Large‐scale image‐based profiling of single‐cell phenotypes in arrayed CRISPR‐Cas9 gene perturbation screens by Reinoud de Groot, Joel Lüthi, Helen Lindsay, René Holtackers, Lucas Pelkmans

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Analytical solution of problem of shielding low-frequency magnetic field by thin-walled cylindrical screen in presence of cylinder by G. Ch. Shushkevich

“…Initially the potential of initial magnetic field is represented as spherical harmonic functions, then using addition theorems connecting spherical and cylindrical harmonic functions, it became as cylindrical harmonic functions superposition. …”
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About the confusion-matrix-based assessment of the results of imbalanced data classification by V. V. Starovoitov, Yu. I. Golub

“…It is shown that to represent confusion matrices it is better to use absolute values of object distribution by classes instead of relative ones, since they give an idea of the amount of data tested for each class and their imbalance. When constructing classifiers, it is recommended to evaluate errors by functions that do not depend on the data imbalance, that allows to hope for more correct classification results for real data.…”
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Emotive Vocabulary as a Means of Expressing Axiological Meanings in a Hagiographic Text by Evgeniia G. Dmitrieva

“…The article focuses on the functional and semantic features of the vocabulary of emotions as a means of conveying ideas about spiritual and moral values, the religious and moral ideal. …”
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Interpreting the nature and non‐classical characteristics of information: a labyrinth of research approaches on the threshold of the 21st century by A.A. Kornienko, S.B. Kukhalsky

“…The authors have revealed the difference between the attributive and functional (functional‐cybernetic) concepts of information. …”
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Nonlinear Vibration and Post-Buckling Behaviors of Metal and FGM Pipes Transporting Heavy Crude Oil by Kamran Foroutan, Farshid Torabi, Arth Pradeep Patel

“…Functionally graded materials (FGMs) have the potential to revolutionize the oil and gas transportation sector, due to their increased strengths and efficiencies as pipelines. …”
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Co-Community Network Analysis Reveals Alterations in Brain Networks in Alzheimer’s Disease by Xiaodong Wang, Zhaokai Zhang, Lingli Deng, Jiyang Dong

“…<b>Background</b>: Alzheimer’s disease (AD) is a common neurodegenerative disease. Functional magnetic resonance imaging (fMRI) can be used to measure the temporal correlation of blood-oxygen-level-dependent (BOLD) signals in the brain to assess the brain’s intrinsic connectivity and capture dynamic changes in the brain. …”
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Sensitive Detection of Aflatoxin B1 in Foods Using Aptasensing Based on FGO-Mediated CdTe QDs by Puye Liang, Sihan Liu, Qinqing Han, Kaixuan Zhou, Tiange Li, Xianqing Huang, Lianjun Song, Tianlin Wang

“…In this study, due to the high specific adsorption capacity of AFB₁ aptamers, we applied a sensing strategy based on quantum dots (QDs) and carboxyl-functionalized graphene oxide (FGO) to construct a simple fluorescence quenching platform. …”
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Actual Problems of Development and Improvement of Constitutional Legislation (to the 30th Anniversary of the Constitution of the Russian Federation) by V. E. Sevryugin

“…This underscores the imperative for further reform, not only within the constitutional mechanisms governing the functioning of the state apparatus but also across all branches of government in Russia. …”
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Beyond general food craving: sex differences in food-specific craving identified using item response theory by Daiil Jun, Daiil Jun, Sean Joo, Tera L. Fazzino, Tera L. Fazzino

“…While prior research has predominantly examined food craving as a general construct (e.g., craving for foods overall), this approach may obscure important variability in craving for specific foods. …”
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Characterization of holins, the membrane proteins of coliphage ASEC2201: a genomewide in silico approach by Humaira Saeed, Sudhaker Padmesh, Aditi Singh, Sujeet Pratap Singh, Mohammed Haris Siddiqui, Manodeep Sen, Imran Hussain, Mirza Masroor Ali Beg

“…In silico identification of cell-penetrating peptide motifs within the holin sequences suggests potential for enhanced intracellular delivery in CPP-fusion therapeutic constructs. Overall, our in-depth analysis elucidates the structural and functional properties of ASEC2201 holins, underscoring their biotechnological significance as scaffolds for developing novel antimicrobial strategies against MDR E. coli. …”
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Protocol for a nested case-control study: identifying neuroimaging biomarkers for the progression of subclinical depression and qi-stagnation constitution to major depressive disor... by Jing Wang, Chengfeng Zhang, Yueqi Zhang, Yuanyuan Liu, Jingli Zhang, Xingwei Fang, Wangyang Xia, Yanzhao Xie, Zhongli Lan, Jinhui Wang, Jinhui Wang, Jinhui Wang, Jinhui Wang, Min Lu, Jun Chen, Jun Chen

