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12421
Recognition of State of Health Based on Discharge Curve of Battery by Signal Temporal Logic
Published 2025-02-01“…Among the different objective functions, the highest mean accuracy of the STL reaches 87.5%. …”
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12422
Key gene screening and diagnostic model establishment for acute type a aortic dissection
Published 2025-04-01“…Functional enrichment revealed associations with immune cell migration, vascular development regulation, extracellular matrix pathways, and the PI3K-Akt signaling pathway. …”
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12423
Identification of anoikis-related genes in heart failure: bioinformatics and experimental validation
Published 2025-08-01“…GEO2R was used to screen for differentially expressed genes (DEGs), then by overlapping DEGs with ARGs, differentially expressed ARGs (DEARGs) were screened. The biological functions of the DEARGs were determined using DAVID. …”
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12424
Application of multilayer network in protein-protein interaction networks (PPI) of rice and cancer
Published 2017-01-01“…We divided the rice cell into several organelles to study the relationship between organelles and cell functions. Moreover, we used different cancer tissues and normal tissues in human body to construct two multilayer PPI and study the underlying mechanics of cancer comparing with the normal tissues.We introduced the mathematical theories of multilayer networks along with the concept of mult-idegree, overlap of edge, activity of node, multiplexity, degree correlation, participation coefficient and degree correlation coefficient, which are used to analyze the nontrivial structure and properties in PPIs of rice, cancer and normal tissue.In rice PPIs, we investigated the power-law distribution of edge overlap and node activity, and found important proteins related to functional organelles in cell by analyzing participation coefficient, and organelles of strong correlations or weak correlations by analyzing heat map of layer’s degree. …”
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12425
Evaluation of 3D Nonlinear Earthquake Behaviour of the Ilısu CFR Dam under Far-Fault Ground Motions
Published 2019-01-01“…In the recent times, many huge concrete face rockfill dams (CFRDs) have been modelled and constructed in the world, and many of these dams are located on the strong earthquake zones. …”
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12426
Validation of the uncertainty stress scale-high-risk pregnancy - Chinese brief version: Rasch analysis
Published 2025-01-01“…Confirmatory factor analysis (CFA) and Rasch model to examine the construct validity of the short version of the USS-HRPV-C. …”
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12427
Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout
Published 2025-06-01“…This study aimed to identify key genes and elucidate regulatory mechanisms underlying gout development through bioinformatics analysis combined with experimental validation.MethodsTranscriptome dataset GSE160170 and single-cell dataset GSE211783 were analyzed using differential expression analysis and weighted gene co-expression network analysis (WGCNA). Functional enrichment, protein-protein interaction (PPI), ceRNA, and transcription factor networks were constructed. …”
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12428
Reference-guided detection of the transcriptome reveals circular RNA-related competing endogenous RNA networks in response to three respiration pathogens in pig lungs
Published 2025-06-01“…Most differentially expressed circRNAs were up- and down-regulated in response to specific pathogens among PRRSV, ASFV, and Mhp. The functional annotation showed that ceRNA networks of the circRNAs that were specifically up-regulated in response to Mhp and ASFV were significantly enriched in humoral immunity-related functions and reactive oxygen species-related signal pathways, respectively. …”
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12429
Transient Expression of Recombinant Antimicrobial Peptide Meucin18 in Nicotiana tabacum and its Antimicrobial Susceptibility Testing
Published 2025-03-01“…Gateway LR cloning was performed to produce expression construct pEAQ-HT-DEST3-Meucin18. A quantity of 100 ng expression construct was transformed into electrocompetent Agrobacterium tumefaciens GV3101 through electroporation, pulsed at 1800V for 5 ms. …”
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12430
Mechanisms and network pharmacological analysis of Yangyin Fuzheng Jiedu prescription in the treatment of hepatocellular carcinoma
Published 2023-02-01“…The gene–gene inner and component‐target‐pathway networks were constructed and analyzed to screen the key targets. …”
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12431
Prognostic value of Osteopontin (SPP1) in colorectal carcinoma requires a personalized molecular approach
Published 2019-09-01“…SPP1 has several isoforms, tissue localizations and molecular functions, signaling pathways, and downstream molecular functions. …”
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12432
Bioinformatics analysis of shared biomarkers and immune pathways of preeclampsia and periodontitis
Published 2025-02-01“…The XG-Boost algorithm was applied to construct diagnostic models to gain insight into disease aetiology. …”
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12433
Microbe-mediated stress resistance in plants: the roles played by core and stress-specific microbiota
Published 2025-05-01“…Through co-occurrence network analysis, the dynamic change networks of microbial communities under the four treatments were constructed, revealing distinct change trajectories corresponding to different treatments. …”
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12434
The mSQUASH is a feasible and valid measurement tool to uniformly assess daily physical activity in patients with rheumatic diseases
Published 2024-10-01“…Fair correlations were found between mSQUASH and Axial Spondyloarthritis Disease Activity Score (ρ=−0.31), Bath Ankylosing Spondylitis Functional Index (ρ=−0.37) and Assessment of SpondyloArthritis International Society-Health Index (ρ=−0.30). …”
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12435
Leveraging a disulfidptosis-based signature to characterize heterogeneity and optimize treatment in multiple myeloma
Published 2025-04-01“…We further explored genetic mutation mapping, protein-protein interactions, functional enrichment, drug sensitivity, drug prediction, and immune infiltration analysis among subtypes and risk subgroups. …”
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12436
Identification of core noncoding RNA-associated competing endogenous RNA networks in renal fibrosis via whole-transcriptome sequencing
Published 2025-12-01“…Enrichment analysis was performed to explore potential functions.Results Sequencing analysis revealed significant dysregulation of ncRNAs in all models compared to the normal group. …”
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12437
Nanobodies and their derivatives: pioneering the future of cancer immunotherapy
Published 2025-06-01“…Nonetheless, their short serum half-life and lack of Fc-mediated functions may limit efficacy, which can be addressed by Fc fusion, albumin binding, or multivalent construct design. …”
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12438
Chromosome-level genome assembly of scalloped spiny lobster Panulirus homarus homarus
Published 2025-05-01“…A total of 25,580 protein-coding genes were predicted, and 99.98% of the genes were functionally annotated using various protein databases. …”
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12439
A Typological Analysis Method for Rural Dwellings: Architectural Features, Historical Transformations, and Landscape Integration: The Case of “Capo Due Rami”, Italy
Published 2025-02-01“…The findings underscore that the morphotype of the dwellings in “Capo Due Rami” derives from the practical demands of agriculture and the functional requirements of rural life, incorporating targeted architectural solutions to address sanitary and environmental concerns. …”
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12440
Mathematical model of the rubber-cord shell of rotation for pneumatic dampers
Published 2019-04-01“…Equilibrium equations are compiled in the form that excludes the emergence of a singularity at special points and does not require special techniques and tools for integration. To construct the constitutive relations reflecting the structural heterogeneity of the material and described by smooth functions of spatial coordinates, the principle of virtual displacements is used. …”
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