Tracking Long-Term Ozone Pollution Dynamics in Chinese Cities with Meteorological and Emission Attribution by Hongrui Li, Xiaoyong Liu, Zijian Liu, Mengyang Li, Tong Wu, Peicheng Li, Peng Zhou

“…Although China has achieved substantial reductions in particulate matter pollution, continually rising ground-level ozone now constitutes the primary challenge to further air-quality improvements. …”
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A Novel YWHAG Variant L173S Causes Developmental and Epileptic Encephalopathy by Disrupting the Hydrophobic Internal Protein Structure by Yuan Jin, Qian Niu, Shan Na Liang, Mei Ling Luo, Xiao Lin Su, Zhe Tao

“…This may provide insights into the functional mechanisms of YWHAG and potential therapeutic strategies.…”
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Cross-cultural adaptation, reliability and validity analysis of the Cantonese-Chinese Manchester Oxford Foot Questionnaire for Foot and Ankle Disorder (Manchester-Oxford Foot Quest... by Shu MC Chia, Leung P Ho, Violet Man-Chi Ko, He Xin, Long CB Chow, Patrick Shu-Hang Yung, Samuel Ka-Kin Ling

“…The overall reliability coefficient constituted 0.86 (intraclass correlation coefficient = 0.72–0.93). …”
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Rasism i seminarierummet: Strategisk empati och de svåra känslornas pedagogik by Magnus Rodell

“…The text concludes with a discussion of Michalinos Zembyla’s concepts of strategic empathy and reconciliatory perspective. Although this constitutes a difficult-to-navigate pedagogical methodology, the concepts can function as tools to tackle difficult and emotionally invested seminar situations.  …”
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The exocyst complex controls multiple events in the pathway of regulated exocytosis by Sofía Suárez Freire, Sebastián Perez-Pandolfo, Sabrina Micaela Fresco, Julián Valinoti, Eleonora Sorianello, Pablo Wappner, Mariana Melani

“…Eukaryotic cells depend on exocytosis to direct intracellularly synthesized material toward the extracellular space or the plasma membrane, so exocytosis constitutes a basic function for cellular homeostasis and communication between cells. …”
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CD36 promotes iron accumulation and dysfunction in CD8 T cells via the p38-CEBPB-TfR1 axis in earlystage hepatocellular carcinoma by Yifei Qin, Fei Huo, Zhuan Feng, Jialu Hou, Yaxin Ding, Quancheng Wang, Yu Gui, Ziwei Yang, Jiali Yang, Gang Zhou, Ling Li, Jianli Jiang, Lingmin Kong, Shijie Wang, Gang Nan, Dingqiao Xu, Xiaohang Xie, Lijuan Wang, Qian He, Ruibin Yang, Peng Lin, Huijie Bian, Zhi-Nan Chen, Jiao Wu

“…Depletion of CD36 in CD8+ T cells inhibited the upregulation of TfR1 and the increase of iron levels. Furthermore, constitutively activated nuclear factor erythroid 2-related factor 2 (NRF2) effectively suppressed lipid peroxidation, thereby preserving the effector functions of intratumoral CD8+ T cells and ultimately inhibiting tumor growth. …”
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Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria by Stephanie I Studniberg, Lisa J Ioannidis, Retno A S Utami, Leily Trianty, Yang Liao, Waruni Abeysekera, Connie S N Li‐Wai‐Suen, Halina M Pietrzak, Julie Healer, Agatha M Puspitasari, Dwi Apriyanti, Farah Coutrier, Jeanne R Poespoprodjo, Enny Kenangalem, Benediktus Andries, Pak Prayoga, Novita Sariyanti, Gordon K Smyth, Alan F Cowman, Ric N Price, Rintis Noviyanti, Wei Shi, Alexandra L Garnham, Diana S Hansen

“…Emerging views suggest that these infections are detrimental and constitute a parasite reservoir that perpetuates transmission. …”
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Microenvironmental alkalization promotes the therapeutic effects of MSLN-CAR-T cells by Jie Liu, Jun Wang, Min Wu, Ling Mao, Jianjun Li, Xuejia Zhai, Junhan Wang, Langhong Li, Jiangjie Duan, Shuang Lin, Shicang Yu

“…Moreover, mechanistic exploration revealed that the attenuation of autophagy-lysosome function caused by microenvironmental alkalization inhibited the degradation of MSLN. …”
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A single-nucleus RNA sequencing atlas of the postnatal retina of the shark Scyliorhinus canicula by Nicolás Vidal-Vázquez, Ismael Hernández-Núñez, Pablo Carballo-Pacoret, Sarah Salisbury, Paula R. Villamayor, Francisca Hervas-Sotomayor, Xuefei Yuan, Francesco Lamanna, Céline Schneider, Julia Schmidt, Sylvie Mazan, Henrik Kaessmann, Fátima Adrio, Diego Robledo, Antón Barreiro-Iglesias, Eva Candal

“…Abstract The retina, whose basic cellular structure is highly conserved across vertebrates, constitutes an accessible system for studying the central nervous system. …”
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Effects of acupuncture on the signs and symptoms of people with rheumatic diseases: A scoping review by Mariane Elivânia Silva, Evelin Beatriz Bezerra de Melo, Maria Améllia Lopes Cabral, Laura Lima Souza, Silmara de Oliveira Silva, Nahadja Tahaynara Barros Leal, Jucielly Ferreira da Fonseca, Rodrigo Assis Neves Dantas, Daniele Vieira Dantas

