Innovative Strategies For Social-Economic Development Financial Strategies In The Development Country by Chukwu Anthony Ogochukwu, Karina Kasztelnik

“…This research paper summarizes the arguments and counterarguments within the scientific discussion on the Small and medium scale enterprises constitute the backbone of any nations economic development and had remained a major contributor in poverty alleviation, employment generation, and industrialization. …”
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SENP5 promotes endometrial cancer cell growth by regulating β-catenin deSUMOylation to enhance GPX4-resistance to ferroptosis by Ziyuan Wang, Yongmei Zhang, Yongfang Zhang, Qiuhong Deng, Yandong Xi, Wanxia He, Xiaolong Ma

“…Nonetheless, the function of SENP5 in EC and its regulation of EC progression through the related mechanism of desumoylation modification remain elusive. …”
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GATOR1 gene variants in focal epilepsy by Kovačević Maša, Vojvodić Nikola, Novaković Ivana

“…The genes listed above code the three subunits that comprise the GTPase-activating protein (GAP) activity towards Rags 1 (GATOR1) complex, a negative regulator of the mechanistic target of rapamycin (mTOR) complex 1 (mTORC1). Loss of function of GATOR1 leads to constitutive mTORC1 activation that is linked to various malformations of cortical development (MCD), most notoriously focal cortical dysplasia (FCD), but has also been linked to epilepsy in the absence of overt MCD. …”
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PRODUCTIVITY AND EFFICIENCY OF MAIZE (ZEA MAYS) FARMERS IN ADAMAWA STATE, NIGERIA by Abdu Karniliyus TASHIKALMA, Dengle Yuniyus GIROH

“…Furthermore, the stochastic cost function analysis indicated that 80.24% variations in allocative efficiencies were as a result of the variables included in the model. …”
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THE PROPOSAL MODEL OF RATIONAL WORKFORCE ASSIGNMENT IN DOKUZ EYLUL UNIVERSITY BY ANALYTIC HIERARCHY PROCESS BASED 0-1 INTEGER PROGRAMMING by Yılmaz GÖKŞEN, Hakan AŞAN, Onur DOĞAN, Mustafa ÜNLÜ, Osman PALA

“…The coefficients of the variables in the objective function of the assignment model constitute potential contributions of employees. …”
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Anti-inflammatory actions of ripasudil ameliorate experimental autoimmune uveoretinitis in the acute phase by Tomohito Sato, Masaru Takeuchi, Kozo Harimoto, Hideaki Someya, Masataka Ito, Yoshiaki Nishio

“…Introduction Rho-associated protein kinases (ROCKs) are a key regulator of T cell function, influencing a wide range of processes from activation to differentiation. …”
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Licensing Approach Applicable to Land Facilities Supporting Nuclear-Powered Submarines by Douglas Baroni, S Borsoi, M Mattar Neto, P Oliveira, M Maturana

“…Due to the innovation of this type of installation in Brazil, there is no specific regulation for its licensing, constituting a unique situation for both the Brazilian Navy (applicant) and the National Nuclear Energy Commission - CNEN (Brazilian Nuclear Licensing Agency, which, in the near future, will have its function incorporated into the National Nuclear Safety Authority, ANSN). …”
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Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb Lymphedema by Sara Bernasconi, Giovanni Maria Oriolo, Giovanni Farina, Andrea Aliverti, Antonella Lomauro

“…A wearable device, constituted by two boards with 2 IMUs, connected by a flexible flat cable, was designed and developed for placement across targeted joints. …”
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Terrestrial Spatial Distribution and Summer Abundance of Antarctic Fur Seals (Arctocephalus gazella) Near Palmer Station, Antarctica, From Drone Surveys by Gregory D. Larsen, Megan A. Cimino, Julian Dale, Ari S. Friedlaender, Marissa A. Goerke, David W. Johnston

“…Using repeat animal counts and photogrammetric data products, we modeled fur seal abundance at survey sites over the period of observation, modeled habitat suitability based on fine‐scale topographic habitat characteristics, and estimated abundance across terrestrial habitats near Palmer Station as a function of these products. High habitat suitability was most associated with low‐slope and low‐elevation inshore terrain and with relatively dry, sun‐exposed, and wind‐sheltered locations, and estimated peak abundance occurred on March 11 (day 71) of 2020. …”
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Neuroimaging Insights into the Public Health Burden of Neuropsychiatric Disorders: A Systematic Review of Electroencephalography-Based Cognitive Biomarkers by Evgenia Gkintoni, Apostolos Vantarakis, Philippos Gourzis

“…<i>Background and Objectives</i>: Neuropsychiatric disorders, including schizophrenia, bipolar disorder, and major depression, constitute a leading global public health challenge due to their high prevalence, chronicity, and profound cognitive and functional impact. …”
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Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway. by Hui H Zhang, Jingxiang Huang, Katrin Düvel, Bernard Boback, Shulin Wu, Rachel M Squillace, Chin-Lee Wu, Brendan D Manning

