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601
An unconventional T cell nexus drives HCK-mediated chronic obstructive pulmonary disease in miceResearch in context
Published 2025-05-01“…Methods: Studies primarily utilised gene-targeted mice with a gain-of-function mutation in Hck that rendered the enzyme constitutively active. …”
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602
INVERSION AS A RHETORICAL FIGURE IN ENGLISH MODERNISTIC DISCOURSE (SYNERGETIC AND PSYCHOLINGUISTIC DIMENSIONS)
Published 2024-11-01“…The article elucidates synergetic and psycholinguistic aspects of functioning of the inverted text contexts’ in J. Joyce’s literary works. …”
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603
Creep failure characteristics and damage creep model of red layer soft rock based on Perzyna viscoplastic theory
Published 2025-04-01“…The results show that: (1) The model curves in this paper fit well with the test data, indicating that Weibull distribution function is feasible to describe rock creep damage, and the accuracy and rationality of the model in this paper are verified. (2) Based on Perzyna viscoplastic theory, a more accurate viscoplastic strain expression was established to describe accelerated creep. (3) By defining the critical point damage variables of different creep stages, the relationship between rock creep deformation and damage can be better reflected, which makes up the shortcoming that Nishihara model cannot describe accelerated creep, and enriches the creep constitutive theory of rock materials.…”
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604
Increased Incidence of Chronic Obstructive Pulmonary Disease in Women Due to Long-Term Passive Smoking
Published 2025-08-01“…The LPS group demonstrated: higher prevalence of preserved ratio impaired spirometry (PRISm, 5.74% vs 2.91%); increased annual exacerbation frequency (p < 0.05), elevated systemic inflammatory markers (p < 0.05), greater symptom severity (p < 0.05).Conclusion: Our findings demonstrate that chronic passive smoke exposure constitutes an independent risk factor for COPD development in women, associated with higher disease prevalence, accelerated pulmonary function decline, increased exacerbation frequency and enhanced systemic inflammation.Keywords: women, passive smoking, chronic obstructive pulmonary disease, pulmonary function, preserved ratio impaired spirometry…”
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605
Deciphering key parameters enhancing lentiviral vector producer cells yields: Vector components copy number and expression
Published 2025-03-01“…However, Pol and reverse transcriptase expressions were shown to be better indicators of potential functional titers. Envelope and transfer vector expression levels were key to attaining high functional particles yields. …”
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606
Optimizing uni-compartmental knee arthroplasty: the impact of preoperative planning and arithmetic hip-knee-ankle angle
Published 2025-03-01“…Results The proportion of the constitutional alignment group in the planning group was higher than that in the conventional group (86% vs. 66%) (p = 0.033). …”
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607
Le processus incapacitant au cours du vieillissement : rôle de l’exercice/activité physique
Published 2007-12-01“…The definitions of frailty, as well as the ways to measure physical exercise/activity, constitute the main inconsistencies among studies. However, most of the researches show that a regular practice of physical exercise/activity decreases the age-related declines in both physiological status and functional fitness. …”
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608
THE FACETED S100B PROTEIN: THE JEKYLL/HYDE SIDE
Published 2025-08-01“…While many functions have been attributed to the protein, at present it appears to have a double concentration-dependent role. …”
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609
A Critical Review on the Book Theory of Systems and Paradigm Shift in Sociology
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610
Identification and Characterization of bZIP Gene Family Combined Transcriptome Analysis Revealed Their Functional Roles on Abiotic Stress and Anthocyanin Biosynthesis in Mulberry (...
Published 2025-06-01“…As described, we systematically explored the structures and functions of the bZIP gene family in <i>Morus alba</i>. …”
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611
SLM Ti12Mo6Zr2Fe-xCu implants: in-situ precipitating nanoscale Ti-Cu phase induced bio-functional properties
Published 2025-12-01“…The β-Ti phase along with a few ω-Ti, α"-Ti and Ti2Cu phases constituted the SLM TMZF-xCu microstructures especially in high Cu doped alloys. …”
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612
Long-term cognitive impairment, psychological disorders, and functional limitations in COVID-19 survivors: A 2-year follow-up at a tertiary care hospital in Bengaluru
Published 2025-01-01“…After administering a semi-structured interview constituting sociodemographic details, treatment profile, and validated assessment tools, subjects were categorized based on anxiety, depression, cognitive failure, and functional disability scores accordingly. …”
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613
Digestive system-related pathophysiological symptoms of Sasang typology: Systematic review
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614
Geometrically Nonlinear Analysis of Laminated Composite Plates subjected to Uniform Distributed Load Using a New Hypothesis: the finite element method (FEM) Approach
Published 2020-11-01“…Here, in-plane displacements made use of an inverse trigonometric shape function to account for the effect of transverse shear deformation. …”
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615
A novel network with enhanced edge information for left atrium segmentation from LGE-MRI
Published 2024-12-01“…IntroductionAutomatic segmentation of the left atrium (LA) constitutes a crucial pre-processing step in evaluating heart structure and function during clinical interventions, such as image-guided radiofrequency ablation of atrial fibrillation. …”
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616
Does the Integration of Primary Refl ex Schemas According to Masgutova’s Neurosensorimotor Refl ex Integration Improve Functioning and Quality of Life Among Children with Spectrum...
Published 2023-02-01“…Intrauterine exposure of the foetus to alcohol affects the lack of proper reflex mechanism integration, which constitutes the foundation of harmonious psychomotor, cognitive, emotional and social development.The aim: The aim of this study is to present the role of primary reflex integration disorders according to MNRI in children with the Spectrum of Foetal Alcohol Disorders (FASD), as well as to discuss the impact of integrating primary reflex disorders according to MNRI on the functioning of FASD in children.Methods: The therapy comprised 103 patients (44 girls and 59 boys) aged 1-13 years with FASD, diagnosed according to the criteria of ICD-10 (Q 86.0). …”
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Ball‐Milling‐Promoted Copper‐Catalyzed Solid‐State Radical C–H Difluoroalkylation Reactions
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619
Preparation for mitosis requires gradual CDK1 activation
Published 2025-05-01“…Conversely, shortening G2 phase by WEE1 inhibition leads to mitotic delays, which can be partially rescued by expression of constitutively active PLK1. Our results show a function for slow mitotic kinase activation through G2 phase and suggest a mechanism for how the timing of mitotic entry is linked to preparation for mitosis.…”
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620
Simulation of an M 7.1 Lateral Fault Coastal Earthquake: A Plausible Scenario for Seismic Hazard Assessment in Michoacan, Mexico
Published 2025-04-01“…An M 4.3 was used as a Green’s function to generate an M 5.1 synthetic earthquake. …”
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