Stability Assessment of Ground Surface along Tunnels in Karst Terrain Using Improved Fuzzy Comprehensive Evaluation by Kai Zhang, Zelin Zhou, Shougen Chen

“…The ridge-shaped membership functions were constructed to calculate the membership degree for the evaluation indices. …”
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Categorical Frailty Phenotype and Continuous Frailty Index: A Conceptual Overview of Frailty and Its Components among Older Persons in India by Ankit Anand, T.S. Syamala, Md Illias Kanchan Sk

“…Two frailty model was constructed. Education and wealth quintile was used as socio economic indicators. …”
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Integrative analysis of exosomal ncRNAs and their regulatory networks in liver cancer progression by Farzin Mirzaei-nasab, Ahmad Majd, Yousef Seyedena, Nazanin Hosseinkhan, Najma Farahani, Mehrdad Hashemi

“…Future research should focus on the functional implications of these ncRNAs to further elucidate their roles in HCC and explore their applications in clinical settings.…”
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Uncovering multiscale structure-property correlations via active learning in scanning tunneling microscopy by Ganesh Narasimha, Dejia Kong, Paras Regmi, Rongying Jin, Zheng Gai, Rama Vasudevan, Maxim Ziatdinov

“…Abstract Atomic arrangements and local sub-structures fundamentally influence emergent material functionalities. These structures are conventionally probed using spatially resolved studies and the property correlations are deciphered by a researcher based on sequential explorations, thereby limiting the efficiency and scope. …”
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Synergistic modulation of valence state and oxygen vacancy induced by surface reconstruction of the CeO2/CuO catalyst toward enhanced electrochemical CO2 reduction by Fangfang Chang, Zhenmao Zhang, Yan Zhang, Yongpeng Liu, Lin Yang, Xiaolei Wang, Zhengyu Bai, Qing Zhang

“…Herein, we propose the strategy of surface reconstruction and interface integration engineering to construct tuneable Cu0–Cu+–Cu2+ sites and oxygen vacancy oxide derived from CeO2/CuO nanosheets (OD‐CeO2/CuO NSs) heterojunction catalysts and promote the activity and selectivity of CO2RR. …”
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Photopharmacology reveals high-specificity linkage of Ca2+ entry at TRPC6 nanodomains to NFAT activation in mast cells by Denis Krivić, Olga Panasiuk, Johannes Pilic, Roland Malli, Roland Malli, Bernadett Bacsa, Bernadett Bacsa, Sanja Ćurčić, Sanja Ćurčić, Klaus Groschner, Klaus Groschner

“…IntroductionPhotopharmacology has recently emerged as a strategy for high-precision modulation of immune functions. Here we explored efficiency and specificity of interventions based on light-induced TRPC6 activation in the RBL-2H3 mast cell model.ResultsExpression of TRPC6 fusion constructs in RBL-2H3 allowed for generation of temporally well-defined, cytosolic Ca2+ transients in response to photoisomerization of the TRPC6 actuator OptoBI-1. …”
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Molecular origin of asymmetric yield surface of crosslinked epoxy polymers by Jinyoung Kim, Kyeongmin Hong, Yong-Seok Choi, Dayoung Jang, Jang-Woo Han, Hyungbum Park

“…In this study, we investigate the multiaxial mechanical behavior of thermosetting epoxy polymers and explore the asymmetry between tension and compression in their yield surfaces at the molecular level using molecular dynamics simulations, complemented by experimental validation through polymer synthesis. After constructing an atomistic-scale amorphous epoxy system based on molecular dynamics simulations, we derived equivalent stress–strain curves and yield surfaces as functions of the degree of crosslinking through biaxial deformation analysis. …”
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An mRNA expression atlas for the duck with public RNA-seq datasets by Qiuyu Tao, Anqi Huang, Jingjing Qi, Zhao Yang, Shihao Guo, Yinjuan Lu, Xinxin He, Xu Han, Shuaixue Jiang, Mengru Xu, Yuan Bai, Tao Zhang, Shenqiang Hu, Liang Li, Lili Bai, HeHe Liu

“…A thorough understanding of the functional genomic and transcriptomic sequences is crucial for improving production efficiency. …”
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Tradeoffs When Building and Running Cohort and Patient-Level Markov Simulation Models by Balázs Nagy, Ahmad Nader Fasseeh, Jonathan D. Campbell, Zoltán Kaló, Kareem Ahmed El-Fass, Rok Hren, Bertalan Németh

“…Both the CH and PL models were constructed using identical datasets and similar assumptions. …”
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Identification of exosome-related genes in NSCLC via integrated bioinformatics and machine learning analysis by Zhenjie Sun, Tianyu Du, Guosheng Yang, Yinghuan Sun, Xuyang Xiao

