A Domain-Specific Pretrained Model for Detecting Malignant and Premalignant Ocular Surface Tumors: A Multicenter Model Development and Evaluation Study by Zhongwen Li, Yangyang Wang, Wei Qiang, Xuefang Wu, Yanyan Zhang, Yiyuan Gu, Kuan Chen, Donghua Qi, Liheng Xiu, Yunduan Sun, Daoyuan Li, Yahui Xi, Shiqi Yin, Feng Wen, Mingmin Zhu, Yi Shao, Jiewei Jiang, Wei Chen, Guohai Wu

“…Our proposed model has high potential to enhance the early detection and treatment of malignant and premalignant OSTs, thereby reducing cancer-related mortality and optimizing functional outcomes.…”
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EM Database v1.0: A benchmark informatics platform for data-driven discovery of energetic materials by Xin Huang, Wen Qian, Jian Liu, Jun-hong Zhou, Chao-yang Zhang

“…The QC data in the database were extracted via ground-state density functional calculations using the B3LYP/6-31G(d,p) method. …”
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Oxidation Mechanisms of Electrolyte and Fire Gas Generation Laws During a Lithium-Ion Battery Thermal Runaway by Yao Tian, Xia Zhang, Qing Xia, Zhaoyang Chen

“…During the sequence of oxidation reactions, the -COH functional group emerged as the most critical intermediate product. …”
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Exploring the molecular mechanisms of subarachnoid hemorrhage and potential therapeutic targets: insights from bioinformatics and drug prediction by Yi Liu, Yang Zhang, Huan Wei, Li Wang, Lishang Liao

“…Through bioinformatics analysis, we constructed a protein-protein interaction (PPI) network and performed functional enrichment analysis using gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) databases. …”
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Boosting High-Rate Lithium Metal Batteries by Using Ether-Based Gel Polymer Electrolyte by Chenchen Zhang, Zuohang Li, Su Wang, Chen Li, Yuchang Si, Yue Ma, Dawei Song, Hongzhou Zhang, Xixi Shi, Lianqi Zhang

“…Density functional theory calculations show that the binding energies of Li+/DFOB− with a polymer matrix are much higher than those of the liquid electrolyte, which is conducive to the release and the rapid transfer of more Li ions. 7Li solid-state nuclear magnetic resonance exhibits a similar result; the higher frequency observed after cycling indicates a larger electron density variation and greater mobility of Li ions. …”
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Exploration of the mechanism of 5-Methylcytosine promoting the progression of hepatocellular carcinoma by Qiyao Zhang, Zhen Cao, Yuting He, Ziwen Liu, Wenzhi Guo

“…5-Methylcytosine (m5C) is a ubiquitous RNA modification that is closely related to various cellular functions. However, no studies have comprehensively demonstrated the role of m5C in hepatocellular carcinoma (HCC) progression. …”
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MODELING THE RELATIONS BETWEEN RELIGIOSITY, ETHNIC AND CONFESSIONAL IDENTITY IN THE CONTEXT OF SOCIETAL SECURITY IN RUSSIA’S ASIAN BORDERLANDS by Svetlana G. Maximova, Daria A. Omelchenko, Oksana E. Noyanzina

“…Statistical modeling shows that security is also a multidimensional construct, having different facets, and the salience of these facets depends on the importance of the religiosity dimension. …”
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Hsa_circ_0001756 drives gastric cancer glycolysis by increasing the expression and stability of PGK1 mRNA by Long Qian, Long Qian, Long Qian, Luman Wang, Hao Chen, Song Wang, Song Wang, Yinfen Hou, Li Xu, Li Xu, Yabin Xia, Yabin Xia, Maoqi Xu, Xiaoxu Huang, Xiaoxu Huang

“…The proliferation and migration of hsa_circ_0001756-expressing cells in vitro were assessed by functional experiments. Hsa_circ_0001756 was found to not only promote the expression and stability of PGK1 by binding with polypyrimidine tract-binding protein 1 (PTBP1) but also promote glycolysis through the miR-185-3P/PGK1 pathway. …”
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Injectable hydrogels for Fenton-like Mn2+/Fe2+ delivery with enhanced chemodynamic therapy prevent osteosarcoma recurrence and promote wound healing after excision surgery by Lutong Wang, Haoyu Guo, Weiyue Zhang, Xingyin Li, Ziliang Su, Xin Huang

“…The present anti-tumor treatments could inhibit normal tissues, resulting in difficulties in surgical wound healing. In this study, we constructed an injectable hydrogel as a platform to co-deliver MnO2 nanoparticles and ferrocene Fc, termed as (MnO2/Fc)@PLGA for osteosarcoma treatment and wound healing after excision. …”
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The Proangiogenic Potential of Rat Adipose-Derived Stromal Cells with and without Cell-Sheet Induction: A Comparative Study by Xiaoru Xu, Shuang Song, Xiangdong Liu, Yuchao Zhou, Shaojie Shi, Guoqiang Zhao, Xingxing Wang, Xutao Chen, Wenshuang Zhao, Sijia Zhang, Wei Ma, Yingliang Song

“…A functional vasculature for survival remains a challenge for tissue regeneration, which is indispensable for oxygen and nutrient supply. …”
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Puerarin pretreatment provides protection against myocardial ischemia/reperfusion injury via inhibiting excessive autophagy and apoptosis by modulation of HES1 by Yong Yuan, Songqing Lai, Tie Hu, Fajia Hu, Chenchao Zou, Xiuqi Wang, Ming Fang, Jichun Liu, Huang Huang

