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1301
Essential gene acquisition destabilizes plasmid inheritance.
Published 2021-07-01“…Plasmids carrying an essential host function are recognized as permanent residents in their host. …”
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1302
Phonotactic constraints in cognitive phonology
Published 2009-06-01“…Consequently, phonotactic constraints, which pertain to meaningless units, would constitute no independent knowledge base either. Also, languages are learned in function of their actual use, and negative phonotactic constraints, characterizing something that cannot be said, must be excluded on these grounds as well from a speaker’s grammar since it would be difficult to learn them in the absence of positive data (Taylor 2002). …”
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1303
Notched implements made of scapulae (Bruszczewo-type tools)-A problem solved? Discovering cereal- and legume-threshing techniques in Early Bronze Age Europe through traceological a...
Published 2024-01-01“…The studies presented in this paper constitute the first scientific attempt to interpret the manner whereby notched implements made of scapulae were made and used. …”
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1304
RBM4-mediated intron excision of Hsf1 induces BDNF for cerebellar foliation
Published 2024-12-01“…Abstract Brain-derived neurotrophic factor (BDNF) plays important roles in brain development and neural function. Constitutive knockout of the splicing regulator RBM4 reduces BDNF expression in the developing brain and causes cerebellar hypoplasia, an autism-like feature. …”
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1305
Current concepts in managing fractures of metacarpal and phalangess
Published 2011-01-01“…Fractures of the metacarpal and phalanges constitute 10% of all fractures. No where in the body, the form and function are so closely related to each other than in hand. …”
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1306
Direitos Humanos, Ciências Sociais e Poder Judiciário / Human Rights, Social Sciences and Judiciary
Published 2011-09-01“…The rights are neither a reflection of past historical reproduction cycles nor the deduction of the human rights of political constitutions. They are a specific type of discourse with practical and social function.…”
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1307
Divergent receiver responses to components of multimodal signals in two foot-flagging frog species.
Published 2013-01-01“…To understand signal evolution and function in multimodal signal design it is critical to test receiver responses to unimodal signal components versus multimodal composite signals. …”
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1308
Experimental Study of Strain Rockburst considering Temperature Effect: Status-of-the-Art and Prospect
Published 2021-01-01“…According to the occurrence state of country rock for deep high-temperature and stress state in the whole process during excavation, six development directions for high-temperature strain rockburst simulation tests were proposed: (1) constructing the damage constitutive models of high-temperature rocks according to linear energy dissipation law; (2) developing the true triaxial rockburst simulation testing system accomplishing the function of “real-time high temperature + unloading + dynamic disturbance”; (3) considering the true triaxial rockburst simulation test after microwave irradiation; (4) developing the real-time high-temperature rockburst simulation testing device for large-size specimens and internal unloading; (5) focusing on the energy actuating mechanism for deep high-temperature rock failure via rockburst simulation tests; and (6) implementing the three-dimensional rockburst simulation test on the basis of deep in situ coring.…”
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1309
Role of Pseudoexons and Pseudointrons in Human Cancer
Published 2013-01-01“…In healthy individuals, alternative and constitutive splicing processes function with a high degree of precision and fidelity in order to ensure the correct working of this machinery. …”
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1310
Conservation’s green illusion: Nitrogen thresholds as critical determinants of extinction risk in specialist herbivores
Published 2025-10-01“…Sub-threshold habitats can function as ecological traps, silently undermining translocation, reproduction, and survival even in structurally intact forests. …”
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1311
„Россия поднимается с колен” четверть века спустя: медиалингвистический анализ политической мифологемы...
Published 2025-06-01“…The mythologeme – as a verbal carrier of the myth, a complex type of a sign with the function of a concept and figurative content – serves as a symbolic encoding of the world and consolidation of society. …”
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1312
Referenece and its effect on the textuality in (farewell sermon)
Published 2022-10-01“…The study starts with an introduction to linguistics and textuality and its function. It deals with a short introduction of textuality in the Arabic rhetoric because Arabic rhetoric constitutes an important part in the modern linguistics both theoretically and practically. …”
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1313
Le développement de l’enseignement clinique à Paris et la création de l’école clinique interne de l’hôpital de la Charité
Published 2011-12-01“…The superiority gained by that hospital due to the novelty of the teaching that was provided in it explained why, when health schools were created by the National Convention on 14 Frimaire An III (December 4, 1794), it was the place that was chosen to establish the first school of clinical medicine that would be provided with premises most specially adapted to its function. Because of the budgetary contingencies associated with the political situation, the yard happened to be interrupted several times, but was eventually carried through. …”
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1314
THE METHOD OF OPTIMIZATION OF THE SET OF TECHNICAL FACILITIES TO PROVIDE AVIATION SAFETY AND SECURITY
Published 2016-12-01“…The actuality of problem of optimizing the set of technical facilities to provide aviation safety and security is determined by the necessity to develop aviation security provision system taking into account the analysis of threats while ensuring balance between expenses on security support and possible damage from the act of unlawful interference.The offered method of optimization consists of two main stages: determination of the optimal total expenses and determination of the optimal set of technical facilities.The first stage is devoted to analysing the threats and solving the task of optimization of total expenditures on the technical aids set used to ensure aviation safety and security which means searching for the minimum of total expenses goal function. These expenses constitute a sum of expenses spent on technical aids set and damage from the act of unlawful interference.The second methodological stage deals with setting the task of parameters synthesis. …”
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1315
Fantastic Realia: Some Lexical Correspondences (Russian-Romanian)
Published 2021-09-01“…Moreover, another present-day function was assigned to folkloric, mythological elements (the mythemes) through their animated metamorphosis into the realm of video games, already being annotated, listed online. …”
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1316
Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity.
Published 2024-12-01“…By mutating acetylation sites on Ydj1's J-domain to either abolish or mimic constitutive acetylation, we observed that preventing acetylation had no noticeable phenotypic impact, whereas acetyl-mimic mutants exhibited various defects indicative of impaired Ydj1 function. …”
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1317
Multi-Scale Agent-Based Multiple Myeloma Cancer Modeling and the Related Study of the Balance between Osteoclasts and Osteoblasts.
Published 2015-01-01“…Furthermore, the drug synergism analysis function of the model revealed that restoring the balance between OBs and OCs can significantly increase the efficacy of drugs against tumor cells.…”
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1318
Peripheries of Narration and Spatial Poetics in Wilkie Collins’s The Moonstone
Published 2022-12-01“…Spatial poetics in the novel functions in a way in which despite the myriad of settings that constitute the story, narrative discourse privileges some places while putting the others into the peripheries. …”
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1319
In Vitro Murine Hematopoiesis Supported by Signaling from a Splenic Stromal Cell Line
Published 2018-01-01“…To analyse the hematopoietic support function of 5G3, specific signaling pathway inhibitors were tested for the ability to regulate cell production in vitro in cocultures of stroma overlaid with bone marrow-derived hematopoietic stem/progenitor cells. …”
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1320
Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.
Published 2014-01-01“…Here we have identified multiple sites of CPC autophosphorylation on yeast Sli15 that are located within its central microtubule-binding domain and examined the functional significance of their phosphorylation by Ipl1 through mutation of these sites, either to non-phosphorylatable alanine (sli15-20A) or to acidic residues to mimic constitutive phosphorylation (sli15-20D). …”
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