Licensing Approach Applicable to Land Facilities Supporting Nuclear-Powered Submarines by Douglas Baroni, S Borsoi, M Mattar Neto, P Oliveira, M Maturana

“…Due to the innovation of this type of installation in Brazil, there is no specific regulation for its licensing, constituting a unique situation for both the Brazilian Navy (applicant) and the National Nuclear Energy Commission - CNEN (Brazilian Nuclear Licensing Agency, which, in the near future, will have its function incorporated into the National Nuclear Safety Authority, ANSN). …”
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Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb Lymphedema by Sara Bernasconi, Giovanni Maria Oriolo, Giovanni Farina, Andrea Aliverti, Antonella Lomauro

“…A wearable device, constituted by two boards with 2 IMUs, connected by a flexible flat cable, was designed and developed for placement across targeted joints. …”
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Terrestrial Spatial Distribution and Summer Abundance of Antarctic Fur Seals (Arctocephalus gazella) Near Palmer Station, Antarctica, From Drone Surveys by Gregory D. Larsen, Megan A. Cimino, Julian Dale, Ari S. Friedlaender, Marissa A. Goerke, David W. Johnston

“…Using repeat animal counts and photogrammetric data products, we modeled fur seal abundance at survey sites over the period of observation, modeled habitat suitability based on fine‐scale topographic habitat characteristics, and estimated abundance across terrestrial habitats near Palmer Station as a function of these products. High habitat suitability was most associated with low‐slope and low‐elevation inshore terrain and with relatively dry, sun‐exposed, and wind‐sheltered locations, and estimated peak abundance occurred on March 11 (day 71) of 2020. …”
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Neuroimaging Insights into the Public Health Burden of Neuropsychiatric Disorders: A Systematic Review of Electroencephalography-Based Cognitive Biomarkers by Evgenia Gkintoni, Apostolos Vantarakis, Philippos Gourzis

“…<i>Background and Objectives</i>: Neuropsychiatric disorders, including schizophrenia, bipolar disorder, and major depression, constitute a leading global public health challenge due to their high prevalence, chronicity, and profound cognitive and functional impact. …”
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Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway. by Hui H Zhang, Jingxiang Huang, Katrin Düvel, Bernard Boback, Shulin Wu, Rachel M Squillace, Chin-Lee Wu, Brendan D Manning

“…One direct substrate that is inhibited by Akt-mediated phosphorylation is the tuberous sclerosis complex 2 (TSC2) protein, which associates with TSC1 and acts as a critical negative regulator of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1). Loss of function of the TSC1-TSC2 complex results in constitutive mTORC1 signaling and, through mTORC1-dependent feedback mechanisms and loss of mTORC2 activity, leads to a concomitant block of Akt signaling to its other downstream targets.…”
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Predictors of macular pigment and contrast threshold in Spanish healthy normolipemic subjects (45-65 years) with habitual food intake. by Begoña Olmedilla-Alonso, Elena Rodríguez-Rodríguez, Beatriz Beltrán-de-Miguel, Rocío Estévez-Santiago, Milagros Sánchez-Prieto

“…The HDL-cholesterol would also act indirectly on the CT improving the visual function.…”
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Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer. by Anju Singh, Vikas Misra, Rajesh K Thimmulappa, Hannah Lee, Stephen Ames, Mohammad O Hoque, James G Herman, Stephen B Baylin, David Sidransky, Edward Gabrielson, Malcolm V Brock, Shyam Biswal

“…<h4>Conclusions</h4>This is the first study to our knowledge to demonstrate that biallelic inactivation of KEAP1 is a frequent genetic alteration in NSCLC. Loss of KEAP1 function leading to constitutive activation of NRF2-mediated gene expression in cancer suggests that tumor cells manipulate the NRF2 pathway for their survival against chemotherapeutic agents.…”
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Cultural Resilience from Sacred to Secular: Ritual Spatial Construction and Changes to the Tujia Hand-Waving Sacrifice in the Wuling Corridor, China by Tianyi Min, Tong Zhang

“…Overall, this study reveals a unique path for non-literate ethnic groups to achieve the intergenerational transmission of cultural memory through the collusion of material symbols and physical art practices, as well as the possibility of embedding the hand-waving sacrifice ritual into contemporary spatial practice through symbolic translation and functional extension in the context of social function inheritance and variation. …”
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Efficiency of neutralization of electric charges on the surface of dielectric nonwoven fabric of two dual and triode electrode systems by B. Yahiaoui, A. Messaoudene, A. Melahi, A. Rahmani, B. Bendahmane, L. Dascalescu

“…The static charges are often considered annoying and constitute one of the main sources of hazards. Thus, their neutralization is more than necessary. …”
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Esophageal cancer related gene-4 is a choroid plexus-derived injury response gene: evidence for a biphasic response in early and late brain injury. by Sonia Podvin, Ana-Maria Gonzalez, Miles C Miller, Xitong Dang, Hannah Botfield, John E Donahue, Arwa Kurabi, Matthew Boissaud-Cooke, Ryan Rossi, Wendy E Leadbeater, Conrad E Johanson, Raul Coimbra, Edward G Stopa, Brian P Eliceiri, Andrew Baird

