A patient-centered qualitative evaluation of meaningful change on the NSAA and PUL in Duchenne Muscular Dystrophy by Aviva Gillman, Teofil Ciobanu, Louise Barrett, Evan W. Davies, Alexander P. Murphy, Alex Johnson, Jessica Mills, Phoebe Heinrich, Krystian Przydzial, Bethany Ewens, Gerrit Vandenberg, Stefan Cano, Anna Mayhew

“…There is limited published qualitative evidence on what constitutes a meaningful change on either instrument. …”
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Double-Layer Optimization Mechanism for Multi-Area OPF Considering Valve-Point Loading Effect by Jizhong Zhu, Cong Zeng, Yun Liu, Xuancong Xu

“…In terms of the multi-area optimal power flow (OPF) problem, the optimized objectives are always a fuel cost function expressed by a second-order polynomial. However, the valve-point loading effect, whose cost curve is a transcendental function formed by the superposition of the sine and polynomial function, will make the objective function non-convex and non-differentiable. …”
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Formation of a dynamic knowledge base of fuzzy inference systems for estimating changing in time objects by A. Kostikova, N. Skiter

“…In the same way as the dynamic membership function constitutes a fuzzy surface in “the degree of membership-parameter-time space”, a linguistic variable composed of dynamic terms, represents a graphically broken surface with n - vertices according to the number of terms.…”
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Astrocyte-Synapse Structural Plasticity by Yann Bernardinelli, Dominique Muller, Irina Nikonenko

“…Glial cells constitute an important part of this environment and participate in several aspects of synaptic functions. …”
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Vimar Is a Novel Regulator of Mitochondrial Fission through Miro. by Lianggong Ding, Ye Lei, Yanping Han, Yuhong Li, Xunming Ji, Lei Liu

“…In support of this hypothesis, a loss-of-function (LOF) vimar mutant rescued mitochondrial enlargement induced by a gain-of-function (GOF) Miro transgene; whereas a GOF vimar transgene enhanced Miro function. …”
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Examining the normative results of the Arab Spring on the legal status of religious minorities; Case study of Egypt by mohammad yosefzadeh, mohammad jalali

“…Secondly, the centralization of religious affairs within the state, weakness in executive and functional procedures, lack of easy and effective access to justice, justification of discrimination and violence, establishing an interpretation based on identity of the Egyptian and the Islamic identities, among others, have been influential in the failure to achieve the constitutional goals and the demands of religious minorities for equality in rights and autonomy in the religious domain.Conclusion: This article, by a pathological analyzing the obstacles to the realization and exercise of the rights and freedoms of religious minorities, makes the following suggestions: Firstly, the Egyptian government must be committed to upholding the philosophy and implications of the constitution not only in theory but also in practice; Secondly, in order to observe the elements of citizenship rights, the necessary and appropriate infrastructures should be designed and implemented, and efforts should be made to assess and enhance them in cooperation with non-governmental organizations; Thirdly, the content of the educational system’s curriculum should be revised and reformed to promote tolerance and altruism; And finally, the right to self-determination, along with all its necessary conditions, should be recognized and respected for religious minorities…”
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FEATURES OF THE EARLY MORPHOGENESIS OF THE CENTRAL NERVOUS SYSTEM by Т. Хмара, О. Цигикало, І. Заморський, Т. Паньків, Т. Комшук, О. Сметанюк

“…The work is carried out within the framework of the initiative research work of the Department of Histology, Cytology and Embryology of Institution of  the Bukovinian State Medical University "Structural and functional peculiarities of tissues and organs in ontogenesis, regularities of variant, constitutional, sex-, age-related and comparative human morphology". …”
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On the covariance estimation of the simple processes by Mohammadreza Mahmoudi

“…Since autocovariance function is an important tool in both theoretical and practical time series analysis, this paper deals with the estimation of the autocovariance function for simple processes. …”
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Thyroid axis alterations in childhood obesity by Bogda Skowrońska, Elżbieta Niechciał, Anna M. Gertig

“…In recent years researchers have become increasingly interested in the particular relation between the function of the thyroid gland and the body mass in the population of obese children. …”
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Financial and legal aspects of innovation clusters by A. S. Kirpa

“…The study contributes to the formation of approaches to the value, effectiveness and targeting of financial and legal incentives that affect the development of innovation clusters.At the same time, the authors proceeded from an interdisciplinary approach, since the problem of the legal status of innovation clusters inevitably affects the subject of regulation of various branches of law and has both constitutional and legal, financial, legal, civil, administrative and other aspects.For the most correct and uniform understanding of the elements of the social relations under consideration, the authors pay attention to the categorical and conceptual apparatus, which reflects intersectoral relations and the dual legal nature of the studied relations arising from the functioning of innovative clusters. …”
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Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide im... by Sentaro Kaita, Yoshikazu Morishita, Kenta Kobayashi, Hiroshi Nomura

