Suggested Topics within your search.
Suggested Topics within your search.
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1501
STAT signaling pathways in immune cells and their associated mechanisms in cancer pathogenesis
Published 2024-05-01“…Methods: In the current study, we review recent studies on the contribution of individual STAT proteins to cytokine signaling, development, and activity of diverse immune cells that constitute the whole immune system and help its performance against endogenous or exogenous agents with a particular focus on meaningful STAT factor in each of innate and adaptive immune cells’ subsets to clarify their function in favor of the tumor or against it. …”
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1502
Efficacy of Routine Fecal Microbiota Transplantation for Treatment of Recurrent Clostridium difficile Infection: A Retrospective Cohort Study
Published 2019-01-01“…Patients with recurrent Clostridium difficile infections (CDIs) constitute an increasing treatment problem. Fecal microbiota transplantation (FMT) has shown promising results of treating recurrent CDI, where treatment with antibiotics fails repeatedly. …”
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1503
Networked Language Communities: From Constructed Languages to Natural Languages
Published 2022-12-01“…The situation with the functioning of regional languages will change either with the revitalization of old language communities, or with the formation of new language communities in which the language can function as a real means of communication and will gain a new lease on life. …”
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1504
A Multi-Objective PSO-GWO Approach for Smart Grid Reconfiguration with Renewable Energy and Electric Vehicles
Published 2025-04-01“…Distribution network reconfiguration emerges as a pivotal strategy to mitigate power losses, facilitate the seamless assimilation of renewable generation, and regulate the charging and discharging dynamics of EVs, thereby constituting a critical endeavor in modern electrical engineering. …”
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1505
Interaction between two timing microRNAs controls trichome distribution in Arabidopsis.
Published 2014-04-01“…The miR156-targeted squamosa promoter binding protein like (SPL) transcription factors function as an endogenous age cue in regulating plant phase transition and phase-dependent morphogenesis, but the control of SPL output remains poorly understood. …”
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1506
Mesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes.
Published 2017-02-01“…To date, mutations within the coding region and translocations around the SOX9 gene both constitute the majority of genetic lesions underpinning human campomelic dysplasia (CD). …”
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1507
Reconstructing Equatorial Electron Flux Measurements From Low‐Earth‐Orbit: A Conjunction Based Framework
Published 2025-03-01“…For each conjunction, we fit the equatorial pitch angle distribution (PAD) parameterized by the function JD=C⋅sinNα. The resulting conjunction data set contains the POES electron flux measurements, L and magnetic local time coordinates, geomagnetic activity Auroral Electrojet index, and C and N coefficients from the PAD fit for each conjunction. …”
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1508
IL-33 is produced by mast cells and regulates IgE-dependent inflammation.
Published 2010-08-01“…Recombinant IL-33 has been shown to enhance Th2-associated immune responses and potently increase mast cell proliferation and cytokine production. While IL-33 is constitutively expressed in endothelial and epithelial cells, where it may function as a transcriptional regulator, cellular sources of IL-33 and its role in inflammation remain unclear.…”
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1509
Cell type differences in human cytomegalovirus transcription and epigenetic regulation with insights into major immediate-early enhancer-promoter control.
Published 2025-08-01“…Here we report unexpected differences in transcription and epigenetic control in late-stage HCMV infection of human differentiated NTera2 neural lineage cells (D-NT2) compared to fibroblasts, using integrated functional genomic approaches (PRO-Seq, RNA-Seq, DNA fragmentation factor-ChIP Seq, rapid viral protein degradation, and promoter mutation and function assays). …”
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1510
Beyond coincidence: a case series on the clinical course of coinciding cluster headache and short-lasting unilateral neuralgiform headache attacks
Published 2025-06-01“…Conclusion:. This study constitutes the most extensive description to date of individuals diagnosed with both cluster headache and SUNHA. …”
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1511
SEXUALLY TRANSMITTED INFECTIONS AS THE PROBLEM OF DEMOGRAPHIC DEVELOPMENT OF SIBERIAN FEDERAL DISTRICT
Published 2013-05-01“…In the article the negative medico-demographic and social and economic value of consequences of sexually transmitted infections is indicated that causes their inclusion in the list of socially significant diseases which constitute danger to people around. It is specified that complications of sexually transmitted infections lead to formation of congenital diseases, break reproductive function of younger generation, negatively affect birth rate indicators, worsen a demographic situation, aggravating depopulation processes in Russia and its territorial units. …”
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1512
Modifications of the maximum expiratory flow in bronchial asthma treatment using Intal and Ketotifeno.
Published 2003-12-01“…<strong>Introduction</strong>: The studies of the lung function are essential for the diagnosis, classification and treatment of the Bronchial Asthma and inside them the mensuration of the flow maximum expiratory (FEM) it provides a quantitative value of the obstruction of the air roads. …”
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1513
Optimization of biosensor based on nitride-photonic crystal operating in visible range for Glucose detection
Published 2025-06-01“…Furthermore, the resonant wavelength, the quality factor (Q) and the sensitivity (S) of the proposed biosensor were evaluated as a function of the number of periods and glucose concentration. …”
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1514
Topology Optimization of Constrained Layer Damping on Plates Using Method of Moving Asymptote (MMA) Approach
Published 2011-01-01“…Meantime, the modal damping ratio of the plate is assigned as the objective function in the topology optimization approach. The sensitivity of modal damping ratio to design variable is further derived and Method of Moving Asymptote (MMA) is adopted to search the optimized topologies of constrained layer damping layout on the plate. …”
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1515
Ultrastructural changes in the common carotid artery in terms of age and gender-related in Rat model
Published 2025-02-01“…The circulatory system serves various functions in the body such as nourishing organs and tissues, oxygenating and eliminating toxic substances. …”
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1516
In-depth and high-throughput spatial proteomics for whole-tissue slice profiling by deep learning-facilitated sparse sampling strategy
Published 2025-03-01“…Therefore, spatially resolved gene expression profiling is crucial for determining the function and phenotypes of these cells. While genome mutations and transcriptome alterations act as drivers of diseases, the proteins that they encode regulate essentially all biological functions and constitute the majority of biomarkers and drug targets for disease diagnostics and treatment. …”
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1517
A novel BLK-induced tumor model
Published 2017-06-01“…BLK is known to be functionally involved in B-cell receptor signaling and B-cell development. …”
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1518
Impact of wearable-assisted walking on sarcopenia and body composition in older adults
Published 2025-07-01“…Abstract Background Physical inactivity constitutes a global public health challenge, particularly among older adults. …”
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1519
Water quality awareness and barriers to safe water provisioning in informal communities: A case study from Ndola, Zambia
Published 2014-12-01“…The apparent paradox between awareness of risks to water and implementing protection of that water source is a function of the complex suite of socially manifested attitudes, habits and behaviours when it comes to water protection and treatment, which is exacerbated by vulnerable community and family structures and entrenched poverty. …”
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1520
The influence of soil carbonates on highbush blueberry plants in the conditions of the Kabardino-Balkarian Republic
Published 2024-04-01“…Acidic conditions are necessary due to the unique structure of the root system: highbush blueberries are completely devoid of root hairs; their function is performed by a colony of fungi, which constitutes mycorrhiza in symbiosis with the plant. …”
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