“…Accordingly, augurin would play a constitutive inhibitory function in normal CNS while down regulation of Ecrg4 gene expression in injury, like in cancer, dysinhibits proliferation.…”
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The linc009 negatively regulates cell apoptosis in turbot (Scophthalmus maximus L.) during bacterial challenge by Beibei Wang, Xiaocheng Zhu, Xinghua Zhuang, Xiaoli Liu, Zhongyi Wang, Ning Yang, Chao Li

“…This study provided valuable insights into the function and regulatory mechanism of lncRNAs in teleost.…”
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Unlocking Apoptotic Pathways: Overcoming Tumor Resistance in CAR‐T‐Cell Therapy by Zhanna Zhang, Manqi Su, Panruo Jiang, Xiaoxia Wang, Xiangmin Tong, Gongqiang Wu

“…We assess the impact of the tumor microenvironment (TME) on CAR‐T cell function and propose dual‐targeting CAR‐T cells to simultaneously address both myeloid‐derived suppressor cells (MDSCs) and tumor cells. …”
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Análisis del comportamiento del material de la arteria aorta ascendente para su modelación// Behavior analysis of the ascending aorta artery material for modeling by Diana Otero‐Martínez, Luis L. Otero‐Pereiro, Vladimir González‐Fernandez

“…<br /><br /><strong>Key words:</strong> arterial tissue engineering, constitutive modelling, elasticity, aortic wall, characteristics of arteries…”
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Perturbation based privacy preservation and classification using Jaya Algorithm and Dragonfly Inspired Algorithm by Dipanwita Sen, Bhupati Bhusan Mishra, Prasant Kumar Pattnaik

“…The patients’ health details constitute private personal information. They should not be disclosed. …”
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Tracking Long-Term Ozone Pollution Dynamics in Chinese Cities with Meteorological and Emission Attribution by Hongrui Li, Xiaoyong Liu, Zijian Liu, Mengyang Li, Tong Wu, Peicheng Li, Peng Zhou

“…Although China has achieved substantial reductions in particulate matter pollution, continually rising ground-level ozone now constitutes the primary challenge to further air-quality improvements. …”
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A Novel YWHAG Variant L173S Causes Developmental and Epileptic Encephalopathy by Disrupting the Hydrophobic Internal Protein Structure by Yuan Jin, Qian Niu, Shan Na Liang, Mei Ling Luo, Xiao Lin Su, Zhe Tao

“…This may provide insights into the functional mechanisms of YWHAG and potential therapeutic strategies.…”
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Cross-cultural adaptation, reliability and validity analysis of the Cantonese-Chinese Manchester Oxford Foot Questionnaire for Foot and Ankle Disorder (Manchester-Oxford Foot Quest... by Shu MC Chia, Leung P Ho, Violet Man-Chi Ko, He Xin, Long CB Chow, Patrick Shu-Hang Yung, Samuel Ka-Kin Ling

“…The overall reliability coefficient constituted 0.86 (intraclass correlation coefficient = 0.72–0.93). …”
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Rasism i seminarierummet: Strategisk empati och de svåra känslornas pedagogik by Magnus Rodell

“…The text concludes with a discussion of Michalinos Zembyla’s concepts of strategic empathy and reconciliatory perspective. Although this constitutes a difficult-to-navigate pedagogical methodology, the concepts can function as tools to tackle difficult and emotionally invested seminar situations.  …”
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The exocyst complex controls multiple events in the pathway of regulated exocytosis by Sofía Suárez Freire, Sebastián Perez-Pandolfo, Sabrina Micaela Fresco, Julián Valinoti, Eleonora Sorianello, Pablo Wappner, Mariana Melani

“…Eukaryotic cells depend on exocytosis to direct intracellularly synthesized material toward the extracellular space or the plasma membrane, so exocytosis constitutes a basic function for cellular homeostasis and communication between cells. …”
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CD36 promotes iron accumulation and dysfunction in CD8 T cells via the p38-CEBPB-TfR1 axis in earlystage hepatocellular carcinoma by Yifei Qin, Fei Huo, Zhuan Feng, Jialu Hou, Yaxin Ding, Quancheng Wang, Yu Gui, Ziwei Yang, Jiali Yang, Gang Zhou, Ling Li, Jianli Jiang, Lingmin Kong, Shijie Wang, Gang Nan, Dingqiao Xu, Xiaohang Xie, Lijuan Wang, Qian He, Ruibin Yang, Peng Lin, Huijie Bian, Zhi-Nan Chen, Jiao Wu

“…Depletion of CD36 in CD8+ T cells inhibited the upregulation of TfR1 and the increase of iron levels. Furthermore, constitutively activated nuclear factor erythroid 2-related factor 2 (NRF2) effectively suppressed lipid peroxidation, thereby preserving the effector functions of intratumoral CD8+ T cells and ultimately inhibiting tumor growth. …”
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