“…Introduction: Rheumatic diseases constitute a wide range of chronic diseases that mainly affect the musculoskeletal system. …”
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Unraveling the triad of immunotherapy, tumor microenvironment, and skeletal muscle biomechanics in oncology by Shuang Ma, Ying Lu, Shang Sui, Jia-shuo Yang, Bing-bing Fu, Pei-xin Tan, Yicheng Chai, Jiaqi Lv, Lingyu Kong, Xiaolin Wu, Yi-bo Gao, Tao Yan

“…The intricate interaction between skeletal muscle biomechanics, the tumor microenvironment, and immunotherapy constitutes a pivotal research focus oncology. This work provides a comprehensive review of methodologies for evaluating skeletal muscle biomechanics, including handheld dynamometry, advanced imaging techniques, electrical impedance myography, elastography, and single-fiber experiments to assess muscle quality and performance. …”
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Flavones enrich rhizosphere Pseudomonas to enhance nitrogen utilization and secondary root growth in Populus by Jiadong Wu, Sijia Liu, Haoyu Zhang, Sisi Chen, Jingna Si, Lin Liu, Yue Wang, Shuxian Tan, Yuxin Du, Zhelun Jin, Jianbo Xie, Deqiang Zhang

“…Abstract Plant growth behavior is a function of genetic network architecture. The importance of root microbiome variation driving plant functional traits is increasingly recognized, but the genetic mechanisms governing this variation are less studied. …”
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Dimeric natural product panepocyclinol A inhibits STAT3 via di-covalent modification by Li Li, Yuezhou Wang, Yiqiu Wang, Xiaoyang Li, Qihong Deng, Fei Gao, Wenhua Lian, Yunzhan Li, Fu Gui, Yanling Wei, Su-Jie Zhu, Cai-Hong Yun, Lei Zhang, Zhiyu Hu, Qingyan Xu, Xiaobing Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Fei Xia, Xianming Deng

“…Furthermore, PecA exhibits high efficacy against anaplastic large T cell lymphoma in vitro and in vivo, especially those with constitutively activated STAT3 or STAT3Y640F. In summary, our study describes a distinct and effective di-covalent modification for the dimeric compound PecA to disrupt STAT3 function.…”
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Navigating the future landscape of uterine fibroid research: a comprehensive summary of patient-centered outcome measures and implications by Shuhao Yang, Qing Yan, Fei Liu, Wei Yan, Suzhen Yuan, Minli Zhang, Ya Li, Zhangying Wu, Tao Xiang, Wenwen Wang

“…Abstract Background Uterine fibroid constitutes a significant burden for affected women and research in this area has increasingly focused on patient-centered outcomes, with patient-reported outcome measures (PROMs) becoming crucial in related studies. …”
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Heavy metals in the diet: unraveling the molecular pathways linked to neurodegenerative disease risk by Patricia Guevara-Ramírez, Rafael Tamayo-Trujillo, Santiago Cadena-Ullauri, Viviana Ruiz-Pozo, Elius Paz-Cruz, Giuseppe Annunziata, Ludovica Verde, Evelyn Frias-Toral, Daniel Simancas-Racines, Ana Karina Zambrano

“…Neurodegenerative diseases (NDDs) affect millions of lives worldwide. They constitute a group of neurological disorders with shared common features, including impaired cognition, behavior, memory, and motor functions. …”
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Development of new albumin-binding radiotracers for PET imaging of cerebrospinal fluid flow in the glymphatic system by Martta Peltoniemi, Surachet Imlimthan, Sonja C. Jalonen, Niklas Daniel Åke Persson, Terhi J. Lohela, Tuomas O. Lilius, Mirkka Sarparanta

“…Abstract Background The glymphatic system is a recently discovered brain-wide clearance system that allows the cerebrospinal fluid (CSF) flow to clear metabolic waste, but the tools for the quantitative and non-invasive investigation of its function and activity especially in humans is lacking, hindering studies on glymphatic system physiology and therapeutic potential of glymphatic drug delivery and modulation. …”
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El principio de universalización y la razón práctica (2a. parte) by Osvaldo Guariglia

“…This analysis once completed, I will examine (II) the function of the principle in the field of moral judgements and its main role as ultimate rule of practical reason to which it grants its peculiar form of objectivity. …”
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Use Efficiency, Reduction Potential, and Effects of Fertilizers on Carbon Emissions in China’s Major Citrus Regions by Yueyuan Yang, Chunjie Qi, Yumeng Gu, Guozhu Fang

“…Enhancing the efficiency of fertilizer utilization and advancing fertilizer reduction efforts constitutes a pivotal initiative for augmenting the quality and productivity of the citrus industry; this constitutes an indispensable prerequisite for attaining green and sustainable development. …”
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LL-37 Attenuates Sepsis-Induced Lung Injury by Alleviating Inflammatory Response and Epithelial Cell Oxidative Injury via ZBP1-Mediated Autophagy by Hu Gao, Fajuan Tang, Bin Chen, Xihong Li

“…Inflammation and oxidative stress constitute key pathological mechanisms in ALI caused by sepsis. …”
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Efficacy and safety of Chinese patent medicines for allergic rhinitis based on 2020 Chinese Pharmacopoeia: a protocol for systematic review and meta-analysis of randomized controll... by Weibo Zhao, Lingyao Kong, Xuehui Wang, Qingyuan Liu, Yaqi Wang, Ji Wang

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