CDKN2A, a key gene in copper-induced cell death model, influencing melanoma invasion and apoptosis by Jing Li, Xi Yang, Cunli Yin, Siru Li, Yan Xu, Bin Liu

“…However, the exact role of cuproptosis in SKCM development and progression is unknown, and painting a clear picture of its functions in SKCM is fraught with challenges. A more systematic investigation is justified. …”
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A low-complexity linker as a driver of intra- and intermolecular interactions in DNAJB chaperones by Billy Hobbs, Noor Limmer, Felipe Ossa, Ella Knüpling, Samuel Lenton, Vito Foderà, Arnout P. Kalverda, Theodoros K. Karamanos

“…Abstract J-domain proteins ( JDPs) act as major regulators of the proteostasis network by driving the specificity of the Hsp70 machine. Their important functions are mediated by a low-complexity glycine-/phenylalanine-rich region (GF-linker) that links the folded J-domain with the substrate binding domain. …”
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Unraveling the neural dynamics of mathematical interference in english reading: A novel approach with deep learning and fNIRS data by Zhijie Liang, Ling Wang, Jianyu Su, Bo Sun, Daifa Wang, Juan Yang

“…To bridge this gap, the present study employs functional near-infrared spectroscopy (fNIRS) to construct a novel dataset on mathematical interference in English acquisition. …”
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Translating proof-of-concept for platelet slip into improved antithrombotic therapeutic regimens by Scott J. Denardo, Pavlos P. Vlachos, Brett A. Meyers, Reza Babakhani-Galangashi, Lin Wang, Zejin Gao, James E. Tcheng

“…Platelet slip extends the observed biological “slip-bonds” to the boundary of functional gliding without contact. As a result, there is diminished engagement of the coagulation cascade by platelets at these surfaces. …”
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EnSLDe: an enhanced short-range and long-range dependent system for brain tumor classification by Wenna Chen, Junqiang Liu, Xinghua Tan, Jincan Zhang, Ganqin Du, Qizhi Fu, Hongwei Jiang

“…IntroductionBrain tumors pose significant harm to the functionality of the human nervous system. There are lots of models which can classify brain tumor type. …”
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Spatiotemporal Urban Evolution Along the China–Laos Railway in Laos Determined Using Multiple Sources of Remote-Sensed Landscape Indicators and Interpretable Machine Learning by Dongxue Li, Jin Tang, Qiao Hu, Mingjuan Dong, Soukanh Chithpanya

“…Constructing high-speed railways (HSRs) is critical for developing countries to stimulate economic growth and urbanization. …”
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Engineering high-density microcrystalline boundary with V-doped RuO2 for high-performance oxygen evolution in acid by Han Wu, Zhanzhao Fu, Jiangwei Chang, Zhiang Hu, Jian Li, Siyang Wang, Jingkun Yu, Xue Yong, Geoffrey I. N. Waterhouse, Zhiyong Tang, Junbiao Chang, Siyu Lu

“…Abstract Designing efficient acidic oxygen evolution catalysts for proton exchange membrane water electrolyzers is challenging due to a trade-off between activity and stability. In this work, we construct high-density microcrystalline grain boundaries (GBs) with V-dopant in RuO2 matrix (GB-V-RuO2). …”
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A high-quality chromosome-level genome assembly of the traditional Chinese medicinal herb Zanthoxylum nitidum by Yanxia Zhu, Guiyu Tan, Qingsong Dong, Baoyou Huang, Yude Peng, Jianping Jiang

“…Herein, we combined PacBio HiFi data together with Hi-C mapping technology to construct a chromosome-scale reference genome assembly for Z. nitidum. …”
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Genetic basis of Fusarium ear rot resistance and productivity traits in a heterozygous multi-parent recombinant inbred intercross (RIX) maize population by Shree Prasad Neupane, Lorenzo Stagnati, Matteo Dell’Acqua, Matteo Busconi, Alessandra Lanubile, Mario Enrico Pè, Leonardo Caproni, Adriano Marocco

“…In this region, we could identify candidates based on their predicted functions and potential roles in plant-pathogen interactions and/or resistance mechanisms. …”
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Transcriptome sequencing reveals the expression profiles of lncRNAs and mRNAs in goat skin tissues with different types of wool coats by Peng Zhao, Hongyu Guo, Jieru Han, Zhiwu Wang, Yanrong Xue, Li Zhang

“…Our findings revealed 130 differentially expressed (DE) lncRNAs and 341 DE mRNAs. GO functional enrichment analysis uncovered some crucial terms such as keratin filament, intermediate filament, cytokine activity, and cytokine receptor binding, along with two pivotal DE lncRNAs: TCONS_00050130 and TCONS_00050142. …”
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Visual Graphical Interpreted Language for Discrete Modeling DLAA by Dmitry Gapanovich, Vladimir Sukhomlin

