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2261
Study on individual differences in visual working memory tasks based on spatiotemporal brain functional metrics and biological perspectives
Published 2025-06-01“…This study investigates individual differences in VWM performance across four types of visual stimuli (Body, Face, Place, Tool) under 0-back and 2-back conditions by integrating gene expression data and spatiotemporal brain function metrics. First, multiple spatiotemporal brain function metrics were extracted, and Sequential Backward Selection (SBS) and Leave-One-Subject-Out Cross-Validation (LOSO-CV) linear regression were applied to predict behavioral performance under VWM conditions. …”
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2262
A fusion analytic framework for investigating functional brain connectivity differences using resting-state fMRI
Published 2024-12-01“…The framework involves three steps: first, constructing ROI-based Functional Connectivity Networks (FCNs) to manage resting-state fMRI data; second, employing a Self-Attention Deep Learning Model (Self-Attn) for binary classification to generate attention distributions encoding group-level differences; and third, utilizing a Latent Space Item-Response Model (LSIRM) to extract group-representative ROI features, visualized on group summary FCNs.ResultsWe applied our framework to analyze four types of cognitive impairments, demonstrating their effectiveness in identifying significant ROIs that contribute to the differences between the two disease groups. …”
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2263
A simple pedotransfer function to estimate fine fraction organic carbon contents of surface horizons in French soils
Published 2025-07-01“…Using the knowledge gained from the exploratory analysis, we constructed a simple pedotransfer function. A slight inflection in the OCfine content was detected with increasing SOC content and a good approximation of OCfine content was reached using a second-degree polynomial relationship, with distinct coefficients depending on the land cover (i.e., croplands and permanent crops, grasslands, natural grasslands, and forests and shrubs). …”
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2264
Accuracy and reliability of non-invasive pressure-strain loop for myocardial work assessment in functional single ventricle patients
Published 2025-08-01“…Abstract Background In biventricular circulation, myocardial work indices derived from pressure-strain loops (PSL) show potential for effectively evaluating ventricular function in both left and right ventricles. However, these novel myocardial work parameters have not been extensively investigated in patients with functional single ventricle (FSV). …”
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2265
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2266
Integrated multiomics analysis identifies PHLDA1+ fibroblasts as prognostic biomarkers and mediators of biological functions in pancreatic cancer
Published 2025-07-01“…However, the prognostic and functional contributions of distinct CAF subtypes remain inadequately understood. …”
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2267
426 Developing a Molecular Toolkit to define NEK functions in triple-negative breast cancer (TNBC) biology
Published 2025-04-01“…Basal NEK protein levels were determined by immunoblot across a panel of cell lines, including breast cancer, osteosarcoma, hepatocellular carcinoma, and non-cancerous cells, to identify appropriate systems for evaluation of NEK function. Doxycycline-inducible cell lines were generated by transduction with lentiviral stocks of NEK shRNA and overexpression constructs and antibiotic selection. …”
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2268
High-density lipoprotein cholesterol subfraction HDL2 is associated with improved endothelial function in systemic lupus erythematosus
Published 2024-05-01“…Flow-mediated dilatation (FMD) is an established non-invasive assessment of vascular endothelial function. Lipoprotein subfractions may be better predictors of FMD than conventional cholesterol measurements. …”
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2269
Dynamic changes in the gastrointestinal microbial communities of Gangba sheep and analysis of their functions in plant biomass degradation at high altitude
Published 2025-01-01“…The identification of dynamic changes in the gastrointestinal microbial communities and their functions is an important step towards improving animal production performance and health. …”
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2270
PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
Published 2025-07-01“…This interaction is dependent on the C1QBP N-terminus (aa 1–167) rather than the known functional domain. Point mutation in C1QBP (T76A/G78N) disrupting predicted hydrogen bonding with PA28γ-D177 significantly reduced their binding. …”
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2271
Integrated bioinformatics and functional studies identify CDK9 as a potential prognostic biomarker and therapeutic target in AML
Published 2025-06-01“…Results Bioinformatics analysis revealed significantly elevated CDK9 expression in AML samples, which correlated with poor patient prognosis. Functional enrichment analysis indicated that CDK9 is involved in key pathways related to cell proliferation, differentiation, and the tumor microenvironment. …”
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2272
Decoding Land Use Conflicts: Spatiotemporal Analysis and Constraint Diagnosis from the Perspectives of Production–Living–Ecological Functions
Published 2024-12-01“…Currently, China’s spatial development is gradually transitioning towards the coordinated development of production, living, and ecological functions (PLEFs). Previous studies have typically focused on land use conflicts from a micro perspective, examining conflicts between production, living, and ecological land uses at a fine scale. …”
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2273
Relationship between renal function and cognitive impairment in patients with stable schizophrenia: a multicenter cross-sectional study
Published 2025-05-01“…Covariate-adjusted linear and multivariate logistic regression models were constructed to determine the relationship between renal function and cognitive function. …”
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2274
Effects of temperature and time treatment on soil characteristics and wheat growth
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2275
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2276
Accounting for asymmetries in cleft sentence use
Published 2024-12-01“… Cleft constructions exhibit variations in their frequency of usage, influenced by different constraints and preferences at various levels, such as syntax or function. …”
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2277
REGULAR METHOD FOR SYNTHESIS OF BASIC BENT-SQUARES OF RANDOM ORDER
Published 2016-08-01“…The paper is devoted to the class construction of the most non-linear Boolean bent-functions of any length N = 2k (k = 2, 4, 6…), on the basis of their spectral representation – Agievich bent squares. …”
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2278
Computational Design and Bioinformatic Insights into Recombinant Whey Protein Production
Published 2025-07-01“…Codon-optimized gene constructs were designed and validated through computational tools, showing enhanced translational efficiency, structural stability, and functional potential. …”
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