Evolution of tandem repeats in putative circumsporozoite protein to enhance its function: A recent and exclusive event in Plasmodium vivax in India by Manoswini Dash, Veena Pande, Aparup Das, Abhinav Sinha

“…This concept can be applied to identify loci with functional and evolutionary significance. Putative circumsporozoite protein in Plasmodium vivax (PvpuCSP) identified following the molecular hitchhiking model, holds evolutionary significance. …”
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Integrated and Functional Genomics Analysis Validates the Relevance of the Nuclear Variant ErbB380kDa in Prostate Cancer Progression. by Mahmoud El Maassarani, Alice Barbarin, Gaëlle Fromont, Ouafae Kaissi, Margot Lebbe, Brigitte Vannier, Ahmed Moussa, Paule Séité

“…Detecting ErbB380kDa could thus constitute a useful marker of prognosis and response to therapy.…”
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Regulation of immune responses by a tumor necrosis factor in pearl oysters: insights from PmTNF gene expression and function by Wu Yifan, Liang Bidan, Liang Haiying

“…Analysis of PmTNF mRNA expression via real-time PCR reveals its constitutive expression in all the examined tissues, with the highest expression in the gills. …”
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Characterizing the Endophytic Microbiome and Microbial Functional Assemblages Associated with Fengtang Plum (<i>Prunus salicina</i> Lindl.) Development and Resistance by Jiqing Lei, Yinna Shi, Hong Li, Rui Wang

“…This study elucidates microbial community succession patterns during Fengtang plum development; notably, functional predictions were inferred from 16S/ITS sequencing data rather than direct metagenomic or metatranscriptomic analyses, thus limiting mechanistic interpretations, though future work integrating multi-omics approaches would strengthen functional insights.…”
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Function of HP1BP3 as a linker histone is regulated by linker histone chaperones, NPM1 and TAF-I by Miharu Hisaoka, Tetsuro Komatsu, Takuma Hashimoto, Jianhuang Lin, Yasuyuki Ohkawa, Mitsuru Okuwaki

“…Abstract Background Linker histones constitute a class of proteins that are responsible for the formation of higher-order chromatin structures. …”
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Plasma AGE and Oxidation Products, Renal Function, and Preeclampsia in Pregnant Women with Type 1 Diabetes: A Prospective Observational Study by Clare B. Kelly, Harsha Karanchi, Jeremy Y. Yu, Misti J. Leyva, Alicia J. Jenkins, Alison J. Nankervis, Kristian F. Hanssen, Satish K. Garg, James A. Scardo, Samar M. Hammad, Christopher E. Aston, Paul J. Beisswenger, Timothy J. Lyons

“…We aimed to determine whether plasma advanced glycation end products or oxidation products (AGE/oxidation-P) predict altered renal function and/or preeclampsia (PE) in pregnant women with type 1 diabetes. …”
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Broad-line AGNs at 3.5 < z < 6: The Black Hole Mass Function and a Connection with Little Red Dots by Anthony J. Taylor, Steven L. Finkelstein, Dale D. Kocevski, Junehyoung Jeon, Volker Bromm, Ricardo O. Amorín, Pablo Arrabal Haro, Bren E. Backhaus, Micaela B. Bagley, Eduardo Banados, Rachana Bhatawdekar, Madisyn Brooks, Antonello Calabrò, Óscar A. Chávez Ortiz, Yingjie Cheng, Nikko J. Cleri, Justin W. Cole, Kelcey Davis, Mark Dickinson, Callum Donnan, James S. Dunlop, Richard S. Ellis, Vital Fernández, Adriano Fontana, Seiji Fujimoto, Mauro Giavalisco, Andrea Grazian, Jingsong Guo, Nimish P. Hathi, Benne W. Holwerda, Michaela Hirschmann, Kohei Inayoshi, Jeyhan S. Kartaltepe, Yana Khusanova, Anton M. Koekemoer, Vasily Kokorev, Rebecca L. Larson, Gene C. K. Leung, Ray A. Lucas, Derek J. McLeod, Lorenzo Napolitano, Masafusa Onoue, Fabio Pacucci, Casey Papovich, Pablo G. Pérez-González, Nor Pirzkal, Rachel S. Somerville, Jonathan R. Trump, Stephen M. Wilkins, L. Y. Aaron Yung, Haowen Zhang

“…Finally, we compute the BLAGN UV luminosity function and find agreement with JWST-detected BLAGN samples from recent works, finding that BLAGN hosts constitute ≲10% of the total observed UV luminosity at all but the brightest luminosities.…”
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Analysis of thyroid function and structure and serum metabolomics in pregnant rats exposed to airborne contaminants: Combined perchlorate, thiocyanate, and nitrate exposure by Chenchen Wang, Xiaohui Xu, Jiangling Yuan, Ran An, Aierken Taxitiemuer, Yan Zhang, Tao Luo, Jing Zhou, Chang Wang, Ling Zhang, Shunhua Wu

“…We investigated the effects of inhalation of these pollutants on thyroid function and structure and serum metabolomics in pregnant rats. …”
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Pasteurization and the Potential Anti-Obesity Function of Fermented Beverages: A Significant Increase in Nitrogen-Containing Aromatic Heterocyclic Compound Content by Xiurong Wu, Ting Wang, Xiangzhen Nie, Yanglin Wu, Jinghan Wang, Haoming Wang, Rui Dai, Ronghan Liu, Yingying Cui, Miaoting Su, Yang Qiu, Xiantao Yan

