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13281
MitCOM-based prognostic model identifies GLUD1 as a key suppressor of glioblastoma growth and invasion through regulation of mitochondrial structure and metabolism
Published 2025-06-01“…Results GLUD1 expression was downregulated in GBM and associated with poor survival. Functional studies showed that GLUD1 regulates mitochondrial crista organisation and metabolic reprogramming. …”
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13282
Identification and validation of diagnostic biomarkers for temporal lobe epilepsy related to ferroptosis and potential therapeutic targets
Published 2025-02-01“…A nomogram was constructed using these markers, and enrichment analyses revealed their links to T-cell activation, allograft rejection, and glial differentiation. …”
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13283
Comprehensive analysis of ESCRT transcriptome-associated signatures and identification of the regulatory role of LMO7-AS1 in osteosarcoma
Published 2025-01-01“…Finally, LMO7-AS1 was chosen for functional experimental validation. The knockdown of LMO7-AS1 suppressed the malignant progression of OS cells. …”
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13284
Advanced Interpretation of Bullet-Affected Chest X-Rays Using Deep Transfer Learning
Published 2025-06-01“…Our research examined various deep learning models that functioned either as classifiers or as object detectors to develop effective solutions for ballistic trauma detection in X-ray images. …”
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13285
Identification of fatty acid anabolism patterns to predict prognosis and immunotherapy response in gastric cancer
Published 2025-01-01“…Importantly, a distinctive FA-score was constructed through the principal component analysis to quantify the characteristics of fatty acid anabolism in each GC patient. …”
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13286
An approach to predicting the properties of software vulnerabilities
Published 2024-11-01“…Analytical linear functions were obtained that approximate the average values of the instantaneous intensity of changes in the values of basic metrics within a quarter of the year, starting from January 1, 2017. …”
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13287
Empowering Stroke Survivors: developing a patient version of guidelines to facilitate patient rehabilitation nursing of stroke patients with limb dysfunction in China
Published 2025-01-01“…The final guideline encompassed five themes: disease knowledge, functional assessment, symptom prevention and nursing, rehabilitation training, and traditional Chinese medicine nursing - a specialized approach integrating traditional Chinese medicine principles with modern nursing practices, including 26 recommendations.ConclusionThis patient-centered guideline, grounded in a robust scientific framework and tailored to patient needs, serves as a valuable reference for the RN of stroke patients with limb dysfunction. …”
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13288
A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its genetic relationship with cholesterol metabolism
Published 2025-01-01“…To explore the biological pathways and functions underlying chronic inflammation, we conducted a genome-wide association study (GWAS) and several post-GWAS analyses of the hsCRP levels. …”
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13289
Versatile clinical application of radial artery perforator flap for hand and wrist reconstruction
Published 2023-01-01“…RAPF provides suitable skin coverage with elastic subcutaneous tissue thus enabling the protection of exposed or damaged functional structures and their simultaneous repair. …”
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13290
Super-enhancer-hijacking RBBP7 potentiates metastasis and stemness of breast cancer via recruiting NuRD complex subunit LSD1
Published 2025-03-01“…Tail vein injection models were constructed to assess the in vivo metastatic efficiency of BCa cells. …”
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13291
Chronic fatigue syndromes: real illnesses that people can recover from
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13292
Single-cell multi-omics analysis identifies SPP1+ macrophages as key drivers of ferroptosis-mediated fibrosis in ligamentum flavum hypertrophy
Published 2025-02-01“…Subcluster analysis of fibroblasts revealed functional heterogeneity among distinct subpopulations, highlighting the functional characteristics and the metabolic dynamics of fibroblast with a high ferroptosis score (High Ferro-score FB). …”
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13293
NAP1L5 in acute myeloid leukemia: a prognostic biomarker and potential therapeutic target
Published 2025-07-01“…Furthermore, we constructed an interaction network and predictive model for NAP1L5, complemented by an assessment of its role in immune infiltration and drug sensitivity. …”
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13294
Specific features of cognitive skill development in athletes of situational sports
Published 2025-06-01“…The results of the discriminant analysis show that, when constructing a linear discriminant analysis (LDA) model with three classes (football, judo, taekwondo), two discriminant functions were identified, explaining 62% (LD1) and 38% (LD2) of the variance between the groups, respectively. …”
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13295
Validation of the PsAID-12 Russian questionnaire in patients with psoriatic arthritis
Published 2022-05-01“…A moderate and strong bond was considered r≥0.30. Constructive validity was assessed by the method of “known groups” and factor analysis. …”
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13296
CLINICAL ASPECTS OF PATIENTS WITH NON-REMOVABLE PROSTHESIS RESULTS OF ZRO2 COATED PROSTHESES
Published 2018-03-01“…Groups include 100 patients of age 20-55 years, where existing orthopedic constructions are made of dental alloys of non-precious (basic) metals, as well as control group of patients for who orthopedic constructions based on zirconium dioxide is made. …”
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13297
The bioinformatics analysis and experimental validation of the carcinogenic role of EXO1 in lung adenocarcinoma
Published 2024-12-01“…Subsequently, a protein-protein interaction (PPI) network was constructed using differentially expressed genes (DEGs) to identify pivotal genes. …”
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13298
Spatial Variation in Food Web Structures, Energy Flows, and System Attributes Along the Pearl River and Their Indications of Protection and Restoration
Published 2025-02-01“…The most diverse functional groups were found in island and estuarine zones due to their heterogeneous habitats (e.g., high submerged vegetation coverage and the transition area between fresh and brackish water). …”
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13299
Prognostic value and immunotherapy analysis of immune cell-related genes in laryngeal cancer
Published 2025-04-01“…Key genes were identified through the intersection of differentially expressed genes (DEGs) between normal and LC samples and module genes derived from weighted gene co-expression network analysis (WGCNA), followed by functional enrichment analysis. The prognostic risk model was constructed using univariate Cox and Least Absolute Shrinkage and Selection Operator (LASSO) analyses. …”
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13300
Comprehensive Analysis of Programmed Cell Death-Related Genes in Diagnosis and Synovitis During Osteoarthritis Development: Based on Bulk and Single-Cell RNA Sequencing Data
Published 2025-01-01“…A diagnostic model for OA was constructed based on the expression levels of Hub PCD-DEGs. …”
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