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12661
Research progress and implications of the application of large language model in shared decision-making in China’s healthcare field
Published 2025-07-01“…Large Language Models (LLMs), with their powerful natural language processing capabilities, demonstrate unique advantages in enhancing communication efficiency, supporting personalized decision-making, and promoting multi-party collaboration. Key functionalities such as information integration, personalized support tools, and sentiment analysis significantly improve patient engagement and decision quality. …”
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12662
Molecular dynamics and machine learning unlock possibilities in beauty design—A perspective
Published 2025-01-01“…In the small data regime, physics-based approaches model the interaction between the molecule being designed and proteins of key physiological functions, providing structural insights into the mechanism. …”
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12663
Precision nanoparticles for drug delivery, cell therapy tracking, and theranostics
Published 2024-11-01“…Unique constructions have thus opened up original and innovative possibilities in biotechnological and biomedical fields such as imaging, biosensors, rapid diagnostics, drug delivery, medical implants, and tissue engineering. …”
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12664
A health management system for large vertical mill
Published 2020-03-01“…Finally, the health management system, including the functions of condition monitoring, fault diagnosis, and trend prediction for large vertical mill is implemented using Microsoft Visual Studio C # and Microsoft SQL Server.…”
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12665
First synthesis of the LaZnO3 biochar perovskite used as a photocatalyst with the enhanced deactivation mechenism and regenerable performance
Published 2025-07-01“…Abstract This study innovatively modified LaZnO3 perovskite with waste spirulina biochar to construct a new photocatalyst system, LaZnO3-Biochar (LaZnO3-B). …”
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12666
Tailoring Dynamic Synaptic Plasticity in FeTFT Optoelectronic Synapse for Associative Learning
Published 2025-05-01“…Furthermore, a 3 × 3 FeTFT array is constructed to demonstrate its potential applications in memory functions. …”
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12667
Three-Dimensional Printed Biomimetic Elastomeric Scaffolds: Experimental Study of Surface Roughness and Pore Generation
Published 2025-02-01“…Tissue engineering is an emerging field within biomedicine, related to developing functional substitutes for damaged tissues or organs. …”
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12668
Coupling Enteromorpha prolifera-derived N-doped biochar with Cu-Mo2C clusters for selective CO2 hydrogenation to CO
Published 2025-02-01“…Herein, an efficient RWGS catalyst is constructed through Enteromorpha prolifera–derived N-rich mesoporous biochar (EPBC) supported atomic-level Cu-Mo2C clusters (Cu-Mo2C/EPBC). …”
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12669
Identification of a PANoptosis-related long noncoding rna risk signature for prognosis and immunology in colon adenocarcinoma
Published 2025-04-01“…Distinct responses to various antitumour drugs were observed between the two risk groups. Additionally, we constructed a ceRNA network based on PRlncRNAs, and GO enrichment analysis of the predicted mRNAs revealed different functions. …”
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12670
Quand l’écriture entre dans le quotidien : les mots de la mémoire dans les livres de raison (Provence, fin xve-xviiie siècles)
Published 2025-05-01“…This corpus, already transcribed in full in Word format, will then enable us to apprehend the common lexicon of memory (avoir bonne mémoire, se ressouvenir, enregistrer, marquer affin de cognoistre par le temps, tesmoigner etc.), particularly in the titles attributed to these registers by the scribes (Livre de Memoyres, cervant de memoire, Memoires mes affaires, Memoires du tempts, Memorial, Record et memoyre etc.), while the editorial and literary genre of the Mémoires was simultaneously being constructed. This lexicon is correlated with the functions of memory aids and records (these books of reason could be used as evidence in court), which allows us to question the way words and signs functioned in memory techniques (repetitions, reformulations, mnemonic use of genealogies, reference to historical events, etc.) developed by scribblers often unfamiliar with the learned “arts of memory”. …”
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12671
Identification of a novel missense variant in the LMX1B gene associated with nail-patella syndrome in a Chinese family
Published 2025-05-01“…Wild-type and mutant LMX1B overexpression plasmids were constructed to investigate the functional consequences of the variant. …”
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12672
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12673
The Significance of Cellular Senescence Hub Genes in the Diagnosis and Subtype Classification of a Comprehensive Database of Gene Expression in Intervertebral Disc Degeneration
Published 2025-03-01“…We then conducted Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses to explore their functions and associated pathways. We identified hub genes by constructing a protein–protein interaction (PPI) network and further validated these genes using clinical samples. …”
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12674
The mechanism of Weiqi decoction treating gastric cancer: a work based on network pharmacology and experimental verification
Published 2025-04-01“…A protein–protein interaction (PPI) network was constructed via the STRING database, and functional enrichment analyses were conducted using the DAVID platform. …”
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12675
Analysis and validation of necroptosis-related diagnostic biomarkers associated with immune infiltration in bronchopulmonary dysplasia
Published 2025-07-01“…We found the primary biological functions and pathways of DE-NRGs, including necroptosis, and regulation of inflammatory response. …”
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12676
RELIABILITY, VALIDITY AND SENSITIVITY OF RUSSIAN VERSIONS OF PEDSQL GENERIC CORE SCALE AND PEDSQL RHEUMATOLOGY MODULE QUESTIONNAIRES
Published 2009-01-01“…Estimation of reliability of questionnaires was held with calculation of Cronbach's alpha, constructive validity – with method of “known groups” with the help of analysis of dependence of quality of life indices from index of functional insufficiency (estimated by CHAQ questionnaire). …”
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12677
Using computational pharmacology and experimental verification to decode mechanism of Qing-Wei-San in treating periodontitis
Published 2025-07-01“…A component-target-target network was constructed using protein-protein interaction data, pathogenic genes, and active components. …”
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12678
Integrating multi-omics to unveil PSMD12 as a critical gene in promoting brain metastases of lung adenocarcinoma
Published 2025-06-01“…Mechanistically, we developed an algorithm to construct an upstream regulator network of PSMD12 overexpression. …”
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12679
Research on screening key proteins related to the pathogenesis of sepsis associated encephalopathy based on DIA proteomics technology
Published 2024-12-01“…The differential proteins between the two patient groups were identified and functionally analyzed using bioinformatics methods. Key differential proteins were further screened using machine learning models such as Extreme Gradient Boosting (XGBoost) and Least Absolute Shrinkage and Selection Operator (LASSO) regression to construct a nomogram and evaluate its diagnostic performance. …”
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12680
Comprehensive analysis of phagocytosis regulatory genes in bladder cancer: implications for prognosis and immunotherapy
Published 2025-06-01“…A prognostic model was constructed and verified, and the risk score was calculated. …”
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