Global sensitivity analysis and uncertainty quantification for a mathematical model of dry anaerobic digestion in plug-flow reactors by Daniele Bernardo Panaro, Andrea Trucchia, Vincenzo Luongo, Maria Rosaria Mattei, Luigi Frunzo

“…Sensitivity analysis and uncertainty quantification constitute essential tools in the field of biological systems modeling. …”
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Human pulmonary microvascular endothelial cells respond to DAMPs from injured renal tubular cells by Sean E. DeWolf, Alana A. Hawkes, Sunil M. Kurian, Diana E. Gorial, Mark L. Hepokoski, Stephanie S. Almeida, Isabella R. Posner, Dianne B. McKay

“…This paper adds to our understanding of PRR expression and function in pulmonary HMVECs and provides a foundation for future work aimed at developing therapeutic strategies to prevent lung injury following AKI.…”
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Synthesis, Characterization, and Structural Studies of Some Homo- and Heteroleptic Cu(I) Complexes Bearing 6,6′-Bis(phenylethynyl)-2,2′-Bipyridine Ligand by Rayya A. Al-Balushi, Md. Serajul Haque Faizi, Md. Mushtaque, Idris J. Al-Busaidi, Muhammad S. Khan

“…Coordination-driven Cu(I) complexes constitute an interesting class of materials with rich opto-electronic properties and diverse applications. …”
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Effects of habitat characteristics in an anthropized landscape on the spatial behavior and abundance of a common chameleon (Chamaeleo chamaeleon) population by M. A. Farfán, J. Duarte, D. Romero, L. Colorado‐Pedrero, P. García‐Quevedo, R. Arroyo‐Morales, F. Díaz‐Ruiz

“…We used the Favorability Function (FF) to assess how the observations (i.e., presence/absence) of common chameleons were affected by distance from the highway, habitat characteristics, and food availability. …”
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Characterization of an unusual SARS-CoV-2 main protease natural variant exhibiting resistance to nirmatrelvir and ensitrelvir by Dipendra Bhandari, Oksana Gerlits, Stephen Keable, Leighton Coates, Annie Aniana, Rodolfo Ghirlando, Nashaat T. Nashed, Andrey Kovalevsky, John M. Louis

“…Abstract We investigate the effects of two naturally selected substitution and deletion (Δ) mutations, constituting part of the substrate binding subsites S2 and S4, on the structure, function, and inhibition of SARS CoV-2 main protease. …”
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Modeling the service life of temporary airfield operational surfaces under multi-pass aircraft trafficking by R.P. Kinser, T.W. Rushing, A.R. Cisko, Mark E. Barkey, P.G. Allison, J.B. Jordon

“…Finite element studies were conducted for an EAF surfacing system brickwork configuration subjected to aircraft strut loads over varying California Bearing Ratio (CBR) subgrades to calibrate a transfer function to full-scale trafficking experiments. The proposed framework is then used to predict the rate of subgrade deformation for additional lay patterns, which successfully ranked the performance of each relative to full-scale trafficking experiments. …”
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Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion by Marizela Delic, Alexandra B. Graf, Gunda Koellensperger, Christina Haberhauer-Troyer, Stephan Hann, Diethard Mattanovich, Brigitte Gasser

“…Yap1 is needed for the detoxification of reactive oxygen species (ROS) caused by increased oxidative protein folding. Constitutive co-overexpression of PpYAP1 leads to increased levels of secreted recombinant protein, while a lowered Yap1 function leads to accumulation of ROS and strong flocculation. …”
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<i>IGFBP5</i> Promotes Atherosclerosis in APOE^−/− Mice Through Phenotypic Transformation of VSMCs by Aoqi Xiang, Hua Guan, Peihong Su, Lusha Zhang, Xiaochang Chen, Qi Yu

“…Atherosclerosis constitutes a pathological process underlying cardiovascular diseases. …”
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Numerical Simulation of Electromagnetic Nondestructive Testing Technology for Elasto–Plastic Deformation of Ferromagnetic Materials Based on Magneto–Mechanical Coupling Effect by Xiangyi Hu, Xiaoqiang Wang, Haichao Cai, Xiaokang Yang, Sanfei Pan, Yafeng Yang, Hao Tan, Jianhua Zhang

“…This paper also investigates the effect of elasto–plastic deformation on the transient magnetic flux signal, a quantitative hyperbolic tangent model between B<i>z</i>_pp (peak–peak value of the normal component of magnetic flux signal) and elastic stress, and the exponential function relationship between B<i>z</i>_pp and plastic deformation is established. …”
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Orthosteric STING inhibition elucidates molecular correction of SAVI STING by Tao Xie, Max Ruzanov, David Critton, Leidy Merselis, Joseph Naglich, John S. Sack, Ping Zhang, Chunshan Xie, Jeffrey Tredup, Laurel B. Stine, Cameron Messier, David L. Hope, Janet Caceres-Cortes, Luciano Mueller, Alaric J. Dyckman, John A. Newitt, Asmita Choudhury, Stephen C. Wilson

