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2241
Evolutionary dynamics of predicted G-quadruplexes in human and other great apes
Published 2025-06-01“…Analyzing inter-species whole-genome alignments, we identify pG4s shared across apes (approximately one-third of all pG4s) and thousands of species-specific pG4s. pG4s accumulate and diverge at rates consistent with divergence times between species, following molecular clock. pG4s shared across apes are enriched and hypomethylated at regulatory regions—enhancers, promoters, UTRs, and origins of replication—suggesting their conserved formation and functions. Species-specific pG4s (constituting 11–27% of all pG4s) are located in regulatory regions, potentially contributing to adaptations, and in repeats, likely driving genome expansions. …”
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2242
Clinical Outcomes of Allograft Superior Capsular Reconstruction for Irreparable Posterosuperior Rotator Cuff Tears in Patients Aged 65 and Older: A Retrospective Study
Published 2025-04-01“…Results indicated a significant postoperative improvement in VAS score (5.1–1.6, P < 0.001) and functional outcomes. Postoperative MRI demonstrated intact grafts in 46 patients, constituting a survival rate of 90.2%. …”
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2243
Endocannabinoid System and Synaptic Plasticity: Implications for Emotional Responses
Published 2007-01-01“…In this paper, we will focus on the functional relevance of endocannabinoid-mediated plasticity within the framework of emotional responses. …”
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2244
Heterologous expression of a chloride transporter gene AoCLCf from Avicennia officinalis enhances salt tolerance of Arabidopsis plants
Published 2025-05-01“…Spectrofluorimetric assays using liposomes embedded with recombinant AoCLCf protein showed that it functions as a chloride channel. These findings underscore the pivotal role of AoCLCf in improving salt stress tolerance through the maintenance of cellular ion homeostasis.…”
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2245
A Structural Study of the Tales of the Moment of Attention of Sufi Sheikhs in Persian Sufi Poems
Published 2024-12-01“…The predominant theme of these narratives is the emphasis on the doctrine of functional unity, leading to the concepts of trust in God and acceptance of divine will, aligning with the Sufi theological and epistemological approach…”
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2246
Composition, Influencing Factors, and Effects on Host Nutrient Metabolism of Fungi in Gastrointestinal Tract of Monogastric Animals
Published 2025-03-01“…Intestinal fungi, collectively referred to as mycobiota, constitute a small (0.01–2%) but crucial component of the overall intestinal microbiota. …”
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2247
Metagenomics Insights into the Role of Microbial Communities in Mycotoxin Accumulation During Maize Ripening and Storage
Published 2025-04-01“…To investigate mycotoxin contamination, microbial diversity, and functional profiles in maize across distinct geographic regions, this study analyzed samples from Xuanwei, Fuyuan, and Zhanyi. …”
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2248
Luminal Cerebrovascular Proteomics
Published 2025-08-01“…These cells exhibit strong apicobasal polarity, with distinct luminal and abluminal membrane compositions that crucially mediate compartmentalized functions of the vasculature. Existing transcriptomic and proteomic profiling techniques often lack the spatial resolution to discriminate between these membrane compartments, limiting insights into their distinct molecular compositions and functions. …”
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2249
Prognosis of cholangiocarcinoma patients based on multiple patterns of programmed cell death, integrated analysis of the immune microenvironment and drug sensitivity
Published 2025-05-01“…The score’s prognostic value was assessed through survival analysis, ROC curves, and functional annotation.ResultsWe identified 111 differentially expressed PCD-related genes, including NCK2, BNIP3 and BIK, that constituted PCD-associated Risk Score and correlated with prognosis of CHOL. …”
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2250
Phytochemicals That Influence Gut Microbiota as Prophylactics and for the Treatment of Obesity and Inflammatory Diseases
Published 2018-01-01“…Gut microbiota (GM) plays several crucial roles in host physiology and influences several relevant functions. In more than one respect, it can be said that you “feed your microbiota and are fed by it.” …”
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2251
Evolutionary insights into Interleukin-12 family targets across 405 species
Published 2025-05-01“…These findings establish an evolutionary framework explaining functional conservation/divergence in IL-12 signaling components. …”
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2252
Transcriptomic Analysis of Venom Secretion in <i>Achelura yunnanensis</i>: Lipid Metabolism, Redox Reactions, and Structural Adaptations
Published 2025-06-01“…Conversely, genes linked to non-venom-related functions, such as extracellular matrix organization and epidermal development, were downregulated in LDET, indicating resource reallocation toward venom production. …”
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2253
Investigating Women's Preferences in the Public Spaces of Gated Communities - A Case Study of Atisaz Residential Complex
Published 2024-09-01“…Considering that women constitute half of the population of any society and are responsible for a significant portion of family functions, taking into account their preferences and needs in shaping residential environments can contribute to their physical, mental health, and overall quality of life. …”
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2254
Vulnerability of benthic trait diversity across the Mediterranean Sea following mass mortality events
Published 2025-02-01“…By analyzing changes in ten ecological traits across 389 benthic species—constituting an extensive compendium of Mediterranean ecological traits to date—we identified 228 functional entities (FEs), defined as groups of species sharing the same trait values. …”
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2255
Grammatical Multifunction via Causativity: Evidence from Morpheme Po55 in the Yanzhou (Jiande) Dialect
Published 2025-06-01“…The morpheme po55 in the Yanzhou (Jiande) dialect functions as either a verb of giving or an object marker (Cao 2017). …”
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2256
Is the university an authoritarian institution? A theoretical exploration with Lacan, Fromm, and Rancière
Published 2025-07-01“…Rather than labeling the university as an inherently authoritarian institution, the article argues that it constitutes a social field in which authoritarian tendencies may emerge and take effect—often in subtle and structurally embedded forms. …”
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2257
Co-speech gestures influence the magnitude and stability of articulatory movements: evidence for coupling-based enhancement
Published 2025-01-01“…Speech and gesture synergies therefore constitute an independent variable to consider when modeling the effects of prosodic prominence on articulatory patterns. …”
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2258
Computational intelligence for disease diagnosis: an approach based on neutrosophic logic
Published 2025-05-01“…It is concluded that the neutrosophic approach constitutes an effective and flexible alternative to traditional binary classification models, providing a robust computational framework for medical decision-making under uncertainty. …”
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2259
The HCF101 protein is an important component of the cytosolic iron-sulfur synthesis pathway in Toxoplasma gondii.
Published 2025-02-01“…Several key cellular functions depend on proteins harboring an iron-sulfur (Fe-S) cofactor. …”
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2260
The Warmian Dietine in the 16th–18th Centuries
Published 2009-12-01“…They were, in fact, the officials constituting the core of the estate representation of the Bishopric. …”
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