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12521
CircRNA-miRNA-mRNA regulatory network in high-altitude hypobaric hypoxia-induced hearing impairment and hearing acclimatization
Published 2025-03-01“…A circRNA-miRNA-mRNA competing endogenous RNA (ceRNA) network was also constructed. The DEmRNAs in this network were functionally annotated using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses based on Metascape. …”
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12522
Pontos de abastecimento de pulverizadores agrícolas: uma revisão comparando os modelos em uso Agricultural chemical handling pads: a review comparing the models in use
Published 2011-11-01“…Recently there have been advances in the constructive philosophy of sprayers handling pads, with the introduction of residue redressing in situ, through biodegradation which became known as biobeds, amongst others. …”
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12523
Shared pyroptosis pathways and crosstalk genes underpin inflammatory links between periodontitis and atherosclerosis
Published 2025-03-01“…Following batch effect correction and normalization, differential expression analysis was conducted using the limma package in R. Functional enrichment analysis was performed with the clusterProfiler package to identify key pathways, while heatmaps and pathway networks were constructed to visualize the relationships among pyroptosis genes and crosstalk genes. …”
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12524
Identification of the prognostic effect of mitophagy-related genes in acute myeloid leukemia
Published 2025-08-01“…A prognostic risk model was constructed and validated. Functional enrichment, immune infiltration, and drug sensitivity analyses were conducted to explore the biological relevance of the model. …”
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12525
Decellularized porcine liver scaffold for maintaining the viability and capacity of pancreatic islets
Published 2025-03-01“…Bioengineered pancreatic constructs based on scaffolds made from decellularized tissues and pancreatic islets (PIs) may be used to extend the functional activity of transplanted PIs in patients with type I diabetes. …”
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12526
m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy
Published 2025-07-01“…Abstract Background Lung cancer is the most common malignant tumour and the leading cause of cancer-related death. circular RNAs (circRNAs) have important biological functions and are closely related to tumour development. …”
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12527
IL7-IL7R Interaction Mediates Fibroblast-Driven Macrophage-to-Osteoclast Differentiation in Periodontitis
Published 2025-05-01“…Pengjie Huang,1,* Li Gao,1,* Jiezhong Guan,1 Yijiao Li,1 Yibing Jia,1 Zixiang Zeng,1 Yurun Chen,1 Linge Wang,2 Weichang Li,1 Yan Wang,1 Bo Yang1 1Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, People’s Republic of China; 2South China Advanced Institute for Soft Matter Science and Technology, School of Molecular Science and Engineering, Guangdong Provincial Key Laboratory of Functional and Intelligent Hybrid Materials and Devices, South China University of Technology, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yan Wang, Email wangyan9@mail.sysu.edu.cn Bo Yang, Email yangb86@mail.sysu.edu.cnAim: To identify osteoclastogenic macrophage subsets and their regulatory mechanisms in periodontitis.Methods: We integrated single-cell RNA sequencing datasets from human and murine periodontitis to construct a comprehensive macrophage and monocyte atlas. …”
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12528
LIN28B promotes the progression of endometrial cancer through upregulating MYC and correlates with immune microenvironment
Published 2025-07-01“…Functional analyses revealed that LIN28B knockdown markedly suppressed EC cell proliferation, migration, and invasion, concurrent with MYC downregulation. …”
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12529
Development and validation of a machine-learning-based model for identification of genes associated with sepsis-associated acute kidney injury
Published 2025-07-01“…Functional enrichment analysis revealed important associations of AKI with immune responses and cell adhesion processes. …”
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12530
Identification and characterization of salt-tolerance relative miRNAs in Procambarus clarkii by high-throughput sequencing
Published 2019-11-01“…We constructed four sRNA library of P. clarkia from different tissues and treatments by using high-throughput sequencing technology. …”
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12531
Expert-Trajectory-Based Features for Apprenticeship Learning via Inverse Reinforcement Learning for Robotic Manipulation
Published 2024-11-01“…This paper explores the application of Inverse Reinforcement Learning (IRL) in robotics, focusing on inferring reward functions from expert demonstrations of robot arm manipulation tasks. …”
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12532
Trivalent Phospha-Brook rearrangement enabled practical deoxygenative phosphonylation of carbonyls
Published 2025-04-01“…The reaction demonstrates excellent substrate scope, remarkable functional group compatibility, and operational simplicity, offering significantly enhanced atom-economy compared to previous deoxygenative strategies. …”
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12533
Testing a digital and interactive scale (the three circles) to assess emotion regulation
Published 2025-05-01“…Here we report that evaluation indicated the measure had good construct validity with other validated self-report measures of emotion, emotion regulation, and mental health. …”
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12534
Sustainable development of a region based on the assessment of anthropogenic load (through the example of the ecosystems of the Kizilyurt district and the city of Kizilyurt)
Published 2025-04-01“…A principal trend of the modern world is a requirement for sustainable development, which involves taking into account not only socio-economic but also environmental factors, one of which is the anthropogenic load on the ecosystem.Since the anthropogenic load varies across a region in the entire range of values from 0 to 100 %, a strategy for its eco-development should be based on estimates of consumption potentials in distributed parameters so that the total load does not exceed the capacity of the entire territory analysed.All the significance indicators used in the study in various combinations are included as elements of the structural and functional model. The simulation and balance model "Region" constructed as a result of the calculations establishes a direct relationship "impact – response" in ecosystems, which is achieved by indexing the anthropogenic load relative to the capacity of the environment.The results of the calculations obtained of the anthropogenic load can form the basis for solving a number of related challenges. …”
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12535
About the Possible Mechanisms of the Influence of Optical Intraocular Implants on the Characteristics of Neurosensory Rehabilitation and Adaptation in Patients with Pseudophakia. L...
Published 2021-04-01“…Analysis of domestic and foreign literature has demonstrated the absence of a systematic approach to the study of sensorineural adaptation in patients after implantation of monofocal IOLs, which would make it possible to reasonably develop requirements for qualitative and constructive characteristics in the production of intraocular lenses to improve the quantitative and qualitative indicators of their visual functions in order to reduce the terms of rehabilitation and improvement of quality of life indicators in patients with pseudophakia. …”
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12536
Neighbor interaction-based personalised transfer for cross-domain recommendation
Published 2023-12-01“…Moreover, a meta-network based on users' transferable features is trained to construct personalised mapping functions for each user. …”
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12537
Modelling of the Ukrainian labor market: system dynamics approach
Published 2024-11-01“…The purpose of the article is to develop a System Dynamics model of the functioning and development of the Ukrainian labor market, which can subsequently be used to simulate various government decisions and policies. …”
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12538
A Complex Wavelet-Based OTFS Scheme for LEO Satellite Communication
Published 2025-01-01“…This paper presents a mathematical model for the proposed CW-OTFS system constructed using a straightforward matrix multiplication approach. …”
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12539
Geometrical frustration in nonlinear mechanics of screw dislocation
Published 2024-12-01“…The modelling begins with a continuous distribution of dislocation density, which is transformed into torsion [Formula: see text] through the Hodge duality. The plasticity functional is constructed by applying the Helmholtz decomposition to bundle isomorphism, which is equivalent to the Cartan first structure equation for the intermediate configuration [Formula: see text]. …”
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12540
Advances in nanocarrier technology for drug encapsulation: a comprehensive overview
Published 2025-07-01“…The final bibliometric dataset was then constructed using 42 papers spanning 2013– 2024 including recent developments. …”
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