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12721
The impact of interactions between heavy metals and smoking exposures on the formation of oral microbial communities
Published 2024-12-01“…By comparing the oral bacterial communities and functional pathways between the four groups, we found significant differences in bacterial communities and functional pathways between the groups. …”
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12722
Modelling soil prokaryotic traits across environments with the trait sequence database ampliconTraits and the R package MicEnvMod
Published 2024-11-01“…Overall, our approach enables robust inference of ecologically interpretable traits combined with environmental modelling allowing to harness traits as bioindicators of soil ecosystem functioning.…”
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12723
The role of hypoxia-senescence co-related molecular subtypes and prognostic characteristics in hepatocellular carcinoma
Published 2025-04-01“…The expression pattern and functional characteristics of MLH1 gene in HCC were verified. …”
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12724
Dysfunction of PDE4DIP contributes to LVNC development by regulating cell polarity, skeleton, and energy metabolism via Rho-ROCK pathway
Published 2025-09-01“…Overexpression and knockdown of PDE4DIP were constructed in H9C2 cells and neonatal Sprague–Dawley rat primary cardiomyocytes, respectively. …”
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12725
Screening, Genome Sequencing and Tolerance Mechanism Analysis of Bile Acid-resistant Pediococcus pentosaceus 32M07
Published 2025-09-01“…The 16S rRNA gene and the core genome phylogenetic tree results were consistent, confirming that strain 32M07 was taxonomically classified as Pediococcus pentosaceus. Based on functional annotations and metabolic relationships of bile acid metabolism and transport-related genes in databases including COG, GO, and KEGG, a bile acid metabolic model for Pediococcus pentosaceus 32M07 was constructed. …”
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12726
Comparative transcriptomes reveal insights into different host responses associated with Fusarium head blight resistance in wheat
Published 2025-04-01“…These results will provide new insights into further dissecting of the functional genes and lncRNAs involved in wheat FHB resistance.…”
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12727
GG-NER’s role in androgen receptor signaling inhibitor response for advanced prostate cancer
Published 2024-12-01“…Additionally, we mapped tumor mutations to delineate the mutational landscapes across different risk groups and explored functional pathways through GO, KEGG, and GSEA analyses. …”
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12728
Aquaponics model can provide better productivity: Microorganisms affect the growth and health of tilapia
Published 2025-03-01“…The relationships between fish immunological and digestive functions, water quality, and bacterial populations were not well understood. …”
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12729
Bioinformatics and Network Pharmacology Identify the Therapeutic Role of Guominkang in Allergic Asthma by Inhibiting PI3K/Akt Signaling
Published 2025-02-01“…The aim of this study was to explored the mechanism of action through which GMK combats AA.Methods: Potential target genes for the compounds were identified from the database and subjected to functional enrichment analysis. Subsequently, a protein-protein interaction (PPI) network was constructed in order to screen the core target and confirmed by molecular docking. …”
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12730
Transcriptome-wide analysis reveals potential roles of CFD and ANGPTL4 in fibroblasts regulating B cell lineage for extracellular matrix-driven clustering and novel avenues for imm...
Published 2025-05-01“…However, the compositional patterns of ECM in breast cancer and their underlying biological functions remain elusive. Methods Transcriptome and genome data of breast cancer patients from TCGA database was downloaded. …”
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12731
Characterization of lactylation modification subtypes and the promoting role of CCL20 in hepatocellular carcinoma progression
Published 2025-07-01“…A lactylation modification-related prognostic model was subsequently constructed using LASSO-Cox and multivariate Cox regression analyses. …”
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12732
The Aporia of Reality/Imagination: Uncertainty in Selected Iranian Monodramas and Surrealist Dramas
Published 2025-06-01“…This research explores how the aporia of reality and imagination functions as a rhetorical tool that renders drama as self-deconstructive. …”
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12733
Identification and evaluation of biomarkers for diagnosis of chronic hepatitis B using RNA-seq
Published 2025-08-01“…A machine learning model was constructed to diagnose CHB by combining three identified biomarkers. …”
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12734
Investigating Digital Storytelling as a Tool of Improving/ Developing Information Literacy Skills
Published 2024-11-01“…Digital storytelling emphasizes the group process and people's experience in sharing stories, visual and verbal functions that are necessary for understanding language and thinking from the perspective of cognitive neuroscience. …”
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12735
Time-Course Renal and Pulmonary Injury Analysis and Bioinformatics Screening of Core Pathogenic Genes and Immune Cell Infiltration Patterns in a Sepsis
Published 2025-08-01“…A sepsis risk model constructed using five key genes—CD8A, ITGAM, CXCL8, CCL5, and LCK—demonstrated high predictive accuracy. …”
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12736
The interlinked trajectories of interpersonal attachment and maladaptive behaviors among Chinese adolescents—a latent growth modeling approach
Published 2025-07-01“…Specifically, latent growth curve modeling was conducted to estimate the trajectories of the seven key constructs, with Wald tests assessing differences in growth factors across constructs. …”
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12737
Microbial diversity in active and abandoned desert kangaroo rat burrows and from proximal surface sand
Published 2025-05-01“…ABSTRACT Desert kangaroo rats (Dipodomys deserti) construct burrows that can create micro-niches favorable to increased microbial activity. …”
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12738
Exploring the causal relationship between hemoglobin and pancreatic cancer and its potential mechanisms through bioinformatics and Mendelian randomization
Published 2025-08-01“…Transcriptomic datasets from TCGA and GEO were then integrated to identify differentially expressed genes, followed by functional enrichment analysis. LASSO regression was subsequently applied to select characteristic genes and construct a prognostic model, which was then subjected to validation. …”
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12739
Sufficient conditions for convergence of positive solutions to linearized two-dimensional sediment transport problem
Published 2017-03-01“…The linear difference schemes are constructed and studied; model and some practically important tasks are solved. …”
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12740
PLIN2 promotes colorectal cancer progression through CD36-mediated epithelial-mesenchymal transition
Published 2025-07-01“…The prognostic model was constructed by univariate survival analysis and LASSO regression analysis. …”
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