“…Further, the article considers the expansion of the constructs of language DLAA by introducing semantic functions into them, called activities, following the SysML language. …”
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Entropy Engineering Activates Cu‐Fe Inertia Center From Prussian Blue Analogs With Micro‐Strains for Oxygen Electrocatalysis in Zn‐Air Batteries by Han Man, Guanyu Chen, Fengmei Wang, Jiafeng Ruan, Yihao Liu, Yang Liu, Fang Fang, Renchao Che

“…Through the introduction of the micro‐strains driven by entropy engineering, density functional theory (DFT) calculations and geometric phase analysis (GPA) using Lorentz electron microscopy further elucidate the optimization of the adsorption/desorption of intermediates. …”
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Comprehensive analysis of the critical role of the epithelial mesenchymal transition subtype - TAGLN-positive fibroblasts in colorectal cancer progression and immunosuppression by Junli Zhang, Xinxin Jin, Yachao Hou, Biao Gu, Hongwei Li, Li Yi, Wenjuan Wu, Shangshang Hu

“…An EMT-TME risk model constructed using TAGLN⁺Fib exhibited robust predictive power for CRC prognosis and immunotherapy response. …”
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Non-intrusive load identification method based on VMD and PSO-SVM by YANG Rui, ZOU Xiaosong, XIONG Wei, YUAN Xufeng, ZHENG Huajun, LIU Bin

“…The total load power signal is decomposed using VMD to obtain multiple intrinsic mode functions (IMF), and then, the IMF is reconstructed based on the cliff criterion and singular value decomposition to virtualize single-channel blind source separation into multi-channel blind source separation into fast independent component analysis (FastICA) for load signal separation. …”
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Comparative Analysis of Glycogene Expression in Different Mouse Tissues Using RNA-Seq Data by Ahmad Firoz, Adeel Malik, Sanjay Kumar Singh, Vivekanand Jha, Amjad Ali

“…These DEGGs were then used to construct three interaction networks by using GeneMANIA, from which we detected potential hub genes such as PEMT and HPXN (BvL579), IGF2 and NID2 (BvM501), and STAT6 and FLT1 (LvM442), having the highest degree. …”
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Utilizing Microbial Electrochemical Methods to Enhance Lycopene Production in <i>Rhodopseudomonas palustris</i> by Ningxin Huang, Zhengxiao Wang, Xiao Xiao, Te’er Gai, Dongyue Zhao, Lu Liu, Wei Wu

“…Utilizing <i>Rhodopseudomonas palustris</i> (<i>R. pal</i>), this study constructed a dual-chamber microbial electrosynthesis system, based on microbial electrolysis cells, that was capable of producing lycopene. …”
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Molecular analysis highlights TREM2 as a discriminating biomarker for patients suffering from pancreatic ductal adenocarcinoma by Dimitrios Papakonstantinou, Haiding Wang, Mohamed-Amine Bani, Kevin Mulder, Garett Dunsmore, Alice Boilève, Gérôme Jules-Clément, Leonardo Panunzi, Leslie Robert de Sousa, Carlos de la Calle Fabregat, Marc Deloger, Nicolas Signolle, Grégoire Gessain, Sergey I Nikolaev, Michel Ducreux, Antoine Hollebecque, Florent Ginhoux, Camille Blériot

“…We took advantage of published datasets to construct comprehensive atlases of cells present in primary and metastatic pancreatic cancers. …”
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The Fusion Gene <i>BPI-LY</i>, Encoding Human Bactericidal/Permeability-Increasing Protein Core Fragments and Lysozyme, Enhanced the Resistance of Transgenic Tomato Plants to Bacte... by Lei Ni, Yue Zhang, Yafei Qin, Mei Wang, Daodao Tang, Liantian Chen, Xing Ding, Yilin Zheng, Yu Pan, Jinhua Li, Xingguo Zhang

“…Developing effective resistance against this pathogen remains a major challenge in plant disease management. In this study, we constructed a fusion gene <i>BPI-LY</i> by combining the gene encoding the lipophilic functional domains of human bactericidal/permeability-increasing protein (BPI) with the gene of human lysozyme (LY). …”
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Disulfidptosis ‒ related lncRNAs are biomarkers of prognosis and immune response in Head and Neck Squamous Cell Carcinoma by Ruilin Wang, Qi Zhang, Yuxiu Ma, Xuelin Liu, Tian Lan, Hongling Li

“…DRlncRNAs were identified through Pearson correlation analysis, and a prognostic model consisting of six DRlncRNAs was constructed using Least Absolute Shrinkage and Selection Operator (LASSO) regression, along with univariate and multivariate Cox analyses. …”
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Fracture Behavior of a 2D Imine‐Based Polymer by Bowen Zhang, Xiaohui Liu, David Bodesheim, Wei Li, André Clausner, Jinxin Liu, Birgit Jost, Arezoo Dianat, Renhao Dong, Xinliang Feng, Gianaurelio Cuniberti, Zhongquan Liao, Ehrenfried Zschech

“…A preferred cleavage orientation in transgranular fracture is attributed to the difference in directional flexibility along distinct orientations, which is substantiated by density functional‐based tight binding (DFTB) calculations. …”
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