Evaluation of the combined effects of manganese and thermal stress on the metabolic capacities of Arctic charr (Salvelinus alpinus) by Camille Garnier, Pierre U. Blier, Patrice Couture

“…These results suggest that Mn, combined with high temperature, may affect mitochondrial function leading to a decrease in aerobic capacity. …”
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Cardiac and Digestive Forms of Chagas Disease: An Update on Pathogenesis, Genetics, and Therapeutic Targets by Amanda Farage Frade, Hélléa Guérin, Joao Paulo Silva Nunes, Luiz Felipe Souza e Silva, Vinicius Moraes de Paiva Roda, Rafael Pedro Madeira, Pauline Brochet, Pauline Andrieux, Jorge Kalil, Christophe Chevillard, Edecio Cunha-Neto

“…IFN-γ and TNF-α signaling, which are constitutively upregulated in Chagas disease patients, negatively affect mitochondrial function and adenosine 5′-triphosphate (ATP) production–cytokine-induced mitochondrial dysfunction. …”
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Exploring the molecular characteristics of inflammatory bowel disease from the perspective of hypoxia-related genes by Lei Zheng, Lin Mou, Lingying Hao, Rui Chen, Yifei Wang, Miao Yu, Xueyan Zhang

“…BackgroundInflammatory bowel disease (IBD) constitutes a chronic inflammatory disorder affecting the gastrointestinal tract, characterized by a multifaceted pathogenesis that encompasses genetic, environmental, and immunological influences. …”
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A New Ground-Motion Prediction Model for Shallow Crustal Earthquakes in Türkiye by Ulubey Çeken, Fadime Sertçelik, Abdullah İçen

“…Additionally, a heteroscedastic model was created for aleatory variability as a function of <i>M_W</i>. The closest distance to the surface projection of the fault plane (<i>R_JB</i>) is between 0 and 350 km. …”
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Anti-reflux surgical treatment for Barrett’s oesophagus by B. F. Shevchenko, N. V. Prolom, O. M. Babii, S. O. Tarabarov, O. V. Zeleniuk

“…Anti-reflux procedures constituted the second stage to remove HH and restore an excessive dilatation of the esophageal orifice of the diaphragm by cruroraphy with correction of anti-reflux function of the cardia by fundoplication, angle of His reconstruction and providing free food passage. 11 (19.6 %) patients underwent surgery according to a new technique that provided reliable recovery of cardia physiological functions and preservation of the anatomical relation between the diaphragm and the esophageal-gastric junction and included cruroraphy and fundoplication. …”
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Clinical Case of IVUS-Guided Coronary Artery Stenting in a Patient with Chronic Renal Failure by D. K. Vasiliev, B. A. Rudenko, D. A. Feshchenko, F. B. Shukurov, A. S. Shanoyan

“…Grade 2 obesity, exogenous-constitutional. Renal microlithiasis. CKD stage 4 (GFR 29 ml/min/1.73m2). …”
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Glucocorticoid receptor gene (NR3C1) methylation, childhood maltreatment, multilevel reward responsiveness and depressive and anxiety symptoms: A neuroimaging epigenetic study by Yajing Xu, Shan Yang, Cong Cao

“…Background: Although epigenomic and environment interactions (Epigenome × Environment; Epi × E) might constitute a novel mechanism underlying reward processing, direct evidence is still scarce. …”
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Regulating Sirtuin 3-mediated mitochondrial dynamics through vanillic acid improves muscle atrophy in cancer-induced cachexia by Gahee Song, Jinbong Park, Yunu Jung, Woo Yong Park, Ja Yeon Park, Se Jin Jung, Beomsu Kim, Minji Choi, Sang Hee Kim, Seong-Kyu Choe, Hyun Jeong Kwak, Junhee Lee, Kil Yeon Lee, Kwang Seok Ahn, Jae-Young Um

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Resisting While Producing: Do-It-Yourself Ethics in Turkiye’s Punk Scene by Ece N. Alparslan, Şengül İnce

“…Scott (1992/2014) stated that the main function of subcultures is to be a space in which people can distribute opposing discourses freely and without fear. …”
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Genome-wide microsatellite characterization and their marker development and transferability in Broussonetia Species by Xiaowen Jia, Hanyu Li, Ying Han, Lu Wang, Chanjuan Lai, Xi Liu, Pan Li, Zupei Lei, Yonghua Zhang

“…Genic-mapped SSRs may regulate biological processes by influencing gene activity and protein function. To verify SSRs polymorphism, we selected 30 ones from 10,752 potentially polymorphic SSRs loci for PCR amplification among these three species, all of which were successfully amplified and exhibited polymorphism across these three species. …”
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Exploring the distinctive characteristics of gut microbiota across different horse breeds and ages using metataxonomics by Xinxi Qin, Li Xi, Longfei Zhao, Jincheng Han, Hongxia Qu, Yajun Xu, Weiping Weng

