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1721
Formation of CSE-YAP complex drives FOXD3-mediated transition of neurotoxic astrocytes in Parkinson’s disease
Published 2024-12-01“…Astrocytes, constituting the predominant glial cells in the brain, undergo significant morphological and functional transformations amidst the progression of Parkinson’s disease (PD). …”
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1722
High temperature stress-strain data for SAE 5120 steel under various strain ratesDataverse
Published 2025-08-01“…The processed data, averaged from raw tests, were then used to characterize austenite flow stress as a function of strain rate and temperature using the incremental approach. …”
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1723
Physiological and Transcriptomic Analysis of a Sepal Mutant in <i>Phalaenopsis</i>
Published 2025-05-01“…MADS-box transcription factors have undergone in-depth investigations regarding their function in regulating the development of plant floral organs. …”
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1724
Patients with Coronary Artery Disease Have Lower Levels of Antibody to Heat-Stressed Fibroblast Derived Proteins, versus Normal Subjects
Published 2021-01-01“…Inhibition of cellular stress may provide a novel clinical approach regarding the diagnosis and treatment of CAD. Fibroblasts constitute 60-70% of cardiac cells and have a crucial role in cardiovascular function. …”
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1725
Clinical spectrum and uncommon features of McCune-Albright syndrome in children: a cohort study from a National Referral Center
Published 2025-02-01“…IntroductionMcCune-Albright syndrome (MAS) is a rare disease caused by somatic gain-of-function variants in the GNAS gene that lead to constitutive activation of the G protein alpha subunit (Gsα). …”
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1726
Postzygotic mosaicism in SMC1A and the first reported case of a female with Cornelia de Lange syndrome
Published 2025-07-01“…Molecular dynamics simulations suggest that this mutation disrupts the elbow domain of SMC1A, potentially impairing cohesin function. Further delineation of phenotypes and genotypes associated with PZM variants in SMC1A reveals that, similar to constitutive variants, mosaic mutations are predominantly missense and distributed throughout the gene. …”
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1727
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1728
A Trade‐Off Between Leaf Carbon Economics and Plant Size Among Mangrove Species in Dongzhaigang, China
Published 2024-11-01“…ABSTRACT Plant size is closely linked to its leaf trait characteristics, which are essential for determining its form and function. These relationships constitute a fundamental component of the global spectrum of plant diversity. …”
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1729
Distribution and Neurochemical Characterization of Dorsal Root Ganglia (DRG) Neurons Containing Phoenixin (PNX) and Supplying the Porcine Urinary Bladder
Published 2025-03-01“…The present study reveals the extensive expression of PNX in the DRGs supplying to the urinary bladder, indicating an important regulatory role of this neuropeptide in the control of physiological function(s) of this organ.…”
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1730
Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations
Published 2025-03-01“…Here, we investigate the role of hemodynamic forces and the biophysical microenvironment in the pathophysiology of vascular malformations (VMs), and we identify hemodynamic shear stress and defective endothelial cell mechanotransduction as key regulators of lesion progression. We found that constitutive PI3K activation impaired flow-mediated endothelial cell alignment and barrier function. …”
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1731
Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27kip1 pathway
Published 2025-05-01“…In this study, we investigated the function of COX-2 in the osteogenic differentiation of BMSCs. …”
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1732
Good outcomes of bipolar radial head arthroplasty for comminuted radial head fractures: a cohort study of 64 patients with an average 5.2-year follow-up
Published 2025-06-01“…This study aimed to assess the functional and radiological outcomes of elbow injuries involving comminuted radial head fractures treated with bipolar radial head arthroplasty. …”
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1733
Extraction of Optimal Measurements for Drowsy Driving Detection considering Driver Fingerprinting Differences
Published 2021-01-01“…Secondly, the genetic algorithms were used to optimize fitness functions to obtain measured IDBCPs. Finally, we selected measurements calculated by IDBCPs that can distinguish drowsy driving to constitute individual drivers’ optimal drowsiness-detection measurement set. …”
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1734
Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of MYCN
Published 2024-09-01“…Conclusion The HSF1‐MYCN axis constitutes a transcription‐dependent regulatory mechanism that may function as both a prognostic indicator and a promising therapeutic target in liver cancer. …”
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1735
Inteligência biológica versus inteligência artificial: uma abordagem crítica Biologic intelligence versus artificial intelligence: a critical approach
Published 1995-09-01“…In the present paper it is stressed that brain/mind complex constitutes a monolithic system that functions with emergent properties at several levels of hierarchical organization. …”
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1736
Knock-in Kcnh2 rabbit model of long QT syndrome type-2, epilepsy, and sudden death
Published 2025-04-01“…Abstract Background Long QT Syndrome Type-2 (LQT2) is due to loss-of-function KCNH2 variants. KCNH2 encodes Kv11.1 that forms a delayed-rectifier potassium channel in the brain and heart. …”
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1737
Control over biopower in cognitive and surveillance capitalism
Published 2023-01-01“…Power can achieve an effective command over the entire life of the population only when it becomes an integral, vital function that every individual embraces and reactivates of his or her own accord. …”
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1738
Resistência do solo à penetração, após o tráfego com dois tipos de pneus utilizando-se um equipamento para ensaio dinâmico Soil penetration resistance after the traffic with two ty...
Published 2003-08-01“…<br>The main objective of this research was to evaluate the soil cone index results as a function of tyre type (radial and bias tyres) and tyre load using a single wheel testing equipment and verifying the effect on the layers after tyre traffic. …”
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1739
Un port rural antique de fond d’estuaire à Blainville-sur-Orne (Calvados)
Published 2020-12-01“…Lastly, an assessment is proposed of what has been understood about the economic functioning of this trading place, notably thanks to the abundant coin finds. …”
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1740
Double-Layer Network Model of Bank-Enterprise Counterparty Credit Risk Contagion
Published 2020-01-01“…Banks and enterprises constitute a multilayered, multiattribute, multicriteria credit-related super network due to financial transaction behaviors, such as credit, wealth management, savings, and derivatives. …”
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