<i>IGFBP5</i> Promotes Atherosclerosis in APOE^−/− Mice Through Phenotypic Transformation of VSMCs by Aoqi Xiang, Hua Guan, Peihong Su, Lusha Zhang, Xiaochang Chen, Qi Yu

“…Atherosclerosis constitutes a pathological process underlying cardiovascular diseases. …”
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Numerical Simulation of Electromagnetic Nondestructive Testing Technology for Elasto–Plastic Deformation of Ferromagnetic Materials Based on Magneto–Mechanical Coupling Effect by Xiangyi Hu, Xiaoqiang Wang, Haichao Cai, Xiaokang Yang, Sanfei Pan, Yafeng Yang, Hao Tan, Jianhua Zhang

“…This paper also investigates the effect of elasto–plastic deformation on the transient magnetic flux signal, a quantitative hyperbolic tangent model between B<i>z</i>_pp (peak–peak value of the normal component of magnetic flux signal) and elastic stress, and the exponential function relationship between B<i>z</i>_pp and plastic deformation is established. …”
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Orthosteric STING inhibition elucidates molecular correction of SAVI STING by Tao Xie, Max Ruzanov, David Critton, Leidy Merselis, Joseph Naglich, John S. Sack, Ping Zhang, Chunshan Xie, Jeffrey Tredup, Laurel B. Stine, Cameron Messier, David L. Hope, Janet Caceres-Cortes, Luciano Mueller, Alaric J. Dyckman, John A. Newitt, Asmita Choudhury, Stephen C. Wilson

“…Questions persist about the molecular properties needed to distinguish between a STING activator and inhibitor, particularly within SAVI disease, a monogenic autoinflammatory disease that renders STING constitutively active, and how different conformations correlate to function. …”
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TNIK-driven regulation of ERK5 transcriptional activity in endothelial cells by Venkata Subrahmanya Kumar Samanthapudi, Sivareddy Kotla, Nhat-Tu Le

“…Extracellular signal-regulated kinase 5 (ERK5) is essential for cardiovascular development and endothelial cell (EC) function. Activation of ERK5 through MEK5-mediated phosphorylation at threonine 218 and tyrosine 220 (T218/Y220) drives the transcriptional activation of myocyte enhancer factor-2 (MEF2), promoting the expression of KLF2 and KLF4—key transcription factors that maintain vascular homeostasis. …”
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Nutrigenomic and Nutritional Analyses Reveal the Effects of Pelleted Feeds on Asian Seabass (Lates calcarifer). by Si Yan Ngoh, Daniel Tan, Xueyan Shen, Purushothaman Kathiresan, Junhui Jiang, Woei Chang Liew, Natascha May Thevasagayam, Hsiao Yuen Kwan, Jolly M Saju, Sridatta R S Prakki, Chin Heng Goh, Hong Ching Wong, Tai Teck Chan, Miklós Mézes, László Orbán

“…Significant enrichment of genes with growth-related function tallied with the morphological data measured. …”
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DISCUSSIONS REGARDING A POSSIBLE GOVERNMENT GUARDIANSHIP CONTROL OVER ADMINISTRATIVE ACTS by Constantin Claudiu ULARIU

“…The Government, as an emblematic and fundamental exponent of executive power within the framework of the rule of law, alongside the President of Romania, constitutes a determinant structure of representative democracy. …”
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Telecom Fraud Recognition Based on Large Language Model Neuron Selection by Lanlan Jiang, Cheng Zhang, Xingguo Qin, Ya Zhou, Guanglun Huang, Hui Li, Jun Li

“…In the realm of natural language processing (NLP), text classification constitutes a task of paramount significance for large language models (LLMs). …”
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Late Byzantine spiritual guidance in the letters of the metropolitan of Chalcedon to the nun Eulogia by Alevtina Matveeva

“…The spiritual letters themselves serve as instruments of influence as their function extends beyond communication and maintaining social connections. …”
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Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targets. by Eumorphia G Konstantakou, Athanassios D Velentzas, Athanasios K Anagnostopoulos, Zoi I Litou, Ourania A Konstandi, Aikaterini F Giannopoulou, Ema Anastasiadou, Gerassimos E Voutsinas, George Th Tsangaris, Dimitrios J Stravopodis

“…Our advanced melanoma-specific catalogue proved to contain 6,681 unique proteins, which likely constitute the hitherto largest single cell-line-derived proteomic collection of the disease. …”
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Informal caregiving following stroke: a qualitative exploration of carer self-identification, care-related language and support experiences by Richard Brown, Audrey Bowen, Bethany Harcourt

