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Alterations of white matter functional networks in pediatric drug-resistant temporal lobe epilepsy: A graph theory analysis study
Published 2025-07-01“…We included 91 children (43 with DRTLE and 48 healthy controls), acquiring structural and functional MRI data to construct WM functional networks. …”
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Disrupted small-world architecture and altered default mode network topology of brain functional network in college students with subclinical depression
Published 2025-03-01“…However, the brain network topology of ScD remains poorly understood, impeding our comprehension of the neuropathology underlying ScD. Methods Functional networks of individuals with ScD (n = 26) and healthy controls (HCs) (n = 33) were constructed based on functional magnetic resonance imaging data. …”
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2505
Event Rate Density and Luminosity Function of Newborn-magnetar-driven X-Ray Transients from Neutron Star Binary Mergers
Published 2025-01-01“…Utilizing population synthesis calculations incorporating various equations of state (EoSs), we derive a local ERD of ∼300 Gpc ^−3 yr ^−1 and a redshift-dependent ERD profile peaking at z = 1.81 followed by a rapid decline beyond z ∼ 4. Constructing an XT sample based on CDF-S and Swift observations, we characterize the LF by a single power-law function at L ≤ 4.75 × 10 ^46 erg s ^−1 with a slope of −1.03, followed by a broken power-law function in which the break luminosity is L _b = 4.38 × 10 ^47 erg s ^−1 and the slopes are −0.28 and −1.66. …”
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2508
A novel approach to multi-objective portfolio selection: modeling emerging financial markets using satisfaction functions and fuzzy values
Published 2024-11-01“…In other words, the proposed model outperformed the base model in all the objectives under study.Originality/Value: As distinguishing features of the proposed model of this research, one can mention: 1) constructing and using fuzzy distribution functions and calculating ideal values and expected ranges for all desired objectives considering the conditions of the examined market research using simple mathematical modeling, 2) utilizing the experience of financial market experts in planning model for selecting suitable investment portfolios in emerging financial markets, 3) presenting an approach to calculating portfolio risk in conditions of information scarcity in the problem environment using fuzzy theory, 4) development of the fuzzy benchmark-criterion method for weighting the objectives under study in the problem considering the expertise of financial market experts, and 5) simple modeling, considering interval fuzzy values in the model, and being usable for all individuals with different levels of investment knowledge.…”
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2509
Broad-line AGNs at 3.5 < z < 6: The Black Hole Mass Function and a Connection with Little Red Dots
Published 2025-01-01“…We find that ∼90% of LRD BLAGNs are intrinsically reddened ( β _opt > 0), independent of contributions from emission lines to the broadband photometry. We construct the black hole (BH) mass function at 3.5 < z < 6 after computing robust completeness corrections. …”
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2510
The sucrose synthase gene family in blueberry (Vaccinium darrowii): functional insights into the role of VdSUS4 in salt stress tolerance
Published 2025-06-01“…Phylogenetic analysis, constructed through a multi-species phylogenetic tree, revealed that the SUS gene family can be categorized into three subfamilies: SUS I, SUS II and SUS III. …”
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2511
A Structural Model of Truncated Gaussia princeps Luciferase Elucidating the Crucial Catalytic Function of No.76 Arginine towards Coelenterazine Oxidation.
Published 2025-01-01“…Moreover, R76, a validated activity-critical amino acid residue, resides in the cavity and forms a stable hydrogen bond with CTZ. Then, we constructed a cluster model to examine the CTZ oxidation pathway in the cavity using Density Functional Theory (DFT) calculations. …”
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Functional Characterization of <i>FgAsp</i>, a Gene Coding an Aspartic Acid Protease in <i>Fusarium graminearum</i>
Published 2024-12-01“…In this study, <i>FGSG_09558</i> was found to contain a conserved structural domain and signal peptide sequence of aspartic acid protease and was therefore named <i>FgAsp</i>. The function of <i>FgAsp</i> in <i>F. graminearum</i> was investigated by constructing the knockout and complementation mutants of this gene. …”
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2514
Syn-MolOpt: a synthesis planning-driven molecular optimization method using data-derived functional reaction templates
Published 2025-03-01“…To address this issue, we first developed a general pipeline capable of constructing functional reaction template library specific to any property where a predictive model can be built. …”
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2515
The Joint Action of Metal and Enzymatic Nanoparticles Used for Functionalization of Protective Self-Cleaning Materials Neutralizing Organophosphates and Possessing Bactericide A...
Published 2023-10-01“…The combination of several modules, including metal nanoparticles (tantalum or zinc), antimicrobial substances, enzyme nanocomplexes that provide self-purification (self-degassing) and multiple functionalization, makes it possible to create materials that provide protection against chemical and biological damaging agents. …”
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2516
Identification and functional characterization of T-cell exhaustion-associated lncRNA AL031775.1 in osteosarcoma: a novel therapeutic target
Published 2025-02-01“…A six-lncRNA prognostic model was established using LASSO regression and validated in separate cohorts. Functional assays evaluated the impact of the lncRNA AL031775.1 on osteosarcoma cell behavior and T-cell function.ResultsTwenty-four key T-cell exhaustion-related genes were identified and significantly enriched in immune-related pathways, indicating their importance in the osteosarcoma immune microenvironment. …”
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A risk prediction model for poor joint function recovery after ankle fracture surgery based on interpretable machine learning
Published 2025-06-01“…SHAP analysis showed that functional exercise compliance, combined ligament injury, and open fracture accounted for the largest proportion of SHAP values and were the most important influencing factors.ConclusionThrough evaluation and comparison of the developed models, the lasso-stacking model demonstrated the best performance and is more suitable for predicting joint function recovery after ankle surgery. …”
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2519
Assessing hand motor function in chronic immune-mediated neuropathies: a proof-of-concept study using a data glove
Published 2024-12-01“…., reliability, objectivity) or functional relevance. Wearables such as data gloves might be helpful, allowing repeated quantification of complex everyday life-relevant motor function of the hand. …”
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2520
Adaptation and psychometric evaluation of the Chinese version of the hip disability and osteoarthritis outcome Score–Physical function Short-form (HOOS-PS)
Published 2025-08-01“…Abstract Background Chronic hip joint disease has a high prevalence in China, and the primary scale currently used to assess functional recovery after total hip arthroplasty (THA) is the Hip disability and Osteoarthritis Outcome Score - Physical Function Short-form (HOOS-PS). …”
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