“…In vivo MIRI and in vitro anoxia/reoxygenation (A/R) models were constructed. The results demonstrated that Pue pretreatment effectively alleviated MIRI, as manifested by diminishing the levels of serum CK-MB and LDH, mitigating the extent of myocardial infarction and enhancing cardiac functionality. …”
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Blocking copper transporter protein-dependent drug efflux with albumin-encapsulated Pt(IV) for synergistically enhanced chemo-immunotherapy by Man Fang, Lei Cao, Zhao Zhang, Zhen Yu, Yue Shen, Jieqi Chen, Juan Chen, Yue-Qin Li, Zhaoqian Liu, Yingcai Meng, Haihua Xiao, Qiang Qu, Ji-Ye Yin, Xiang-Ping Li

“…While numerous studies concentrate on their functional modifications and targeted delivery, tumor-induced platinum resistance is frequently overlooked. …”
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Exploring pesticide risk in autism via integrative machine learning and network toxicology by Ling Qi, Jingran Yang, Qiao Niu, Jianan Li

“…Each combination of 1–23 targets was used to construct predictive models using eight different machine learning algorithms. …”
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Chemical Pollutant Exposure in Neurodevelopmental Disorders: Integrating Toxicogenomic and Transcriptomic Evidence to Elucidate Shared Biological Mechanisms and Developmental Signa... by Xuping Gao, Xinyue Wang, Xiangyu Zheng, Yilu Zhao, Ning Wang, Suhua Chang, Li Yang

“…Using the Comparative Toxicogenomics Database (CTD), we constructed chemical exposome frameworks for seven neurodevelopmental disorders (NDDs) and identified chemical pollutants of epidemiological concern, including air pollutants (n = 8), toxic elements (n = 14), pesticides and related compounds (n = 18), synthetic organic chemicals (n = 16), and solvents (n = 5). …”
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Development and validation of the Fall Risk Assessment Scale for patients in rehabilitation hospitals: A methodological study by Shoeleh Rahimi, Hamid Reza Khankeh, Abbas Ebadi, Batol Mohammadian, Narges Arsalani, Masoud Fallahi‐Khoshknab, Nazila Akbarfahimi, Elham Loni

“…Results Fall was significantly associated with disease diagnosis, used medications, history of fall, cognitive impairments, and three items of the Functional Independence Measure (toilet transfer, bed transfer, and shoer transfer). …”
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Availability of support and quality of life of parents of children with autism spectrum disorders in pandemic conditions by Kovačić Zoran M., Cvijetić-Vukčević Marija M., Nikolić Gordana I.

“…Due to the COVID-19 pandemic, children with autism spectrum disorders and their parents faced numerous challenges related to health care, education and daily functioning, while available support was limited and often inadequate. …”
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Inhibitory Effects of Bovine Lactoferricin-Lactoferrampin on Senecavirus A and Foot-and-Mouth Disease Virus with Recombinant Lactobacillus Oral Treatment in Mice by Wenyue Zhao, Senhao Zhang, Ling Sui, Xiaona Wang, Jiaxuan Li, Wen Cui, Yanping Jiang, Xinyuan Qiao, Lijie Tang

“…Studies have shown that lactoferrin peptides can inhibit the replication of various viruses and enhance the body’s immune functions. Based on this, in the present study, we aimed to investigate the effects of bovine lactoferricin-lactoferrampin (LFCA) on replicating FMDV and SVA and to analyze its role in the cellular antioxidant response caused by viral infection; in addition, we fed mice with constructed recombinant <i>Lactobacillus reuteri</i> expressing LFCA. …”
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The Development of an Air Suction Precision Seed-Metering Device for Rice Plot Breeding by Wei Qin, Yuwu Li, Cheng Qian, Zhuorong Fan, Daoqing Yan, Guo Zou, Siqian Liu, Zaiman Wang, Ying Zang, Minghua Zhang

“…To address the lack of specialized seeding equipment and low manual seeding efficiency in rice plot breeding, this study developed an air suction precision seed-metering device for rice plot breeding, featuring automatic seed-switching and seed-clearing functions controlled by an STM32 microcontroller. Firstly, based on morphological analysis and MATLAB image processing, an active contour method was used to construct a suction hole model. …”
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A vegetation strategy to balance the hazardous level of microplastics in the land–sea interface through rhizosphere remediation by Weifeng Ruan, Yanqin Peng, Xi Ling, Bailun Yu, Yiping Tai, Nora Fung-Yee Tam, Yunv Dai, Yang Yang

“…This primarily pertains to the following aspects: direct and indirect effects of MPs on plants (including combined pollution), which included growth and development; nutrient intake; and physiological, biochemical, and genetic functions. The growth environments and physiological structures of aquatic plants and terrestrial plants differed, resulted in a greater potential for the root systems of aquatic plants to capture MPs. …”
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Microbial succinate promotes the response to metformin by upregulating secretory immunoglobulin a in intestinal immunity by Ying Zhang, Aiting Wang, Wei Zhao, Jia’an Qin, Yu Zhang, Bing Liu, Chengcheng Yao, Jianglan Long, Mingxia Yuan, Dan Yan

“…In conclusion, we demonstrated that upregulated SIgA, which could be regulated by succinate, was functionally involved in metformin response through its influence on immune cell-mediated inflammation and insulin resistance. …”
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