Neural Network Ensemble to Detect Dicentric Chromosomes in Metaphase Images by Ignacio Atencia-Jiménez, Adayabalam S. Balajee, Miguel J. Ruiz-Gómez, Francisco Sendra-Portero, Alegría Montoro, Miguel A. Molina-Cabello

“…Further, dicentric chromosome scoring constitutes a bottleneck when several hundreds of samples need to be analyzed for dose estimation in the aftermath of large-scale radiological/nuclear incident(s). …”
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Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B. by Yukio Yamamoto, Rick Moore, Richard A Flavell, Binfeng Lu, Masahiko Negishi

“…PB activates nuclear xenobiotic receptor Constitutive Active/Androstane Receptor (CAR; NR1I3) and this activation is shown to determine PB promotion of HCC in mice. …”
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Characterization of Novel Multifunctional Xylanase from Rumen Metagenome and Its Effects on In Vitro Microbial Fermentation of Wheat Straw by Moguang Zhang, Qinghua Qiu, Xianghui Zhao, Kehui Ouyang, Chanjuan Liu

“…The enzyme’s various functions responded uniquely to metal ions; notably, the addition of 5 mM K⁺ significantly boosted the activities of xylanase, exoglucanase, and endoglucanase by 55.5%, 53.5%, and 16.4%, respectively, without affecting its acetyl esterase activity. …”
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The impact of vision impairment on depressive symptoms among older adults: The mediating role of dispositional optimism. by Xi Ji, Yujie Zhang

“…<h4>Background</h4>Vision impairment, beyond constituting a sensory deficit, fundamentally disrupts older adults' autonomy, emotional regulation, and social participation. …”
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An Efficient Process for the Management of the Deterioration and Conservation of Architectural Heritage: The HBIM Project of the Duomo of Molfetta (Italy) by Enrique Nieto-Julián, Silvana Bruno, Juan Moyano

“…To make multidisciplinary conservation work more flexible, specific properties have been created for the identification and analysis of the degradation detected in the structures, with the HBIM project constituting a manager of the control and inspection activities. …”
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Evaluation of the combined effects of manganese and thermal stress on the metabolic capacities of Arctic charr (Salvelinus alpinus) by Camille Garnier, Pierre U. Blier, Patrice Couture

“…These results suggest that Mn, combined with high temperature, may affect mitochondrial function leading to a decrease in aerobic capacity. …”
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Cardiac and Digestive Forms of Chagas Disease: An Update on Pathogenesis, Genetics, and Therapeutic Targets by Amanda Farage Frade, Hélléa Guérin, Joao Paulo Silva Nunes, Luiz Felipe Souza e Silva, Vinicius Moraes de Paiva Roda, Rafael Pedro Madeira, Pauline Brochet, Pauline Andrieux, Jorge Kalil, Christophe Chevillard, Edecio Cunha-Neto

“…IFN-γ and TNF-α signaling, which are constitutively upregulated in Chagas disease patients, negatively affect mitochondrial function and adenosine 5′-triphosphate (ATP) production–cytokine-induced mitochondrial dysfunction. …”
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Exploring the molecular characteristics of inflammatory bowel disease from the perspective of hypoxia-related genes by Lei Zheng, Lin Mou, Lingying Hao, Rui Chen, Yifei Wang, Miao Yu, Xueyan Zhang

“…BackgroundInflammatory bowel disease (IBD) constitutes a chronic inflammatory disorder affecting the gastrointestinal tract, characterized by a multifaceted pathogenesis that encompasses genetic, environmental, and immunological influences. …”
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A New Ground-Motion Prediction Model for Shallow Crustal Earthquakes in Türkiye by Ulubey Çeken, Fadime Sertçelik, Abdullah İçen

“…Additionally, a heteroscedastic model was created for aleatory variability as a function of <i>M_W</i>. The closest distance to the surface projection of the fault plane (<i>R_JB</i>) is between 0 and 350 km. …”
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Anti-reflux surgical treatment for Barrett’s oesophagus by B. F. Shevchenko, N. V. Prolom, O. M. Babii, S. O. Tarabarov, O. V. Zeleniuk

“…Anti-reflux procedures constituted the second stage to remove HH and restore an excessive dilatation of the esophageal orifice of the diaphragm by cruroraphy with correction of anti-reflux function of the cardia by fundoplication, angle of His reconstruction and providing free food passage. 11 (19.6 %) patients underwent surgery according to a new technique that provided reliable recovery of cardia physiological functions and preservation of the anatomical relation between the diaphragm and the esophageal-gastric junction and included cruroraphy and fundoplication. …”
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Glucocorticoid receptor gene (NR3C1) methylation, childhood maltreatment, multilevel reward responsiveness and depressive and anxiety symptoms: A neuroimaging epigenetic study by Yajing Xu, Shan Yang, Cong Cao