“…Questions persist about the molecular properties needed to distinguish between a STING activator and inhibitor, particularly within SAVI disease, a monogenic autoinflammatory disease that renders STING constitutively active, and how different conformations correlate to function. …”
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TNIK-driven regulation of ERK5 transcriptional activity in endothelial cells by Venkata Subrahmanya Kumar Samanthapudi, Sivareddy Kotla, Nhat-Tu Le

“…Extracellular signal-regulated kinase 5 (ERK5) is essential for cardiovascular development and endothelial cell (EC) function. Activation of ERK5 through MEK5-mediated phosphorylation at threonine 218 and tyrosine 220 (T218/Y220) drives the transcriptional activation of myocyte enhancer factor-2 (MEF2), promoting the expression of KLF2 and KLF4—key transcription factors that maintain vascular homeostasis. …”
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Nutrigenomic and Nutritional Analyses Reveal the Effects of Pelleted Feeds on Asian Seabass (Lates calcarifer). by Si Yan Ngoh, Daniel Tan, Xueyan Shen, Purushothaman Kathiresan, Junhui Jiang, Woei Chang Liew, Natascha May Thevasagayam, Hsiao Yuen Kwan, Jolly M Saju, Sridatta R S Prakki, Chin Heng Goh, Hong Ching Wong, Tai Teck Chan, Miklós Mézes, László Orbán

“…Significant enrichment of genes with growth-related function tallied with the morphological data measured. …”
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DISCUSSIONS REGARDING A POSSIBLE GOVERNMENT GUARDIANSHIP CONTROL OVER ADMINISTRATIVE ACTS by Constantin Claudiu ULARIU

“…The Government, as an emblematic and fundamental exponent of executive power within the framework of the rule of law, alongside the President of Romania, constitutes a determinant structure of representative democracy. …”
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Telecom Fraud Recognition Based on Large Language Model Neuron Selection by Lanlan Jiang, Cheng Zhang, Xingguo Qin, Ya Zhou, Guanglun Huang, Hui Li, Jun Li

“…In the realm of natural language processing (NLP), text classification constitutes a task of paramount significance for large language models (LLMs). …”
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Late Byzantine spiritual guidance in the letters of the metropolitan of Chalcedon to the nun Eulogia by Alevtina Matveeva

“…The spiritual letters themselves serve as instruments of influence as their function extends beyond communication and maintaining social connections. …”
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Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targets. by Eumorphia G Konstantakou, Athanassios D Velentzas, Athanasios K Anagnostopoulos, Zoi I Litou, Ourania A Konstandi, Aikaterini F Giannopoulou, Ema Anastasiadou, Gerassimos E Voutsinas, George Th Tsangaris, Dimitrios J Stravopodis

“…Our advanced melanoma-specific catalogue proved to contain 6,681 unique proteins, which likely constitute the hitherto largest single cell-line-derived proteomic collection of the disease. …”
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Informal caregiving following stroke: a qualitative exploration of carer self-identification, care-related language and support experiences by Richard Brown, Audrey Bowen, Bethany Harcourt

“…The study took place from September 2021 to April 2024.Participants 18 adults (aged 18 years and above) who had provided care or support to a friend or family member after a stroke that occurred at least 1 year prior to participation completed the study.Results Five main themes were developed: (1) adopting and adjusting to the care role, (2) accessibility of support, (3) perceptions of support, (4) acceptability of care-related language and terminology and (5) function of care-related language and terminology. …”
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INNOVATIVE ASPECTS OF OPEN INGUINAL HERNIA SURGERY: REDUCING COMPLICATIONS AND PREVENTING RECURRENCES by К. Рахманов, О. Хужамов, С. Давлатов, Б. Хамдамов, С. Янченко, Н. Абдуллаєва, З. Джалілова

“… Inguinal hernias constitute a significant portion of surgical pathology and remain among the most common reasons for seeking surgical consultation. …”
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Altered lower leg muscle activation patterns in patients with cerebral palsy during cycling on an ergometer by Alves-Pinto A, Blumenstein T, Turova V, Lampe R

“…Ana Alves-Pinto,1,* Tobias Blumenstein,1,* Varvara Turova,1 Ren&amp;eacute;e Lampe1,2 1Research Unit of the Buhl-Strohmaier Foundation for Cerebral Palsy and Paediatric Neuroorthopaedics, Orthopaedic Department, Klinikum rechts der Isar, 2Markus W&amp;uuml;rth Professorship, Technical University of&amp;nbsp;Munich, Munich, Germany *These authors contributed equally to&amp;nbsp;this work Objective: Cycling on a recumbent ergometer constitutes one of the most popular rehabilitation exercises in cerebral palsy (CP). …”
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Degeneration modulates retinal response to transient exogenous oxidative injury. by Michal Lederman, Shira Hagbi-Levi, Michelle Grunin, Alexey Obolensky, Eduard Berenshtein, Eyal Banin, Mordechai Chevion, Itay Chowers

“…<h4>Methods</h4>Retinal oxidative injury was induced in degenerating retinas (rd10) and in control mice (WT) by intravitreal injections of paraquat (PQ). Retinal function and structure was evaluated by electroretinogram (ERG) and histology, respectively. …”
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