“…BackgroundGut microbiota exerts a pivotal function in host nutrient metabolism and maturation of the mucosal immunity. …”
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BIN1 localizes the L-type calcium channel to cardiac T-tubules. by Ting-Ting Hong, James W Smyth, Danchen Gao, Kevin Y Chu, Jacob M Vogan, Tina S Fong, Brian C Jensen, Henry M Colecraft, Robin M Shaw

“…However, the functional role of BIN1 in cardiomyocytes is not known. …”
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Realismo y antirrealismo en la concepción semántica de las teorías científicas by León Olivé

“…So, if the empirical basis is constituted by applications, but in turn these are seen as parts of theories, she is committed to the view that theories must be tested against structures which are constitutive parts of themselves. …”
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Structural basis for hepatitis B virus restriction by a viral receptor homologue by Kaho Shionoya, Jae-Hyun Park, Toru Ekimoto, Junko S. Takeuchi, Junki Mifune, Takeshi Morita, Naito Ishimoto, Haruka Umezawa, Kenichiro Yamamoto, Chisa Kobayashi, Atsuto Kusunoki, Norimichi Nomura, So Iwata, Masamichi Muramatsu, Jeremy R. H. Tame, Mitsunori Ikeguchi, Sam-Yong Park, Koichi Watashi

“…To reveal how mNTCP loses the viral receptor function, we here solve the cryo-electron microscopy structure of mNTCP. …”
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CRISPR screens identify tumor‐promoting genes conferring melanoma cell plasticity and resistance by Arthur Gautron, Laura Bachelot, Marc Aubry, Delphine Leclerc, Anaïs M Quéméner, Sébastien Corre, Florian Rambow, Anaïs Paris, Nina Tardif, Héloïse M Leclair, Oskar Marin‐Bejar, Cédric Coulouarn, Jean‐Christophe Marine, Marie‐Dominique Galibert, David Gilot

“…Here, we performed in vivo gain‐of‐function CRISPR screens and identified SMAD3, BIRC3, and SLC9A5 as key actors of BRAFi resistance. …”
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GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus by Danying Chen, Zhifei Hou, Dong Jiang, Mei Zheng, Guoli Li, Yue Zhang, Rui Li, Hanxin Lin, Jinhong Chang, Hui Zeng, Ju-Tao Guo, Xuesen Zhao

“…Specifically, we demonstrated that GILT was constitutively expressed in lung epithelial cells and fibroblasts and its expression could be further induced by type II interferon. …”
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Characterization of spreading depolarizations in swine following superior sagittal sinus occlusion: a novel gyrencephalic model study by Renan Sanchez-Porras, Francisco L. Ramírez-Cuapio, Mildred A. Gutiérrez-Herrera, Ángel Alberto Puig-Lagunes, Pablo Albiña-Palmarola, Juan M. López-Navarro, Marcos Alejandro Suárez-Gutiérrez, Roberto Díaz-Peregrino, Diego A. Sandoval-Lopez, Gregor Fischer, Farzam Vazifehdan, Johannes Woitzik, Edgar Santos

“…Abstract Cerebral sinus thrombosis, which constitutes a small percentage of all strokes, usually affects young individuals and can lead to venous stroke. …”
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MRPL21-PARP1 axis promotes cisplatin resistance in head and neck squamous cell carcinoma by inhibiting autophagy through the PI3K/AKT/mTOR signaling pathway by Rui Guan, Ce Li, Ruijie Jiao, Jingao Li, Ran Wei, Chen Feng, Shengda Cao, Ye Qian, Jugao Fang, Jun Liu, Wenming Li, Dongmin Wei, Dapeng Lei

“…Abstract Background Head and neck squamous cell carcinoma (HNSCC) constitutes a major clinical challenge that severely affects patient survival. …”
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UNEXPECTED SPONTANEOUS REGRESSION IN CLL AFTER LETROZOLE TREATMENT: COINCIDENCE OR CONNECTION? by Ennur Ramadan, Mesut Seker, Guven Cetin

“…Estrogen is known to influence B-cell function and survival, particularly through its interaction with Estrogen Receptors (ER). …”
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IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms by Qi Wu, Shuai Zhang, Peng Liu, Wei Xie, Guido Kroemer, Oliver Kepp, Bei Li, Pan Hui, Ai-Ling Tian, Marion Leduc, Sabrina Forveille, Peter Hamley, Warren Galloway, Liwei Zhao, Frank Madeo, Yi Tu

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