“…The present study identified 59 exosome-associated differentially expressed genes (EA-DEGs) from the Gene Expression Omnibus (GEO) and GeneCards databases. Functional analysis indicated the involvement of the EA-DEGs in NSCLC-related pathways, including the cell cycle, DNA replication, and the immune response. …”
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Randomized clinical trial on the effects of early cognitive interventions for children with acquired brain injury by Claudia Corti, Susanna Frigerio, Monica Recla, Susanna Galbiati, Valentina Pastore, Chiara Porro, Fabio Storm, Cosimo Urgesi, Sandra Strazzer

“…Visual sustained attention and other cognitive measures of attention, memory, visual-spatial/visual-constructional abilities and executive functions were primary and secondary outcomes, respectively. …”
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Effect of solid solution rare earth (La, Ce, Y) on the mechanical properties of α-Fe by Bai Chunying, Bai Guojun, Liu Xiangjun, Wang Ting

“…In this article, the Fe-RE (La, Ce, Y) systems were constructed based on the density functional theory, and mechanical properties of doping systems were calculated. …”
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Nerve growth factor-loaded biomimetic prussian blue nanocomplexes for reversing osteoporosis via promoting osteoblast precursor cell proliferation and differentiation by Yuyi Tian, Yihan Lin, Hao Liu, Xiaona He, Shang Zhu, Luhong Dai, Yuqi Lu, Lihong Liu, Bin Liu

“…In this study, Prussian blue nanoparticles (PB NPs) were initially functionalized with a polydopamine (PDA) coating. Nerve growth factor (NGF) was subsequently immobilized on the PDA layer, followed by the hybrid membrane coating composed of red blood cell membrane (RBCm) and MC3T3-E1 cell membrane (MC3T3m), thereby constructing a biomimetic Prussian blue nanocomplex loaded with NGF (MPDN NPs). …”
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Semantic Modeling for SNPs Associated with Ethnic Disparities in HapMap Samples by HyoYoung Kim, Won Gi Yoo, Junhyung Park, Heebal Kim, Byeong-Chul Kang

“…To analyze the biologically functional implications for ethnicity-specific SNPs, we focused on constructing a semantic network model. …”
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The Vulpes vulpes montana genome provides insights into high-altitude adaptation mechanisms of the Vulpes species by Tianshu Lyu, Zhao Liu, Tian Xia, Shengyang Zhou, Jiaohui Fang, Kaijia Dong, Lidong Wang, Lupeng Shi, Yuehuan Dong, Zihao Sheng, Xiaoyang Wu, Xiufeng Yang, Honghai Zhang

“…A total of 20,056 protein-coding genes were predicted in the assembled genome, 93.06% of which were functionally annotated. Comparative genomics analysis reveals unique and shared HA adaptation mechanisms in HA Vulpes species. …”
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Deep generative model for the inverse design of Van der Waals heterostructures by Shikun Gao, Qinyuan Huang, Chen Huang, Cheng Li, Kaihao Liu, Baisheng Sa, Yadong Yu, Dezhen Xue, Zhe Liu, Mengyan Dai

“…Experiments demonstrate that ConditionCDVAE+ achieves optimal root mean square error for crystal reconstruction, with improved generation quality. Density Functional Theory calculations confirms 99.51% of generated samples converge to energy minima, indicating superior ground-state convergence. …”
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Need-based remote exercise management platform for colorectal cancer patients with intestinal stoma: design and pilot usability evaluation by Cui Yao, Cui Yao, Lingyu Ding, Lingyu Ding, Jing Yang, Jing Yang, Yueming Sun, Yueming Sun

“…Based on these comprehensive needs assessments, we constructed a specialized remote exercise management platform. …”
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Identification of stemness subtypes and prognostic modeling in thyroid cancer: the critical role of DPYSL3 in tumor progression and immune microenvironment by Jialong Yu, Wei Luo, Guangwei Xu, Mei Tao, Yuqi Wang, Qiman Dong, Linfei Hu, Xiukun Hou, Jingzhu Zhao, Dapeng Li, Songfeng Wei, Xianhui Ruan, Xiangqian Zheng

“…Through the application of four machine learning algorithms and LASSO regression, we identified key genes and constructed a prognostic model based on the stemness signature. …”
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A study on collaborative governance of excessive medical care based on three-way evolutionary game and simulation by Hanxiang Gong, Hanxiang Gong, Tao Zhang, Xi Wang, Baoling Wu, Shufang Zhao

“…Improving collaborative governance for overtreatment requires establishing comprehensive laws and regulations, leveraging government regulatory functions, strengthening internal constraint mechanisms in healthcare institutions, and raising patients' awareness of their rights and supervisory responsibilities.…”
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Soliton solutions to generalized (3 + 1)-dimensional shallow water-like equation using the (ϕ'/ϕ,1/ϕ)-expansion method by Pinakee Dey, Lamiaa H. Sadek, M. M. Tharwat, Shuvo Sarker, Rezaul Karim, M. Ali Akbar, Nasser S. Elazab, M. S. Osman

“…With this approach, we produce new propagating wave solutions for this model in the form of hyperbolic, trigonometric, and rational functions. In addition, we offer two- and three-dimensional graphical representations to help visualize the intricate physical phenomena of the system. …”
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