Candidate Phyla Radiation (CPR) bacteria from hyperalkaline ecosystems provide novel insight into their symbiotic lifestyle and ecological implications by Yu He, Shiyan Zhuo, Meng Li, Jie Pan, Yongguang Jiang, Yidan Hu, Robert A. Sanford, Qin Lin, Weimin Sun, Na Wei, Shuming Peng, Zhou Jiang, Shuyi Li, Yongzhe Li, Yiran Dong, Liang Shi

“…Results In the highly alkaline serpentinite-like ecosystem (pH = 10.9–12.4), metagenomic analyses of the water and sediment samples revealed that CPR bacteria constituted 1.93–34.8% of the microbial communities. …”
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Individual Pharmacotherapy Management (IPM-II) for Patient and Drug Safety in Polypharmacy via Clinical Electronic Health Record Is Associated with Significant Fall Prevention by Ursula Wolf, Luise Drewas, Hassan Ghadir, Christian Bauer, Lars Becherer, Karl-Stefan Delank, Rüdiger Neef

“…Conclusion: The results indicate medication risks constitute a major iatrogenic cause of falls in this population and support the use of EHR-based IPM in standard care for the prevention of falls in the elderly and for patient and drug safety. …”
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Risks of parasitic helminth disease outbreaks and influence of physico-chemical factors in flood prone areas of Yaoundé, Cameroon by Noura Efietngab Atembeh, Jean Patrick Molu, Jeanne Valerie Emvoutou Maboulou, Boris Fominyam, Rodrigue Nanfack Dongmo, Gabriel Bertrand Zambo, Emilie Tchinda Tiecheu, Jeannette Tombi, Lucia Nkengazong, Serge Hubert Zebaze Togouet, Jean Louis Essame Oyono

“…Conclusion: Flood areas constitute a potential risk zone for the maintenance and spread of human helminthiases. …”
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Enfermedad periodontal en embarazadas atendidas en la Clínica Estomatológica Manuel Angulo Farrán by Yunaydis Tamayo Avila

“…Dental care is essential in early pregnancy to prevent functional damage that may be permanent psychological from the periodontal disease leading to tooth loss.     …”
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Hypoxia-inducible factors: details create a picture. Part I. HIF-1 by G. A. Ignatenko, N. N. Bondarenko, S. V. Tumanova, T. S. Ignatenko, A. A. Kaluga, Ya. S. Valigun

“…The review presents a comparative analysis of scientific data on the structural and functional characteristics of subunits (HIF-1α and HIF-1β) of hypoxia-inducible transcription factor-1 (HIF-1). …”
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Overexpression of soybean SGF14a enhanced tolerance of transgenic tobacco plants to aluminum stress by Yang Zhili, Guo Chuanlong, Liu Lei, Wu Konghuan, Wang Lin, Li Kunzhi, Zhao Yan, Chen Limei

“…A lot of 14-3-3 gene family members are isolated in different plants. 14-3-3 proteins regulate various physiological activities and functions by interacting with phosphorylated or non-phosphorylated target proteins in plants. …”
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Ellenreformáció, felvilágosodás, állami erőkoncentráció-optimalizálás? Heinrich Kajetan Blümegen grófjának bevonása az erdélyi vallásügyek főfelügyeletébe 1763–64-ben... by Kálmán Árpád KOVÁCS

“…The House, Court, and State Archives has functioned as the most important depository for court-related subjects since Kaunitz’s founding of the Council of State. …”
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1.7 MV Tandem Accelerator Beam Tuning Optimization by JIANG Ran, LI Ailing, CUI Baoqun, TANG Bing, CHEN Haonan, WANG Yunfeng

“…This interface empowered efficient upper-level control and real-time monitoring functions, thereby significantly bolstering the usability and practicality of the system. …”
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ASCT2 inhibits HIV-1 infectivity by promoting the incorporation of a gp160/ASCT2 complex into virions by Luciana Morellatto Ruggieri, Eri Miyagi, Sandra Kao, Hideki Saito, Aymé Drake Figueredo, Haruki Kitamura, María I. Colombo, Klaus Strebel

“…Our results show that ASCT2 is constitutively expressed in CD4+ T cells and macrophages, but its expression can be upregulated by the antiviral cytokine IFNα. …”
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Sustainable Development Clauses in the International Law of the Sea by A. N. Vylegzhanin, A. M. Korzhenyak

“…The research involves methods of legal construction, legal modeling, analysis and synthesis, systematic, struc­tural-functional, formal-logical, formal-legal, histori­cal and chronological methods.  …”
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Inpatient compliance with levothyroxine timing: a clinical audit of administration practices and patient knowledge by Nadia Ibrahim, Bilal Kahara, Nehmiea Melese, Hafiz Nasir, Kamal Naser

“…Hence, guidelines recommend that it is taken on an empty stomach, at least 30 min before food, caffeine-containing drinks and some medication.1–3 On busy wards with medication and meal rounds possibly functioning independently, sticking to this standard is challenging, and made more so by the knowledge gap. …”
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أثر الدين في التوجهات الجيوبوليتيكية للولايات المتحدة الأمريكية تجاه إسرائيل by عيسى السيد عيسى دسوقي, حسن قطب حسن قطب