“…The study took place from September 2021 to April 2024.Participants 18 adults (aged 18 years and above) who had provided care or support to a friend or family member after a stroke that occurred at least 1 year prior to participation completed the study.Results Five main themes were developed: (1) adopting and adjusting to the care role, (2) accessibility of support, (3) perceptions of support, (4) acceptability of care-related language and terminology and (5) function of care-related language and terminology. …”
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INNOVATIVE ASPECTS OF OPEN INGUINAL HERNIA SURGERY: REDUCING COMPLICATIONS AND PREVENTING RECURRENCES by К. Рахманов, О. Хужамов, С. Давлатов, Б. Хамдамов, С. Янченко, Н. Абдуллаєва, З. Джалілова

“… Inguinal hernias constitute a significant portion of surgical pathology and remain among the most common reasons for seeking surgical consultation. …”
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Altered lower leg muscle activation patterns in patients with cerebral palsy during cycling on an ergometer by Alves-Pinto A, Blumenstein T, Turova V, Lampe R

“…Ana Alves-Pinto,1,* Tobias Blumenstein,1,* Varvara Turova,1 Ren&amp;eacute;e Lampe1,2 1Research Unit of the Buhl-Strohmaier Foundation for Cerebral Palsy and Paediatric Neuroorthopaedics, Orthopaedic Department, Klinikum rechts der Isar, 2Markus W&amp;uuml;rth Professorship, Technical University of&amp;nbsp;Munich, Munich, Germany *These authors contributed equally to&amp;nbsp;this work Objective: Cycling on a recumbent ergometer constitutes one of the most popular rehabilitation exercises in cerebral palsy (CP). …”
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Degeneration modulates retinal response to transient exogenous oxidative injury. by Michal Lederman, Shira Hagbi-Levi, Michelle Grunin, Alexey Obolensky, Eduard Berenshtein, Eyal Banin, Mordechai Chevion, Itay Chowers

“…<h4>Methods</h4>Retinal oxidative injury was induced in degenerating retinas (rd10) and in control mice (WT) by intravitreal injections of paraquat (PQ). Retinal function and structure was evaluated by electroretinogram (ERG) and histology, respectively. …”
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Innovative Strategies For Social-Economic Development Financial Strategies In The Development Country by Chukwu Anthony Ogochukwu, Karina Kasztelnik

“…This research paper summarizes the arguments and counterarguments within the scientific discussion on the Small and medium scale enterprises constitute the backbone of any nations economic development and had remained a major contributor in poverty alleviation, employment generation, and industrialization. …”
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SENP5 promotes endometrial cancer cell growth by regulating β-catenin deSUMOylation to enhance GPX4-resistance to ferroptosis by Ziyuan Wang, Yongmei Zhang, Yongfang Zhang, Qiuhong Deng, Yandong Xi, Wanxia He, Xiaolong Ma

“…Nonetheless, the function of SENP5 in EC and its regulation of EC progression through the related mechanism of desumoylation modification remain elusive. …”
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Similarities and Differences between Media Reporting and Fieldwork on Interethnic Relations in Bosnia and Herzegovina (2016–2024) by Bogdan D. Dražeta

“…I believe that pointing out this issue could represent a small contribution to developing a different view of how ethnic communities in Bosnia and Herzegovina function among themselves and to what extent the media speak differently about it. …”
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GATOR1 gene variants in focal epilepsy by Kovačević Maša, Vojvodić Nikola, Novaković Ivana

“…The genes listed above code the three subunits that comprise the GTPase-activating protein (GAP) activity towards Rags 1 (GATOR1) complex, a negative regulator of the mechanistic target of rapamycin (mTOR) complex 1 (mTORC1). Loss of function of GATOR1 leads to constitutive mTORC1 activation that is linked to various malformations of cortical development (MCD), most notoriously focal cortical dysplasia (FCD), but has also been linked to epilepsy in the absence of overt MCD. …”
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PRODUCTIVITY AND EFFICIENCY OF MAIZE (ZEA MAYS) FARMERS IN ADAMAWA STATE, NIGERIA by Abdu Karniliyus TASHIKALMA, Dengle Yuniyus GIROH

“…Furthermore, the stochastic cost function analysis indicated that 80.24% variations in allocative efficiencies were as a result of the variables included in the model. …”
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THE PROPOSAL MODEL OF RATIONAL WORKFORCE ASSIGNMENT IN DOKUZ EYLUL UNIVERSITY BY ANALYTIC HIERARCHY PROCESS BASED 0-1 INTEGER PROGRAMMING by Yılmaz GÖKŞEN, Hakan AŞAN, Onur DOĞAN, Mustafa ÜNLÜ, Osman PALA

“…The coefficients of the variables in the objective function of the assignment model constitute potential contributions of employees. …”
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Anti-inflammatory actions of ripasudil ameliorate experimental autoimmune uveoretinitis in the acute phase by Tomohito Sato, Masaru Takeuchi, Kozo Harimoto, Hideaki Someya, Masataka Ito, Yoshiaki Nishio

“…Introduction Rho-associated protein kinases (ROCKs) are a key regulator of T cell function, influencing a wide range of processes from activation to differentiation. …”
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