“…We then divide the 300 adolescents with SD and QSC into two groups based on whether they progress to MDD after one year. Functional brain networks will be constructed based on 400 regions of interest (ROIs). …”
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Dynamic 3D-Network Coating Composite Enables Global Isolation of Phosphopeptides, Stepwise Separation of Mono- and Multi-Phosphopeptides, and Phosphoproteomics of Human Lung Cells by Linlin Liu, Zhenhua Chen, Danni Wang, Weida Liang, Binbin Wang, Chenglong Xia, Yinghua Yan, Chuanfan Ding, Xiaodan Meng, Hongze Liang

“…The outer functional 3D-network layer was prepared by free radical polymerization of the phosphonate-functionalized vinyl imidazolium salt monomer and subsequent metal immobilization. …”
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Boosting electrocatalytic generation of FDCA and H2 from 2,5-furanedimethanol solution by carbonized wood supported Fe-CoP nanoleaves by Yuan Ma, Jiaojiao Miao, Yuanyuan Li, Xuehua Zhou, Lianbing Zhang, Jian Zhang, Guanglei Li, Yong Qin, Jie Gao

“…Herein, the effectiveness of Fe-CoP in catalyzing FDM oxidation was demonstrated by density functional theory (DFT) calculations and experiments, and a renewable carbonized porous wood decorated with Fe-doped CoP nanoleaves (Fe-CoP/CW) was constructed for electrocatalytic FDCA and hydrogen generation. …”
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Mild Zika Virus Infection in Mice Without Motor Impairments Induces Working Memory Deficits, Anxiety-like Behaviors, and Dysregulation of Immunity and Synaptic Vesicle Pathways by Jaime Alexander Chivatá-Ávila, Paola Rojas-Estevez, Alejandra M. Muñoz-Suarez, Esthefanny Caro-Morales, Aura Caterine Rengifo, Orlando Torres-Fernández, Jose Manuel Lozano, Diego A. Álvarez-Díaz

“…The infection induced mild cognitive behavioral changes, though motor and motivational functions remained unaffected. These cognitive changes were linked to the functional repression of synaptic vesicles and alterations in neuronal structure, suggesting potential disruptions in neuronal plasticity. …”
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Bioinformatics&amp;#x2011;Based Analysis Reveals Diagnostic Biomarkers and Immune Landscape in Atopic Dermatitis by Yang M, Zhang X, Zhou C, Du Y, Zhou M, Zhang W

“…A competing endogenous RNA (ceRNA) network involving lncRNA-miRNA-mRNA interactions for the key gene ECSIT was also constructed.Conclusion: ECSIT, LRFN5, and USP16 represent promising diagnostic biomarkers for AD and are involved in immune cell infiltration, providing new insights into AD pathogenesis.Keywords: atopic dermatitis, AD, gene expression analysis, immune cell infiltration, functional enrichment analysis, Mendelian randomization analysis…”
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The role of JPT1 in hepatocellular carcinoma: tumor progression, microtubule dynamics regulation, and potential mechanisms within the immune microenvironment by Yipin Lu, Peng Xu, Sha Li, Jie Yao

“…Differentially expressed gene (DEG) analysis, functional enrichment analysis (GSEA and KEGG), and spatial transcriptomics were utilized to explore the biological functions and mechanisms of JPT1 in tumor biology. …”
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Interfacial charge transfer induced dual- active-sites of RuO2-NiO/NF electrode for high efficiency electrocatalytic hydrogen evolution by CHEN Hui, LIU Xuehua, LIN Yan, CHEN Song, WANG Weiguo

“…Characterization， testing， and density functional theory （DFT） calculations reveal that the heterostructural interface formed by the binding of RuO2 and NiO significantly enhances catalyst performance. …”
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Controllability Analysis and Optimization of Hydrocannon Nozzle Shape Based on Direct Extreme Approach by V. K. Tolstykh, Yu. V. Dmitruk

“…This approach allowed us to identify the conditions for the existence of the gradient of the objective functional and construct a regularization of the solution to the inverse problem using adaptive gradient methods. …”
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Realizing Environmentally Scalable Pre-Lithiation via Protective Coating of LiSi Alloys to Promote High-Energy-Density Lithium-Ion Batteries by Yinan Liu, Wei Jiang, Congcong Zhang, Pingshan Jia, Zhiyuan Zhang, Yun Zheng, Kunye Yan, Jun Wang, Yunxian Qian, Junpo Guo, Rong Chen, Yike Huang, Yingying Shen, Lifen Long, Bang Zheng, Huaiyu Shao

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