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1301
Role of Pseudoexons and Pseudointrons in Human Cancer
Published 2013-01-01“…In healthy individuals, alternative and constitutive splicing processes function with a high degree of precision and fidelity in order to ensure the correct working of this machinery. …”
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1302
Conservation’s green illusion: Nitrogen thresholds as critical determinants of extinction risk in specialist herbivores
Published 2025-10-01“…Sub-threshold habitats can function as ecological traps, silently undermining translocation, reproduction, and survival even in structurally intact forests. …”
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1303
„Россия поднимается с колен” четверть века спустя: медиалингвистический анализ политической мифологемы...
Published 2025-06-01“…The mythologeme – as a verbal carrier of the myth, a complex type of a sign with the function of a concept and figurative content – serves as a symbolic encoding of the world and consolidation of society. …”
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1304
Referenece and its effect on the textuality in (farewell sermon)
Published 2022-10-01“…The study starts with an introduction to linguistics and textuality and its function. It deals with a short introduction of textuality in the Arabic rhetoric because Arabic rhetoric constitutes an important part in the modern linguistics both theoretically and practically. …”
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1305
Le développement de l’enseignement clinique à Paris et la création de l’école clinique interne de l’hôpital de la Charité
Published 2011-12-01“…The superiority gained by that hospital due to the novelty of the teaching that was provided in it explained why, when health schools were created by the National Convention on 14 Frimaire An III (December 4, 1794), it was the place that was chosen to establish the first school of clinical medicine that would be provided with premises most specially adapted to its function. Because of the budgetary contingencies associated with the political situation, the yard happened to be interrupted several times, but was eventually carried through. …”
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1306
THE METHOD OF OPTIMIZATION OF THE SET OF TECHNICAL FACILITIES TO PROVIDE AVIATION SAFETY AND SECURITY
Published 2016-12-01“…The actuality of problem of optimizing the set of technical facilities to provide aviation safety and security is determined by the necessity to develop aviation security provision system taking into account the analysis of threats while ensuring balance between expenses on security support and possible damage from the act of unlawful interference.The offered method of optimization consists of two main stages: determination of the optimal total expenses and determination of the optimal set of technical facilities.The first stage is devoted to analysing the threats and solving the task of optimization of total expenditures on the technical aids set used to ensure aviation safety and security which means searching for the minimum of total expenses goal function. These expenses constitute a sum of expenses spent on technical aids set and damage from the act of unlawful interference.The second methodological stage deals with setting the task of parameters synthesis. …”
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1307
Fantastic Realia: Some Lexical Correspondences (Russian-Romanian)
Published 2021-09-01“…Moreover, another present-day function was assigned to folkloric, mythological elements (the mythemes) through their animated metamorphosis into the realm of video games, already being annotated, listed online. …”
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1308
Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity.
Published 2024-12-01“…By mutating acetylation sites on Ydj1's J-domain to either abolish or mimic constitutive acetylation, we observed that preventing acetylation had no noticeable phenotypic impact, whereas acetyl-mimic mutants exhibited various defects indicative of impaired Ydj1 function. …”
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1309
Multi-Scale Agent-Based Multiple Myeloma Cancer Modeling and the Related Study of the Balance between Osteoclasts and Osteoblasts.
Published 2015-01-01“…Furthermore, the drug synergism analysis function of the model revealed that restoring the balance between OBs and OCs can significantly increase the efficacy of drugs against tumor cells.…”
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1310
Peripheries of Narration and Spatial Poetics in Wilkie Collins’s The Moonstone
Published 2022-12-01“…Spatial poetics in the novel functions in a way in which despite the myriad of settings that constitute the story, narrative discourse privileges some places while putting the others into the peripheries. …”
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1311
In Vitro Murine Hematopoiesis Supported by Signaling from a Splenic Stromal Cell Line
Published 2018-01-01“…To analyse the hematopoietic support function of 5G3, specific signaling pathway inhibitors were tested for the ability to regulate cell production in vitro in cocultures of stroma overlaid with bone marrow-derived hematopoietic stem/progenitor cells. …”
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1312
Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.
Published 2014-01-01“…Here we have identified multiple sites of CPC autophosphorylation on yeast Sli15 that are located within its central microtubule-binding domain and examined the functional significance of their phosphorylation by Ipl1 through mutation of these sites, either to non-phosphorylatable alanine (sli15-20A) or to acidic residues to mimic constitutive phosphorylation (sli15-20D). …”
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1313
Modeling and experimental investigation of quasi-zero stiffness vibration isolator using shape memory alloy springs
Published 2025-02-01“…We began by reformulating the static constitutive equation of the SMA spring, and the torsional strain of the spring was taken into account into the static constitutive equation. …”
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1314
The pattern of the NOS isoforms expression in arcuate nucleus of hypothalamus in experimental hypertension
Published 2017-03-01“…One of the main conditions of the proper neuronal function is combination of their functional stability and plasticity, which is strictly dependable on adequate blood supply, metabolic and trophic processes. …”
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1315
Coalescence formation of muonic atoms at RHIC
Published 2025-02-01“…The discovery of exotic muonic atoms, including antimatter hydrogen muonic atoms and kaon muonic atoms, constitutes a milestone in our ability to make and study new forms of matter. …”
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1316
Parent brain responses to child facial and vocal communication: What different methodologies reveal about parenting cognitions and practices as well as their moderation by parental...
Published 2025-09-01“…Parenting is constituted of caregiving cognitions and practices, based in evolution and biology as well as culture and context, and lodged in nervous system structure and function. …”
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1317
A Novel Fatigue Damage Model of Rock considering Temperature Effects
Published 2020-01-01“…The deformation rules and failure types of rock fatigue damage at different temperatures are quite different, and existing constitutive theory cannot describe them quantitatively. …”
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1318
Indirect and suboptimal control of gene expression is widespread in bacteria
Published 2013-04-01“…Two common types of indirect control are constitutive expression and regulation by growth rate; these occur for genes with diverse functions and often seem to be suboptimal. …”
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1319
Late reconstruction of a traumatized hand with loss of multiple fingers
Published 2017-09-01“…Late reconstruction constitutes the second part of this difficult task. …”
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1320
Immunotherapy Using Dendritic Cells against Multiple Myeloma: How to Improve?
Published 2012-01-01“…Immunological inhibitory cytokines, such as TGF-β, IL-10, IL-6 and VEGF, which are produced from myeloma cells, can modulate antitumor host immune response, including the abrogation of DC function, by constitutive activation of STAT3. Therefore, even the immune responses have been observed in clinical trials, the clinical response was rarely improved following DC vaccinations in MM patients. …”
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