“…Background: Although epigenomic and environment interactions (Epigenome × Environment; Epi × E) might constitute a novel mechanism underlying reward processing, direct evidence is still scarce. …”
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Resisting While Producing: Do-It-Yourself Ethics in Turkiye’s Punk Scene by Ece N. Alparslan, Şengül İnce

“…Scott (1992/2014) stated that the main function of subcultures is to be a space in which people can distribute opposing discourses freely and without fear. …”
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Genome-wide microsatellite characterization and their marker development and transferability in Broussonetia Species by Xiaowen Jia, Hanyu Li, Ying Han, Lu Wang, Chanjuan Lai, Xi Liu, Pan Li, Zupei Lei, Yonghua Zhang

“…Genic-mapped SSRs may regulate biological processes by influencing gene activity and protein function. To verify SSRs polymorphism, we selected 30 ones from 10,752 potentially polymorphic SSRs loci for PCR amplification among these three species, all of which were successfully amplified and exhibited polymorphism across these three species. …”
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Exploring the distinctive characteristics of gut microbiota across different horse breeds and ages using metataxonomics by Xinxi Qin, Li Xi, Longfei Zhao, Jincheng Han, Hongxia Qu, Yajun Xu, Weiping Weng

“…BackgroundGut microbiota exerts a pivotal function in host nutrient metabolism and maturation of the mucosal immunity. …”
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BIN1 localizes the L-type calcium channel to cardiac T-tubules. by Ting-Ting Hong, James W Smyth, Danchen Gao, Kevin Y Chu, Jacob M Vogan, Tina S Fong, Brian C Jensen, Henry M Colecraft, Robin M Shaw

“…However, the functional role of BIN1 in cardiomyocytes is not known. …”
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Realismo y antirrealismo en la concepción semántica de las teorías científicas by León Olivé

“…So, if the empirical basis is constituted by applications, but in turn these are seen as parts of theories, she is committed to the view that theories must be tested against structures which are constitutive parts of themselves. …”
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Structural basis for hepatitis B virus restriction by a viral receptor homologue by Kaho Shionoya, Jae-Hyun Park, Toru Ekimoto, Junko S. Takeuchi, Junki Mifune, Takeshi Morita, Naito Ishimoto, Haruka Umezawa, Kenichiro Yamamoto, Chisa Kobayashi, Atsuto Kusunoki, Norimichi Nomura, So Iwata, Masamichi Muramatsu, Jeremy R. H. Tame, Mitsunori Ikeguchi, Sam-Yong Park, Koichi Watashi

“…To reveal how mNTCP loses the viral receptor function, we here solve the cryo-electron microscopy structure of mNTCP. …”
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CRISPR screens identify tumor‐promoting genes conferring melanoma cell plasticity and resistance by Arthur Gautron, Laura Bachelot, Marc Aubry, Delphine Leclerc, Anaïs M Quéméner, Sébastien Corre, Florian Rambow, Anaïs Paris, Nina Tardif, Héloïse M Leclair, Oskar Marin‐Bejar, Cédric Coulouarn, Jean‐Christophe Marine, Marie‐Dominique Galibert, David Gilot

“…Here, we performed in vivo gain‐of‐function CRISPR screens and identified SMAD3, BIRC3, and SLC9A5 as key actors of BRAFi resistance. …”
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GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus by Danying Chen, Zhifei Hou, Dong Jiang, Mei Zheng, Guoli Li, Yue Zhang, Rui Li, Hanxin Lin, Jinhong Chang, Hui Zeng, Ju-Tao Guo, Xuesen Zhao

“…Specifically, we demonstrated that GILT was constitutively expressed in lung epithelial cells and fibroblasts and its expression could be further induced by type II interferon. …”
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Characterization of spreading depolarizations in swine following superior sagittal sinus occlusion: a novel gyrencephalic model study by Renan Sanchez-Porras, Francisco L. Ramírez-Cuapio, Mildred A. Gutiérrez-Herrera, Ángel Alberto Puig-Lagunes, Pablo Albiña-Palmarola, Juan M. López-Navarro, Marcos Alejandro Suárez-Gutiérrez, Roberto Díaz-Peregrino, Diego A. Sandoval-Lopez, Gregor Fischer, Farzam Vazifehdan, Johannes Woitzik, Edgar Santos

“…Abstract Cerebral sinus thrombosis, which constitutes a small percentage of all strokes, usually affects young individuals and can lead to venous stroke. …”
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