“…One direct substrate that is inhibited by Akt-mediated phosphorylation is the tuberous sclerosis complex 2 (TSC2) protein, which associates with TSC1 and acts as a critical negative regulator of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1). Loss of function of the TSC1-TSC2 complex results in constitutive mTORC1 signaling and, through mTORC1-dependent feedback mechanisms and loss of mTORC2 activity, leads to a concomitant block of Akt signaling to its other downstream targets.…”
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Predictors of macular pigment and contrast threshold in Spanish healthy normolipemic subjects (45-65 years) with habitual food intake. by Begoña Olmedilla-Alonso, Elena Rodríguez-Rodríguez, Beatriz Beltrán-de-Miguel, Rocío Estévez-Santiago, Milagros Sánchez-Prieto

“…The HDL-cholesterol would also act indirectly on the CT improving the visual function.…”
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Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer. by Anju Singh, Vikas Misra, Rajesh K Thimmulappa, Hannah Lee, Stephen Ames, Mohammad O Hoque, James G Herman, Stephen B Baylin, David Sidransky, Edward Gabrielson, Malcolm V Brock, Shyam Biswal

“…<h4>Conclusions</h4>This is the first study to our knowledge to demonstrate that biallelic inactivation of KEAP1 is a frequent genetic alteration in NSCLC. Loss of KEAP1 function leading to constitutive activation of NRF2-mediated gene expression in cancer suggests that tumor cells manipulate the NRF2 pathway for their survival against chemotherapeutic agents.…”
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Cultural Resilience from Sacred to Secular: Ritual Spatial Construction and Changes to the Tujia Hand-Waving Sacrifice in the Wuling Corridor, China by Tianyi Min, Tong Zhang

“…Overall, this study reveals a unique path for non-literate ethnic groups to achieve the intergenerational transmission of cultural memory through the collusion of material symbols and physical art practices, as well as the possibility of embedding the hand-waving sacrifice ritual into contemporary spatial practice through symbolic translation and functional extension in the context of social function inheritance and variation. …”
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Efficiency of neutralization of electric charges on the surface of dielectric nonwoven fabric of two dual and triode electrode systems by B. Yahiaoui, A. Messaoudene, A. Melahi, A. Rahmani, B. Bendahmane, L. Dascalescu

“…The static charges are often considered annoying and constitute one of the main sources of hazards. Thus, their neutralization is more than necessary. …”
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Esophageal cancer related gene-4 is a choroid plexus-derived injury response gene: evidence for a biphasic response in early and late brain injury. by Sonia Podvin, Ana-Maria Gonzalez, Miles C Miller, Xitong Dang, Hannah Botfield, John E Donahue, Arwa Kurabi, Matthew Boissaud-Cooke, Ryan Rossi, Wendy E Leadbeater, Conrad E Johanson, Raul Coimbra, Edward G Stopa, Brian P Eliceiri, Andrew Baird

“…Accordingly, augurin would play a constitutive inhibitory function in normal CNS while down regulation of Ecrg4 gene expression in injury, like in cancer, dysinhibits proliferation.…”
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The linc009 negatively regulates cell apoptosis in turbot (Scophthalmus maximus L.) during bacterial challenge by Beibei Wang, Xiaocheng Zhu, Xinghua Zhuang, Xiaoli Liu, Zhongyi Wang, Ning Yang, Chao Li

“…This study provided valuable insights into the function and regulatory mechanism of lncRNAs in teleost.…”
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Unlocking Apoptotic Pathways: Overcoming Tumor Resistance in CAR‐T‐Cell Therapy by Zhanna Zhang, Manqi Su, Panruo Jiang, Xiaoxia Wang, Xiangmin Tong, Gongqiang Wu

“…We assess the impact of the tumor microenvironment (TME) on CAR‐T cell function and propose dual‐targeting CAR‐T cells to simultaneously address both myeloid‐derived suppressor cells (MDSCs) and tumor cells. …”
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Análisis del comportamiento del material de la arteria aorta ascendente para su modelación// Behavior analysis of the ascending aorta artery material for modeling by Diana Otero‐Martínez, Luis L. Otero‐Pereiro, Vladimir González‐Fernandez

“…<br /><br /><strong>Key words:</strong> arterial tissue engineering, constitutive modelling, elasticity, aortic wall, characteristics of arteries…”
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Perturbation based privacy preservation and classification using Jaya Algorithm and Dragonfly Inspired Algorithm by Dipanwita Sen, Bhupati Bhusan Mishra, Prasant Kumar Pattnaik

“…The patients’ health details constitute private personal information. They should not be disclosed. …”
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