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12241
Statistical and Clustering Analysis of Safety Profiles of FDA-Approved Protein Kinase Inhibitors
Published 2024-12-01“…Protein kinases are vital regulators in cell biology, modifying protein functions through phosphorylation. Protein kinase inhibitors (PKIs), which impede these kinases’ activities, have broadened their therapeutic scope from cancer treatment to autoimmune and viral diseases. …”
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12242
Research Progress on Resveratrol Production by Recombinant Engineering Bacteria Fermentation
Published 2025-06-01“…Resveratrol, as a non-flavonoid polyphenol organic compound, has antioxidant, anti-aging, anti-inflammatory, anti-cancer and other functions, and has shown broad application prospects in the food, medicine, and cosmetics industries. …”
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12243
Electronic Conductive Metal–Organic Frameworks for Aqueous Rechargeable Zinc‐Ion Battery Cathodes: Design, Progress, and Prospects
Published 2025-07-01“…Ordinary metal–organic frameworks (MOFs) are characterized by high specific surface areas, large pore channels, and controllable structures and functions, making them suitable for use in ZIB cathodes with good performance. …”
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12244
Comprehensive expression data for two honey bee species, Apis mellifera and Apis cerana japonica
Published 2025-06-01“…Abstract Comprehensive expression datasets were constructed for Apis mellifera and Apis cerana japonica. …”
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12245
Chelated tin halide perovskite for near-infrared neuromorphic imaging array enabling object recognition and motion perception
Published 2025-05-01“…Here, we present lead-free non-toxic formamidinium tin triiodide perovskites functionalized with bio-friendly quercetin molecules via a multi-site chelate strategy, achieving favorable near-infrared response and optoelectronic properties. …”
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12246
Vole Foraging-Inspired Dynamic Path Planning of Wheeled Humanoid Robots Under Workshop Slippery Road Conditions
Published 2025-04-01“…On this basis, the dynamic path-planning model is constructed by combining the cost functions and constraints based on the slip-risk information. …”
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12247
A Simulation-Based Planning Tool for Floating Storage and Regasification Units
Published 2020-11-01“…The objective of this paper was to propose a functional simulation model for the operation of floating storage and regasification units (FSRUs) used for the import of liquefied natural gas (LNG). …”
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12248
The Signatures of Density Fluctuations and Mixing Gas in Circumgalactic Absorption Systems
Published 2025-01-01“…Focusing on these physically motivated models, we parameterize each with a single parameter for simplicity and provide empirical and theoretical estimates for reasonable parameter values. We then construct the probability distribution functions for each of these scenarios, calculate the effective ion fractions, and fit our models to the COS-Halos absorption measurements to infer the gas densities and metallicities. …”
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12249
CAR-T Therapy in HIV: Pioneering Advances and Navigating Challenges
Published 2024-10-01“…We discuss advancements in targeting strategies within CAR constructs and the intricate regulation of T cell proliferation and chemotaxis. …”
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12250
Hot Holographic 2-Flavor Quark Star
Published 2025-06-01“…Furthermore, we illustrate the full parameter maps of the energy density and pressure as functions of the temperature and chemical potential and discuss the constant thermal conductivity case supposing a heat source inside.…”
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12251
Pavement Deterioration Modeling of the International Roughness Index Based on Fuzzy Logic Approach
Published 2025-07-01“…This paper strives to construct a system rooted in fuzzy logic to appraise the requirements for maintenance and (IRI) evaluation within a network of pavement roads. …”
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12252
Electropneumatic Oscillators Using Nonlinear Inflatables
Published 2025-06-01“…The latter is restricted by a complex translation of abstract functions to the physical domain, e.g., negative feedback, if‐then behavior, etc. …”
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12253
Adult Neural Stem Cells: Basic Research and Production Strategies for Neurorestorative Therapy
Published 2018-01-01“…Over many decades, constructing genetically and phenotypically stable lines of neural stem cells (NSC) for clinical purposes with the aim of restoring irreversibly lost functions of nervous tissue has been one of the major goals for multiple research groups. …”
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12254
Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data
Published 2019-08-01“…The data were combined with prior knowledge to construct the first comprehensive logic model of EDN signalling. …”
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12255
Multi‐Omics Analysis Reveals Impacts of LincRNA Deletion on Yeast Protein Synthesis
Published 2025-04-01“…Abstract Non‐coding RNAs (ncRNAs) are widespread across various genomic regions and play a crucial role in modulating gene expression and cellular functions, thereby increasing biological complexity. …”
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12256
Nine high-quality Anas genomes provide new insights into Anas evolution and domestication
Published 2025-04-01“…Furthermore, a long terminal repeat (LTR) retrotransposon burst was found to have accelerated duck domestication, specifically contributing to functional shifts of the notable MITF and IGF2BP1 genes. …”
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12257
Synthesis, characterization and theoretical calculations of Cu(I) complex of trithiocyanuric acid [Cu(ttc)3]
Published 2018-08-01“…A new Cu(I) complex constructed by reaction of trithiocyanuric acid (ttc) and copper (II) perchlorate hexahydrate has been successfully synthesized by a slow sedimentation method in a DMF solvent at room temperature. …”
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12258
The Impact of Urban Form on Carbon Emission Efficiency Under Public Transit-Oriented Development: Spatial Heterogeneity and Driving Forces
Published 2025-05-01“…Taking Shenzhen as a case study with 2022 data, this research constructs a multidimensional indicator system covering land use, functional mix, transportation structure, and spatial layout. …”
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12259
Molecular logic gates based on programmable self-assembly of DNA origami triangles for the detection of nucleic acid molecules
Published 2025-08-01“…By coupling the programmability of DNA nanostructures with molecular recognition logic, the platform constructs autonomous systems capable of interpreting biological signals via predefined algorithms. …”
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12260
Disability as Narrative Prosthesis in Charles Dickens’s A Christmas Carol
Published 2023-01-01“…Rather, they have only functioned as metaphors and symbols that have been constructed to convey a moral message to “normal” characters and readers. …”
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