“…Histamine H3 receptors constitutively inhibit the synthesis and release of histamine and other neurotransmitters. …”
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Experimental autoimmune encephalomyelitis causes skeletal muscle dysfunction in mice by Julian Boesch, Pamela Ramseier, Sarah Tisserand, Eliane Pierrel, Giuseppe Locatelli, Serge Summermatter

“…As we conduct force measurements by direct transcutaneous muscle stimulation in anesthetized animals, our setup allows for the repeated evaluation of muscle function, and in the absence of primary fatigue or reduced nerve input which constitute important confounding factors in MS. …”
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Real-world therapeutic performance of pirfenidone for connective tissue disease-associated interstitial lung diseases by Xueting Yuan, Chen Yu, Shengyun Liu, Qiang Shu, Xinwang Duan, Lin Tang, Liying Peng, Shuang Zhou, Chanyuan Wu, Jiuliang Zhao, Dong Xu, Lan Song, Hui Huang, Mengtao Li, Yanhong Wang, Qian Wang, Xiaofeng Zeng

“…A linear mixed effects model was employed to evaluate the effectiveness of PFD in alleviating lung function changes. Differences in response to PFD were analyzed based on CTD subtype, imaging classification, and pattern of pulmonary function at baseline. …”
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Mitochondrial haplogroups modify the risk of developing hypertrophic cardiomyopathy in a Danish population. by Christian M Hagen, Frederik H Aidt, Paula L Hedley, Morten K Jensen, Ole Havndrup, Jørgen K Kanters, Johanna C Moolman-Smook, Severin O Larsen, Henning Bundgaard, Michael Christiansen

“…Thus, constitutive differences in mitochondrial function may influence the occurrence and clinical presentation of HCM. …”
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The Heme Oxygenase/Biliverdin Reductase System and Its Genetic Variants in Physiology and Diseases by Cesare Mancuso

“…Regarding <i>BVR</i>, the reported loss-of-function mutations increase the risk of green jaundice. …”
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ENSURING STATE SOVEREIGNTY AS A GUARANTEE OF THE COUNTRY'S ECONOMIC DEVELOPMENT by Iryna Drobush, Liudmila Kornuta, Mykola Ukrainets

“…Ensuring Ukraine's state sovereignty as an independent, democratic, social and legal state is a complex, multifaceted and multi-level process that includes such key areas of activity as: guaranteeing the stability of the Ukrainian state; developing all elements of Ukraine's legal system; improving the efficiency of the organisation and functioning of the entire system of state power, not just individual branches and/or bodies of state power; strengthening the economic, cultural, social, political, environmental and security potential of the state; positioning Ukraine on the international and domestic arena as an active player capable of solving complex problems at the national and global levels and capable of predictable and reliable international co-operation; strengthening the democratic nature of the Ukrainian state and guaranteeing the foundations of Ukraine's constitutional order. …”
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Interpretation of Local Flux Measurements in Subcritical Systems and Reactivity Determination by S. Dulla, P. Ravetto

“…The determination of the subcriticality level constitutes an important issue in the assessment of the accelerator-driven system technology. …”
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Ambient air pollution undermines chemosensory sensitivity – a global perspective by Anna Oleszkiewicz, Andrea Pozzer, Jonathan Williams, Thomas Hummel

“…Abstract This study offers insights into the complex relationship between chemical species constituting air pollution and chemosensory function. …”
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ROLE OF GENETIC VARIABILITY IN METABOLIC PATHWAYS ON CISPLATIN-INDUCED KIDNEY INJURY IN HEAD AND NECK CANCER PATIENTS by Ericka Francislaine Dias Costa, Ana Maria Castro Ferreira, Marilda Mazzali, Gustavo Jacob Lourenço, Carmen Silvia Passos Lima

“…Results: Patients with the GSTT1 present and ERCC1 c.354CT or TT isolated genotypes presented a decline in kidney function of 4.94% and 8.94%, respectively. A decline of 17.67% in renal function post-CDDP treatment was observed in patients with the GSTT1 present combined with TP53 c.215CC genotype. …”
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WASIAT RENUNGAN MASA-PENGALAMAN BARU KARYA HAMZANWADI: PRAGMATISME PUISI LAMA PADA ERA MODERN MENURUT CULTURAL STUDIES by Khirjan Nahdi, Herman Wijaya, Muh Taufiq, Dukha Yunitasari

“…Research data ws collected trough transcription tehnique because the text of Renungan Masa-Pengalaman Baru is a lingual symbol (forms) to understand meaning and function. Analysis and data interpretation used phenomenology approach. …”
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