Systems-level analysis of NalD mutation, a recurrent driver of rapid drug resistance in acute Pseudomonas aeruginosa infection. by Jinyuan Yan, Henri Estanbouli, Chen Liao, Wook Kim, Jonathan M Monk, Rayees Rahman, Mini Kamboj, Bernhard O Palsson, Weigang Qiu, Joao B Xavier

“…Transcriptomics analysis confirmed the primary mechanism of NalD action-a loss-of-function mutation that caused constitutive overexpression of the MexAB-OprM efflux system-which lead to aztreonam resistance but, surprisingly, had no fitness cost in the absence of the antibiotic. …”
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A Pandemic of Possibilities: The Spread of Potentiality-Seeking Organisations under Conditions of the COVID-19 Lockdown by Andersen Niels Åkerstrøm, Carli Giacomo, Stenner Paul, Tagliaventi Maria Rita

“…They pursue opportunities stemming from learning to ‘expect the unexpected’, while still calling on function systems to stabilize expectations.…”
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Kształtowanie Belek Sprężonych przez Wyrównywanie Skrajnych Naprężne by A. Brandt

“…In Sec. 8, it is shown that for beams of considerable span, where the dominating role is played by shape in the unloaded state. own weight, it is reasonable to determine the several problems are solved, showing the determination of the shape of the beams in cases where functions sought for are the beam. height a(x) and the ordinate of the prestressing force; the beam height a(x), with constant position of the prestressing force (Sec. 5); the variable width of the beam b(3e), the ordinate of the force constituting a given function y(x) (Sec. 6); the beam width b(x) and the ordinate of the prestressing force y(x), (Sec. 7). …”
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The ESCRT-0 component HRS is required for HIV-1 Vpu-mediated BST-2/tetherin down-regulation. by Katy Janvier, Annegret Pelchen-Matthews, Jean-Baptiste Renaud, Marina Caillet, Mark Marsh, Clarisse Berlioz-Torrent

“…We demonstrate that Vpu-mediated BST-2/tetherin down-modulation and degradation require HRS (ESCRT-0) function and that knock down of HRS increases cellular levels of BST-2/tetherin and restricts virus release. …”
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Early enteral nutrition in surgical treatment of an acute complicated pancreatitis by V. P. Andriushchenko, D. V. Andriushchenko, V. V. Kunovskyi, Yu. S. Lysiuk

“…EEN in the patients, suffering an acute complicated pancreatitis constitutes an effective component of surgical treatment in preoperative and postoperative periods.…”
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A New Soil-Water Characteristic Curve Model for Unsaturated Loess Based on Wetting-Induced Pore Deformation by Yuwei Zhang, Zhanping Song, Xiaolin Weng, Yongli Xie

“…The new model includes 6 parameters, which could be confirmed by laboratory tests. The pore volume function (PVF) was described by the WIPD. The shift factor ξ1i and the compression factor ξ2i were introduced into the model. …”
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THE DEATH OF ART IN ADORNO'S THEORY OF ANTINOMOUS NATURE OF THE WORKS OF ART by Rūta Marija Marija Vabalaitė

“…The concept of death is to mean that the work is and is not itself, as it is the function of its other-the historical reality. The condition of non-identity lies in the negative relations among the individual moments of a work and a work as a whole. …”
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The role of nucleosome positioning in the evolution of gene regulation. by Alexander M Tsankov, Dawn Anne Thompson, Amanda Socha, Aviv Regev, Oliver J Rando

“…Chromatin organization plays a major role in gene regulation and can affect the function and evolution of new transcriptional programs. …”
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Calibration of empirical penetration models using large deformation explicit finite element simulations of rapid penetration in clay by Boules N. Morkos, Rachel White, Mehdi Omidvar, Magued Iskander

“…A modified Tresca constitutive model is implemented in ABAQUS software to capture key features of clay behavior under high strain rate (HSR) loading. …”
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The Role of Microglia and Macrophages in CNS Homeostasis, Autoimmunity, and Cancer by Jie Yin, Katherine L. Valin, Michael L. Dixon, Jianmei W. Leavenworth