“…However, few studies have investigated the effects of pasteurization on the active components and potential functions of PBF water extract fermentation broth. …”
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Real-time changes in brain activity during sacral neuromodulation for overactive bladder: evidence from functional near-infrared spectroscopy by Runtian Luo, Runtian Luo, Limin Liao, Limin Liao

“…ObjectiveThe mechanisms underlying overactive bladder (OAB) and the role of sacral neuromodulation (SNM) in its treatment are not fully understood. In this study, functional near-infrared spectroscopy (fNIRS) was used to identify changes in brain activity during SNM in patients with OAB who responded to therapy.MethodsWe employed a prospective trial method and idiopathic OAB patients selected for SNM treatment at our center were assigned to the experimental group and healthy adults matched by gender and age constituted the healthy control (HC) group. …”
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GPD2 inhibition impairs coagulation function via ROS/NF-κB/P2Y12 pathway by Jiajie Chen, Guifeng Xu, Zhipeng Xie, Shaoxia Xie, Wenwei Luo, Shilong Zhong, Weihua Lai

“…As antiplatelet therapy constitutes the cornerstone of CHD management, ticagrelor has been universally endorsed as a first-line agent in major clinical guidelines. …”
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Achieving Defense by Means of Forensic Science During the Criminal Proceedings in Romania by Delia Magherescu

“…The function of defense during the criminal proceedings in Romania is the result of traditional separation of the three procedural functions of accusation, judgement and defense. …”
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Yeast as a model system to study metabolic impact of selenium compounds by Enrique Herrero, Ralf Erik Wellinger

“…Inorganic Se forms such as selenate or selenite (the two more abundant forms in nature) can be toxic in Saccharomyces cerevisiae cells, which constitute an adequate model to study such toxicity at the molecular level and the functions participating in protection against Se compounds. …”
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A novel CARD11 heterozygous missense variant in a CADINS patient by Randa S. AlYafie, PhD, Mehdi Adeli, MD, Dinesh Velayutham, PhD, Salim Bougarn, PhD, Manar Ata, MSc, Fatima Al-Ali, MRes, Evonne Chin-Smith, PhD, Bradly M. Bauman, PhD, Andrew L. Snow, PhD, Bertrand Boisson, PhD, Nico Marr, PhD, Nicholas van Panhuys, PhD, Andrea Guennoun, PhD, Puthen Veettil Jithesh, PhD

“…Expression of CARD11 variant–stimulated constitutive NF-κB activity in T-cell lines demonstrated both loss-of-function and dominant-negative activity. …”
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Russia: property and state. The history of post-Soviet law enforcement (Part I) by Alexander V. Butakov

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Biopsychological and pathophysiological features of Cold-Heat subgroup of Sasang typology with Sasang Digestive Function Inventory, Sasang Personality Questionnaire and Body Mass I... by Jeongyun Lee, Sang Yun Han, Minwoo Hwang, Nayoung Bae, Han Chae

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Cytotoxic and Bactericidal Effect of Silver Nanoparticles Obtained by Green Synthesis Method Using Annona muricata Aqueous Extract and Functionalized with 5-Fluorouracil by María del Carmen Sánchez-Navarro, Claudio Adrian Ruiz-Torres, Nereyda Niño-Martínez, Roberto Sánchez-Sánchez, Gabriel Alejandro Martínez-Castañón, I. DeAlba-Montero, Facundo Ruiz

“…As a simple and economical synthesis methodology, this work presents a method to synthesize silver nanoparticles (AgNPs) using Annona muricata aqueous extract and functionalized with 5-fluorouracil (5-FU). The processes of reduction, nucleation, and functionalization of the nanoparticles were analyzed by UV-Vis absorption spectroscopy, and it was found that they are the function of the contact time of the metal ions with the extract. …”
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Characteristics of Soil Nematode Communities in Pure <i>Populus hopeiensis</i> Forests in the Loess Hilly Region and Their Responses to Precipitation by Yani Hu, Jiahao Shi, Fangfang Qiang, Changhai Liu, Ning Ai

“…Precipitation indirectly regulated nematode functionality by modifying soil physicochemical properties and microbial activity. (5) Ecological function analysis revealed bacterial-dominated organic matter decomposition (Nematode Channel Ratio, <i>NCR</i> > 0.75) in the Changcheng and Baibao sites, contrasting with fungal channel predominance (<i>NCR</i> < 0.75) in Jinfoping. …”
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Genome-Wide Analysis of PAPS1-Dependent Polyadenylation Identifies Novel Roles for Functionally Specialized Poly(A) Polymerases in Arabidopsis thaliana. by Christian Kappel, Gerda Trost, Hjördis Czesnick, Anna Ramming, Benjamin Kolbe, Son Lang Vi, Cláudia Bispo, Jörg D Becker, Cornelia de Moor, Michael Lenhard

“…As shown by their different mutant phenotypes, these three isoforms are functionally specialized, with PAPS1 modifying organ growth and suppressing a constitutive immune response. …”
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Evaluating Cognitive Function and Brain Activity Patterns via Blood Oxygen Level-Dependent Transformer in N-Back Working Memory Tasks by Zhenming Zhang, Yaojing Chen, Aidong Men, Zhuqing Jiang

“…(1) Background: Working memory, which involves temporary storage, information processing, and regulating attention resources, is a fundamental cognitive process and constitutes a significant component of neuroscience research. …”
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