality as key factors influencing depression risk in middle-aged and elderly individuals, with pain, gender, sleep duration, and IADL (Instrumental Activities of Daily Living) being the most significant factors. …”
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13383
A toolkit for facilitating markerless integration of expression cassettes in Komagataella phaffii via CRISPR/Cas9
Published 2025-05-01“…Abstract Background The yeast Komagataella phaffii (formerly known as Pichia pastoris) has been widely used for functional expression of recombinant proteins, including plant and animal food proteins. …”
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13384
Tactile Communism: Keti Chukhrov’s Post-Soviet Dramatic Works and the Legacy of Soviet Defectology
Published 2023-12-01“…I argue that, while descriptions of violence, physiological functions, and abject poverty are common for post-Soviet art, in Chukhrov’s work these elements perform radically different task than in the pessimistic and de-ideologized chernukha, or the style of grim realism. …”
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13385
Identification and verification of immune and oxidative stress-related diagnostic indicators for malignant lung nodules through WGCNA and machine learning
Published 2025-07-01“…A protein–protein interaction (PPI) network was constructed and hub genes were extracted using 12 centrality-based algorithms in the CytoHubba plugin. …”
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13386
Cognitive prehabilitation for geriatric patients undergoing elective surgery: a PRISMA-P-compliant protocol for a systematic review
Published 2022-07-01“…This comprehensive systematic review will assess the effectiveness and safety of cognitive prehabilitation programmes prior to surgery on cognitive functional capacity and postoperative cognitive outcomes in geriatric patients undergoing elective surgery.Methods and analysis This protocol was prepared using the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. …”
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13387
Cloning, expression and purification of outer membrane protein PorA of Neisseria meningitidis serogroup B
Published 2011-11-01“…PorA is a major component of the outer membrane of N. meningitidis and functions as a cationic porin. This study aimed to clone and determine the expression of PorA. …”
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13388
Identified VCAM1 as prognostic gene in gastric cancer by co-expression network analysis
Published 2024-12-01“…Co‐expression gene modules were constructed via Weighted Gene Co‐Expression Network Analysis (WGCNA), followed by deciphering gene functions and protein–protein interaction networks within significantly associated modules. …”
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13389
Single-Cell RNA Sequencing Reveals an Atlas of Meihua Pig Testis Cells
Published 2025-03-01“…Pseudo-timing analysis showed that myoid cells and stromal cells originated from common progenitors in Meihua pigs. Functional enrichment analysis revealed that the differentially expressed genes (DEGs) in testicular somatic cells were enriched in the pathways of Ribosome, Oxidative phosphorylation, Protein processing in endoplasmic reticulum, Retrograde endocannabinoid signaling, Cellular senescence and Insulin signaling. …”
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13390
Visualizing the enteric nervous system using genetically engineered double reporter mice: Comparison with immunofluorescence.
Published 2017-01-01“…<h4>Background and aims</h4>The enteric nervous system (ENS) plays a crucial role in the control of gastrointestinal motility, secretion and absorption functions. Immunohistochemistry has been widely used to visualize neurons of the ENS for more than two decades. …”
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13391
Cross-sectional association between hs-CRP/HDL-C ratio and physical frailty among middle-aged and older adults: findings from a population-based study
Published 2025-05-01“…BackgroundFrailty, characterized by functional decline and disability, is an emerging public health concern in aging populations. …”
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13392
Minimally Invasive Three-Column Fixation for Displaced Intra-Articular Calcaneal Fractures
Published 2024-12-01“…Category: Trauma; Hindfoot Introduction/Purpose: Calcaneus can be morphologically and biomechanically constructed of medial column, lateral column and a connecting beam acting as transverse column. …”
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13393
Characterization of key genes and immune cell infiltration associated with endometriosis through integrating bioinformatics and experimental analyses
Published 2025-03-01“…The protein–protein network (PPI) was constructed. Four machine learning methods, including LASSO, SVM-RFE, random forest, and Boruta, were applied to identify the key genes associated with EM. …”
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13394
Micro-Yizkor and Hasidic Memory: A Post-Holocaust Letter from the Margins
Published 2025-07-01“…Engaging scholarship by Michal Shaul, Lior Becker, Gershon Greenberg, and others, the analysis demonstrates how citation, far from being a passive act, functions here as an instrument of resistance, memory, and redemptive reconstruction. …”
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13395
A multi-type programmed cell death gene signature predicts survival and reveals therapeutic targets in osteosarcoma
Published 2025-06-01“…Methods Transcriptomic data from GEO and clinical data from TARGET were analyzed. Functional enrichment, N6-methyladenosine (m6A)-related genes analysis and immune checkpoint analyses were performed. …”
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13396
Efficient and Composable Masked AES S-Box Designs Using Optimized Inverters
Published 2024-12-01“…In this paper, we present a F28 inverter that achieves the optimal multiplicative depth of three, and use it to construct a more efficient trivially composable masked implementation of the AES S-Box. …”
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13397
Artificial Intelligence and Moral intelligence
Published 2008-07-01“…If our theoretical hypothesis about a specific moral intelligence, necessary for the implementation of an artificial moral conduct, is correct, then some theoretical and technical issues appear, but the following working hypotheses are possible: structural, functional and behavioural. The future of human and/or artificial morality is to be anticipated.…”
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13398
Beyond autonomous regions: measuring communal self-governance
Published 2025-07-01“…This may occur when a country’s administrative units are drawn around ethnic, religious, or linguistic settlement areas, and those administrative units also benefit from meaningful autonomy. An index constructed with the help of the QGIS software spatial join functions, which allowed for the quantification of the degree of overlap between the regional minorities’ settlement areas and the ADM01 units (https://gadm.org/), shows that minority self-government has, indeed, the same pacifying effect as other measures of political equality and minority protective policies. …”
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13399
Models of early stages of design of trunk-route passenger airplanes with taking families into account
Published 2022-11-01“…The values of these reserves should be substantiated based on the evaluation of future functioning of the whole created airplane family within the airline fleet. …”
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13400
Virtual surgical planning in soft tissue reconstruction for oral cancer
Published 2024-01-01“…In a patient with locally advanced left buccal mucosa cancer, reconstruction of the postoperative defect was successful without local complications after reconstruction. Good functional and aesthetic results were obtained. The patient was observed for 2 years without signs of disease. …”
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