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12701
Climate change distress and impairment in Germany
Published 2024-09-01“…It is important, however, to differentiate between the affective experience of distress over climate change and the functional impairments associated with climate change. …”
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12702
Creation of an innovative diagnostic framework for hepatocellular carcinoma employing bioinformatics techniques focused on senescence-related and pyroptosis-related genes
Published 2025-02-01“…Additionally, real-time fluorescence quantitative PCR confirmed that genes ANXA2, APOA1, EZH2, IGF2BP3, SQSTM1, and TNFRSF11B were significantly overexpressed in the peripheral blood of patients with LIHC in comparison to normal volunteers, thereby validating the prognostic risk model’s accuracy.ConclusionsThis study systematically elucidated the functions of genes associated with senescence and pyroptosis in LIHC cells. …”
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12703
DYNAMICS OF CHANGES IN THE ELECTROMYOGRAPHIC INDICATORS OF MASTICATING MUSCLES DURING THE PROSTHETIC REHABILITATION OF PATIENTS WITH PATHOLOGICAL ABRASION OF TEETH WHEN USING REMOV...
Published 2022-12-01“… Pathological abrasion of teeth is a fast process, accompanied by changes in the dental tissues and tissues of periodontium, as well as a disorder of the functions of the masticatory muscles and TMJ (temporomandibular joint). …”
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12704
INDIAN MYTHS AS THE BASIS OF HART CRANE’S MYTHMAKING
Published 2023-12-01“…The purpose of the research is to identify and analyze the ancient mythologies used by Hart Crane to construct the future of America, which will be inspired by the new myth. …”
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12705
Analysis dynamic characteristics brushless motor of the mechatronic system in conditions of parametric uncertaintyby computer simulation methods
Published 2022-06-01“…A vector-matrix block diagram for calculating the sensitivity functions of a brushless motor is formed, the characteristic feature of which is the presence of a non-zero matrix of free terms, reduced to the input of the sensitivity model. …”
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12706
DEVELOPMENT OF A MODEL FOR THE DYNAMICS OF PROBABILITIES OF STATES OF SEMI-MARKOV SYSTEMS
Published 2021-09-01“…This technique significantly increases the adequacy of the resulting mathematical models of the functioning of the system, since it allows one to move away from overly obligatory exponential descriptions of the original distribution laws. …”
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12707
MSC1 Cells Suppress Colorectal Cancer Cell Growth via Metabolic Reprogramming, Laminin–Integrin Adhesion Signaling, Oxidative Stress Resistance, and a Tumor-Suppressive Secretome
Published 2025-06-01“…Functional and transcriptional enrichment analyses pinpointed key mechanisms. …”
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12708
The potential mechanism of MicroRNA involvement in the regulation of muscle development in weaned piglets by tryptophan and its metabolites
Published 2025-04-01“…Furthermore, we constructed a protein-protein interaction (PPI) network for the target genes, with the enriched core gene cluster functions associated with cellular proliferation, signaling pathways, hormone release, and muscle development. …”
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12709
The relationship between physical activity and Internet addiction among Chinese adolescents: exploring latent profile analysis and multi-level mediating mechanisms
Published 2025-07-01“…The measurement model supported adequate construct validity and internal consistency across all latent variables, ensuring the reliability of subsequent structural analyses. …”
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12710
Optimal dosage of group-based organized physical activity for enhancing social abilities in autistic children: insights from a multilevel meta-analysis
Published 2025-07-01“…The meta-analysis results clearly show that GBOPA can significantly improve social abilities (g = 0.48, Q = 114.84), including social functioning (g = 0.50, Q = 62.97) and communication (g = 0.37, Q = 48.07), in autistic children. …”
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12711
Metabolic profiling of glioblastoma and identification of G0S2 as a metabolic target
Published 2025-05-01“…The predictive model showed robust performance in forecasting the survival of glioma patients. Functional analysis identified G0S2 as a key metabolic regulator highly expressed in gliomas. …”
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12712
Biogeographic patterns and adaptive strategies of microbial carbon metabolic profiles in paddy soils in the Chinese Mollisol region
Published 2025-04-01“…Compared with HCS, LCS presented higher abundances of C cycling pathways involving aerobic respiration, C fixation, and methanogenesis pathways, as well as higher levels of carbohydrate esterase (CE) and glycosyl transferase (GT) classes. 211 metagenome-assembled genomes (MAGs) with diverse C metabolic functions were constructed. Among these, high-quality MAG292, assigned to the Nanopelagicales order, had a significantly positive correlation with TC and was more abundant in HCS. …”
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12713
Cognition and behavior in adults with neurofibromatosis type 1
Published 2024-11-01“…As NF1 is incurable and presents with a wide range of physical and mental symptoms, knowledge of neurocognitive and behavioral functioning can be an important aid in understanding their functional impact, and developing treatment options. …”
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12714
WTAP/YTHDF1-mediated m6A modification amplifies IFN-γ-induced immunosuppressive properties of human MSCs
Published 2025-05-01“…RIP-qPCR, western blot, qRT-PCR and RNA stability assays were used to determine the regulation of WTAP/m6A/YTHDF1 signaling axis in the expression of immunosuppressive molecules. Further, functional capacity of T cells was tested using flow cytometry, and both DSS-induced colitis mice and CIA mice were constructed to clarify the effect of WTAP and YTHDF1 in MSC-mediated immunosuppression. …”
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12715
Microbiome and fragmentation pattern of blood cell-free DNA and fecal metagenome enhance colorectal cancer micro-dysbiosis and diagnosis analysis: a proof-of-concept study
Published 2025-05-01“…Based on the differential microbes and functions, random forest (RF) models are constructed for adenoma and CRC diagnosis. …”
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12716
Exploring fecal microbiota signatures associated with immune response and antibiotic impact in NSCLC: insights from metagenomic and machine learning approaches
Published 2025-07-01“…Antibiotic exposure significantly influenced the abundance and functional potential of these key taxa. KEGG-based functional analysis revealed the enrichment of amino acid metabolism pathways in responders. …”
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12717
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12718
Optimized design of B-B surface through Bézier geodesic trilateral(过Bézier测地三边形的B-B曲面优化设计)
Published 2025-01-01“…Firstly, the boundary geodesic interpolation condition is used to determine the two rows of control points of the surface boundary line and adjacent boundary line; Secondly, two methods of minimizing surface Bending energy functional and Dirichlet energy functional are given to optimize the remaining control points of the surface. …”
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12719
Single-cell atlas of human gingiva unveils a NETs-related neutrophil subpopulation regulating periodontal immunity
Published 2025-06-01“…Despite the critical role of NETs in the development and progression of periodontitis, their specific functions and mechanisms remain unclear. Objectives: To demonstrate the important functions and specific mechanisms of NETs involved in periodontal immunopathology. …”
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12720
Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage
Published 2025-02-01“…Additionally, we discovered 19 DEMs associated with CVS and integrated them with mRNA dataset analysis to construct a miRNA-mRNA network, which comprised 8 functionally differentially expressed DEMs and 6 target mRNAs. …”
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