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13221
A coagulation-related long non-coding RNA signature to predict prognosis and immune features of breast cancer
Published 2025-05-01“…Using transcriptomic data from 1,045 BC patients in TCGA, we identified CRG-associated lncRNAs via coexpression analysis (Pearson |R|> 0.4, p < 0.001) and constructed a prognostic model through univariate Cox analysis, LASSO regression with tenfold cross-validation (λ = 0.05), and multivariate Cox analysis. …”
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13222
In-SITE: In situ soil topological examination platform for hydration state, volumetric density and carbon stocks assessment
Published 2024-12-01“…The research outlines the use of Room Temperature Ionic Liquid (RTIL) functionalized sensors and the development of a portable hardware system for field deployment. …”
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13223
Restructuring Non-teaching Hospitals into Teaching Hospitals in Iran: Component Change in General Hospitals
Published 2024-09-01“…This study had some implications including highlighting the need to formulate protocols for restructuring non-teaching hospitals into teaching hospitals or constructing new teaching hospitals, classifying teaching hospitals and clarifying their differences, focusing on the teaching mission in hospitals, and reviewing and updating the integration of medical education in providing health services.…”
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13224
Bioengineered cardiovascular bypass grafts via in vivo self-assembly of scaffold-guided tubular tissue in rats
Published 2025-08-01“…Here, we present a scaffold-guided in vivo tubular tissue self-assembly strategy to rapidly engineer functional cardiovascular bypass grafts. Using 3D-printed biodegradable scaffolds implanted subcutaneously in SD rats, we generated bioengineered tubular vascular constructs (BTCs) rich in host cells and extracellular matrix within 2 weeks. …”
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13225
Development of a highly efficient p-coumaric acid-responsive biosensor in Saccharomyces cerevisiae
Published 2025-12-01“…This biosensor was constructed by expressing the BsPadR repressor from Bacillus subtilis and engineering hybrid promoters. …”
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13226
Artificial chromosome reorganization reveals high plasticity of the budding and fission yeast genomes
Published 2025-07-01“…Results Using unicellular yeast models of both Saccharomyces cerevisiae and Schizosaccharomyces pombe, we deliberately construct dozens of single-chromosome strains with different chromosome architectures. …”
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13227
Precise Pt-skin manipulation of strain and ligand effects for oxygen reduction
Published 2025-09-01“…Herein, we develop a Pt-skin engineering strategy to construct a family of dendrite-like porous PtCu@PtnL nanospheres (NSs) with precisely controlled Pt-skin layers by adjusting the reducibility of Cu ions. …”
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13228
Hazard assessment of compound drought and heat events on summer maize from agricultural and meteorological perspectives
Published 2025-05-01“…As the impact of compound drought and heat events on agricultural production continues to intensity, this study constructed a hazard assessment model using a compound magnitude index improved by pre-factors and joint probabilities fitted with optimal copula functions. …”
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13229
A bi-subpopulation coevolutionary immune algorithm for multi-objective combinatorial optimization in multi-UAV task allocation
Published 2025-01-01“…Second, the desired solution of real missions often needs to satisfy multiple objective functions, or a set of solutions for decision-making. …”
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13230
Robust Stick‐and‐Play Photothermal Icephobic Film with Bioinspired Insulation Cells
Published 2025-05-01“…This study provides a designing strategy of robust and efficient photothermal films constructed from THMC and finds flexible use for diverse surfaces.…”
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13231
The Structural Design and Optimization of a Railway Fastener Nut Disassembly and Assembly Machine
Published 2025-04-01“…Both the mechanical structure’s reliability and functionality meet the design objectives and requirements, demonstrating significant application value for promoting the intelligent maintenance of railways.…”
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13232
Si/Pyrex glass and poly(dimethylsiloxane)-based microfluidic devices with integrated heating elements for TiO2 nanoparticle synthesis
Published 2025-06-01“…Comparative analysis reveals that the PDMS microreactor exhibits superior functionality when compared to the silicon/Pyrex glass counterpart. …”
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13233
Dendritic Cell Activity Driven by Recombinant Mycobacterium bovis BCG Producing Human IL-18, in Healthy BCG Vaccinated Adults
Published 2015-01-01“…Tuberculosis remains an enormous global burden, despite wide vaccination coverage with the Bacillus Calmette-Guérin (BCG), the only vaccine available against this disease, indicating that BCG-driven immunity is insufficient to protect the human population against tuberculosis. In this study we constructed recombinant BCG producing human IL-18 (rBCGhIL-18) and investigated whether human IL-18 produced by rBCGhIL-18 modulates DC functions and enhances Th1 responses to mycobacterial antigens in humans. …”
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13234
Apple leaf disease severity grading based on deep learning and the DRL-Watershed algorithm
Published 2025-08-01“…Then, we combined the Dice Loss and Focal Loss functions to construct an enhanced HRNet based semantic segmentation model for pixel-level segmentation of both apple leaf and diseased regions. …”
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13235
Biocomposite microfibrous/hydrogel scaffold containing sulfated alginate hydrogel for acceleration of chondrogenic differentiation
Published 2025-08-01“…PCL fibers were prepared using centrifugal spinning and functionalized with alginate sulfate chains. Then, to integrate the fibers and construct the composite scaffold, these fibers were mixed with different hydrogel binders including alginate sulfate, gelatin and a combination of both. …”
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13236
Genomic, Evolutionary, and Pathogenic Characterization of a New <i>Polerovirus</i> in Traditional Chinese Medicine <i>Viola philippica</i>
Published 2025-01-01“…An infectious cDNA clone of VPPV was successfully constructed and shown to infect <i>Nicotiana benthamiana</i>. …”
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13237
The extraction of effective components and an antioxidant activity study of Tulipa edulis
Published 2024-01-01“…This study provides reference value for the further development and application of T. edulis and the development of functional food.…”
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13238
Integrated ecological quality assessment of the sea area adjacent to the Yellow River estuary under multiple pollutants
Published 2025-02-01“…Estuaries are increasingly threatened by pollutants derived from human activities, which severely impair their water quality, biodiversity, and ecological functions. Therefore, within this context, it is essential to conduct comprehensive and scientifically rigorous assessments of estuarine ecological quality. …”
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13239
Design and optimization of an open personalized human-computer interaction system for New Year Painting based on the learner's model
Published 2024-12-01“…Based on the smart learning model, the functional modules of the human-computer interaction teaching system are analyzed and designed in detail, including online learning, online testing and educational information. …”
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13240
Evolution of cetacean-specific conserved non-coding elements suggests their role in the limb changes during secondary aquatic adaptation
Published 2025-07-01“…Conclusions In summary, our study supports the functional role of CNE sequence divergence and the complex mechanisms underlying limb morphology changes in cetaceans.…”
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