“…In this overview, we summarize the current knowledge regarding the highly diverse and complex function of microglia and macrophages during CNS autoimmunity—multiple sclerosis and cancer—malignant glioma. …”
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Metody Wariacyjne w Teorii Sztywno-Plastycznych Powłok Cylindrycznych by P.P. Mosołow, W.P. Miasnikow

“…It is shown (Sec. 1) that in the general three-dimentional formulation of the problem for arbitrary rigid-plastic media, the limiting Joad is determined by the perfectly plastic part of the function of dissipation of the medium. Subsequently it is shown (Sec. 2-5) that the classical theory of (perfect) shells based on the assumption of disregarding the shear strain in the material of the shell constitutes an asymptotically exact theory of the problems of stretching and bending at a shell thickness approaching zero. …”
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Optimally controlled heating of solid particles in a fluidised bed with a dispersive flow of the solid by Poświata Artur, Szwast Zbigniew

“…Results of this discussion constitute a novelty in comparison to information presented in current literature.…”
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Healthcare Operation Improvement Based on Simulation of Cooperative Resource Preservation Nets for None-Consumable Resources by Soraia Oueida, Yehia Kotb, Seifedine Kadry, Sorin Ionescu

“…Healthcare systems are growing very fast, especially emergency departments (EDs) which constitute the major bottleneck of these complex concurrent systems. …”
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Numerical investigation of nonlinear deformations with contact interaction by A.I. Abdrakhmanova, L.U. Sultanov

“…The elastic deformation potential function has been used to obtain the constitutive relations. …”
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Effect of communication in talent management practice on non-high potential outcomes by Maman Alimansyah, Yoshi Takahashi

“…The results successfully explained the exchange resource function, an unexplored area in the literature of SET. …”
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Peculiarities of course of the urolithiasis disease in patients with a solitary kidney and concomitant diabetes mellitus type II by D. I. Кuprin, А. I. Boyko, N. О. Saidakova, А. О. Gubar

“…There was established, that even in adequately corrected hyperglycemia in the patients, having a solitary kidney, the risk for unfavorable course of urolithiasis disease and diabetes mellitus type II is higher, than in patients, having both functioning kidneys. The majority of patients, having a solitary kidney, owe the lowered velocity indices of glomerular filtration and glomerular hyperfiltration, proteinuria and arterial hypertension, what, even in presence of diabetes mellitus with the middle severity course, constitutes a high risk for rapid lowering of renal function. …”
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Cerebral Vasospasm Pharmacological Treatment: An Update by Ioannis Siasios, Eftychia Z. Kapsalaki, Kostas N. Fountas

“…Aneurysmal subarachnoid hemorrhage- (aSAH-) associated vasospasm constitutes a clinicopathological entity, in which reversible vasculopathy, impaired autoregulatory function, and hypovolemia take place, and lead to the reduction of cerebral perfusion and finally ischemia. …”
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The RhoGDIβ-Rac1-CARD9 Signaling Module Mediates Islet β-Cell Dysfunction Under Chronic Hyperglycemia by Anjaneyulu Kowluru, Jie-Mei Wang

“…Small (monomeric) GTP-binding proteins (smgs; Cdc42 and Rac1) play requisite roles in islet beta cell function, including glucose-stimulated insulin secretion. …”
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Developmental time course and effects of immunostressors that alter hormone-responsive behavior on microglia in the peripubertal and adult female mouse brain. by Mary K Holder, Jeffrey D Blaustein

“…In female mice, the experience of being shipped from the breeder facility or a single injection of the bacterial endotoxin, lipopolysaccharide (LPS), during pubertal development alters the behavioral response to estradiol in adulthood as demonstrated by perturbations of estradiol's effects on sexual behavior, cognitive function, as well as its anxiolytic and anti-depressive properties. …”
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Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Requirements by Michelle M Pluhator, Alan BR Thomson, Richard N Fedorak

“…Intake less than the required levels can cause impaired function, disease and death. Every essential nutrient has a unique range of tissue concentration and intake necessary for proper physiological and biochemical functioning. …”
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