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1541
Mediating effect of kinesiophobia between self-efficacy and physical activity levels in post-CABG patients: protocol for a prospective, multicentre, cross-sectional study in China
Published 2022-07-01“…Introduction Physical activity (PA) can improve cardiac function, exercise capacity, and quality of life, in addition to reducing mortality by 20%–30% and preventing the recurrence of adverse cardiovascular events in patients following coronary artery bypass graft (CABG). …”
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1542
Hydrochemical Characteristics and Control Factors of Strontium Enrichment of Groundwater in the Eastern Sanjiang Plain, China
Published 2025-01-01“…Groundwater with a Sr content over 0.40 mg/L constituted 7.32% of the total samples. The siliceous rocks and basalts present in this region supply the foundational material for Sr2+ enrichment. …”
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1543
The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome
Published 2015-01-01“…Our patients shared multiple homozygous genomic regions; ten shared regions were >1 Mb in length and constituted 0.99% of the genome. DCAF17, encoding a transmembrane nuclear protein of uncertain function, was the only gene identified in a homozygous region known to cause hypogonadotropic hypogonadism. …”
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1544
Energy dissipation properties of backfill materials under compaction in solid waste backfill mining
Published 2025-05-01“…The relationship between particle crushing energy and axial strain is approximated by a linear function. The energy consumed by particle breakage constitutes a small proportion (0.7%∼7.8%) of the total energy consumption for specimen deformation, while the majority of energy consumption is attributed to inter-particle friction, especially in the later compaction stage. …”
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1545
Bio-Composite Nanogels Based on Chitosan and Hyaluronic Acid for the Treatment of Lung Infections
Published 2024-11-01“…Pathogen infections constitute a serious problem in the field of lung diseases, especially in severe conditions such as chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS). …”
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1546
Advances in immune microenvironment and immunotherapy strategy for colorectal cancer
Published 2022-08-01“…T cells, B cells, macrophages, and other immune cells together constitute a complex immune microenvironment and participate in the development and progression of colorectal cancer. …”
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1547
Genetic association analysis of ATP binding cassette protein family reveals a novel association of ABCB1 genetic variants with epilepsy risk, but not with drug-resistance.
Published 2014-01-01“…Epilepsy constitutes a heterogeneous group of disorders that is characterized by recurrent unprovoked seizures due to widely different etiologies. …”
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1548
LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling
Published 2025-07-01“…Silencing of NACC2 in TP53 wildtype NCI-H460 or TP53-null NCI-1299 cell lines replicated many of these changes, with profiles varying as a function of p53 status. Stable overexpression of HDM2 increased LINE-1 ORF1p in cancer cell lines. …”
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1549
The Role of Protein Kinase C During the Differentiation of Stem and Precursor Cells into Tissue Cells
Published 2024-11-01“…Furthermore, PKC is capable of directly phosphorylating transcription factors with pivotal function for a certain developmental process. Ultimately, profound knowledge about the role of distinct PKC isoforms and the involved signaling pathways during differentiation constitutes a promising tool to improve the use of stem cells in regenerative therapies by precisely manipulating the activity of PKC or downstream effectors.…”
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1550
Samfundssikkerhed i Arktis – en ny dagsorden for Arktisk Råd?
Published 2025-05-01“…This article discusses how societal security may be interpreted in an Arctic context and investigates how preparedness is organized in the region with a special emphasis on the function and meaning of the Arctic Council and other collaborative organizations in a future perspective. …”
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1551
Structure of the EphB6 receptor ectodomain.
Published 2021-01-01“…To further our understanding of Eph receptor function, we crystallized the EphB6-ECD and determined its three-dimensional structure using X-ray crystallography. …”
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1552
Extreme genetic fragility of the HIV-1 capsid.
Published 2013-01-01“…The capsid (CA) domain of the HIV-1 Gag protein is under strong pressure to conserve functional roles in viral assembly, maturation, uncoating, and nuclear import. …”
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1553
The Rvv two-component regulatory system regulates biofilm formation and colonization in Vibrio cholerae.
Published 2023-05-01“…Mutating RvvB to mimic constitutively active and inactive versions of the RR only impacted phenotypes in the ΔrvvA genetic background. …”
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1554
Activities of daily living mediate the association between balance and falls in middle aged and older adults
Published 2025-08-01“…Abstract Falls constitute a significant public health issue affecting middle-aged and older adults.The consequences of falls extend beyond physical injuries and compromised quality of life to encompass psychological and socioeconomic dimensions. …”
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1555
Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells.
Published 2009-01-01“…The Transforming Growth Factor (TGF) beta signalling family includes morphogens, such as Nodal and Activin, with important functions in vertebrate development. The concentration of the morphogen is critical for fate decisions in the responding cells. …”
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1556
TNFα levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine.
Published 2013-01-01“…Latent changes in trigeminal ganglion structure and function resembling inflammatory conditions may predispose to acute attacks of migraine pain. …”
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1557
Briséis et la plainte funèbre de l’épouse dans l’épopée homérique
Published 2012-05-01“…In her lament for Patroclus, Briseis speaks with the voice of someone close to the deceased and assumes the function of the mourning female normally assigned to the mother or wife. …”
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1558
Distribution and laterality of concha bullosa in patients with different cranial skeletal types: a retrospective analysis among cases with concha bullosa
Published 2025-05-01“…Abstract Objective Concha bullosa, a common anatomical variation characterized by air-filled cavities in the turbinate bones, can influence sinonasal function and surgical planning. This study aims to evaluate the distribution, laterality, and cranial skeletal type associations of concha bullosa (CB) among patients with confirmed CB findings on computed tomography (CT) scans. …”
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1559
Deciphering T-cell exhaustion in the tumor microenvironment: paving the way for innovative solid tumor therapies
Published 2025-04-01“…The primary function of these T-cells is to detect and eliminate tumor cells. …”
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1560
MATHEMATICAL SUPPORT OF THE INTELLIGENT INFORMATION SYSTEM OF ASSESSING THE OBJECT STATE
Published 2017-11-01“…The following result was obtained: the suggested mathematical models for predicting the outcome of myocardial infarction that were developed with the use of the method of discriminant function and took into account human blood values can prevent sudden coronary death and improve the diagnostic efficiency. …”
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