“…It focuses on the role of evangelical and Christian Zionist movements in shaping U.S. foreign policy, highlighting how religion functions both as an ideological force and a tool for political mobilization within executive and legislative institutions. …”
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STYLISTIC MEANS OF IMPLEMENTING THE IDEA OF THE WORLD’S IRIDESCENCE IN PH.K. DICK’S “UBIK” IN THE CONTEXT OF TRANSLATION TRANSFORMATIONS by Svitlana F. Aleksenko, Larysa I. Taranenko

“…The method of stylistic analysis was applied to interpret stylistic phenomena inherent in the novel in relation to their contribution to the studied idea as those were found functioning in the relevant textu- al microcontexts and enhancing the aforementioned semantic dominants. …”
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Integrative Analysis Provides Insights into Genes Encoding LEA_5 Domain-Containing Proteins in Tigernut (<i>Cyperus esculentus</i> L.) by Zhi Zou, Xiaowen Fu, Xiaoping Yi, Chunqiang Li, Jiaquan Huang, Yongguo Zhao

“…LEA_5 domain-containing proteins constitute a small family of late embryogenesis-abundant proteins that are essential for seed desiccation tolerance and dormancy. …”
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Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells by Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu

“…We investigated the biological functions of JAG2 in immune evasion using in vitro co‐culture systems, flow cytometry, tumor‐bearing mouse models, and PDTOs. …”
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BdNRT2A and BdNRT3.2 Are the Major Components of the High‐Affinity Nitrate Transport System in Brachypodium distachyon by Laure C. David, Mathilde Grégoire, Patrick Berquin, Anne Marmagne, Marion Dalmais, Abdelhafid Bendahmane, Tony J. Miller, Anne Krapp, Françoise Daniel‐Vedele, Thomas Girin, Sylvie Ferrario‐Méry

“…An effective nitrate transport in the heterologous expression system Xenopus oocytes required the coexpression of BdNRT2A and BdNRT3.2 that characterizes two‐component system of the HATS. Functional interaction between BdNRT2A‐GFP and BdNRT3.2‐RFP fusion proteins was observed at the plasma membrane in Arabidopsis protoplasts in transient expression experiments with BdNRT3.2 being necessary for the plasma membrane localization of BdNRT2A. …”
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IQUB mutation induces radial spoke 1 deficiency causing asthenozoospermia with normal sperm morphology in humans and mice by Tingwenyi Hu, Xiangrong Tang, Tiechao Ruan, Shunhua Long, Guicen Liu, Jing Ma, Xueqi Li, Ruoxuan Zhang, Guoning Huang, Ying Shen, Tingting Lin

“…To date, many components of RSs and their functions in human sperm flagella remain unclear. Methods We recruited a cohort of 323 infertile males with ASZ between August 2019 and June 2024. …”
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Methylome analysis of FTLD patients with TDP-43 pathology identifies epigenetic signatures specific to pathological subtypes by Cristina T. Vicente, Tejasvi Niranjan, Elise Coopman, Júlia Faura, Sara Alidadiani, Claudia Schrauwen, Billie J. Matchett, Bavo Heeman, Marleen Van den Broeck, Wouter De Coster, Thuy Nguyen, Julie S. Lau, Saurabh Baheti, Tim de Pooter, Peter De Rijk, Mojca Strazisar, Matt Baker, Mariely DeJesus-Hernandez, NiCole A. Finch, Cyril Pottier, Marka van Blitterswijk, Yan Asmann, Melissa E. Murray, Leonard Petrucelli, Andrew King, Claire Troakes, Safa Al-Sarraj, Robert A. Rissman, Annie Hiniker, Margaret Flanagan, Bret M. Evers, Charles L. White, Carlos Cruchaga, Rudolph Castellani, Jeroen G.J. van Rooij, Merel O. Mol, Harro Seelaar, John C. van Swieten, Björn Oskarsson, Robert Ross Reichard, Aivi T. Nguyen, Keith A. Josephs, Ronald C. Petersen, Nilüfer Ertekin-Taner, Bradley F. Boeve, Neill R. Graff-Radford, Sarah Weckhuysen, Dennis W. Dickson, Rosa Rademakers

“…Abstract Background In the last decade, the importance of DNA methylation in the functioning of the central nervous system has been highlighted through associations between methylation changes and differential expression of key genes involved in aging and neurodegenerative diseases. …”
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Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer by Tiankai Xu, Chu Chu, Shuyu Xue, Tongchao Jiang, Ying Wang, Wen Xia, Huanxin Lin

“…Abstract Background Drug resistance constitutes one of the principal causes of poor prognosis in breast cancer patients. …”
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Architecture and the Time of Space by Deborah Hauptman

“…And, subsequently, a practical desire to understand the conditions that constituted experience, and thus perception, sensation and mind. …”
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