Design and screening of novel endosomal escape compounds that enhance functional delivery of oligonucleotides in vitro by H. Yesid Estupiñán, Tom Baladi, Samantha Roudi, Michael J. Munson, Jeremy Bost, Oskar Gustafsson, Daniel Velásquez-Ramírez, Deepak Kumar Bhatt, Daniel Hagey, Dennis Hekman, Shalini Andersson, Samir EL Andaloussi, Anders Dahlén

“…., gapmers), while SSOs alter transcript splicing to restore or inhibit protein function. RNA interference (RNAi) is another approach to down-regulate gene expression via the RISC complex. …”
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Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function by Zeinabou Niasse‐Sy, Bo Zhao, Ajda Lenardič, Huyen Thuc Tran Luong, Ori Bar‐Nur, Johan Auwerx, Martin Wohlwend

“…This study, therefore, highlights the potential of identifying functional domains in noncoding RNAs. Delivery, or targeting of RNA domains might constitute next‐generation RNA therapeutics.…”
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Nutritional Quality, Functional Properties, and Biological Characterization of Watermeal (<i>Wolffia globosa</i>) by Parinya Boonarsa, Apichaya Bunyatratchata, Theeraphan Chumroenphat, Pornpisanu Thammapat, Tipaukson Chaikwang, Tarathep Siripan, Hua Li, Sirithon Siriamornpun

“…This study evaluated the nutritional quality, functional properties, and biological characteristics of <i>W. globosa</i>. …”
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Exploring the potential effect of electroacupuncture on cardiovascular function and lipid profiles in spontaneously hypertensive rats by Hye-Yoom Kim, Sarah Shin, Jung-Joo Yoon, You-Mee Ahn, Ji-Hye Song, Da-Som Lee, Ji-Yeun Park, Ho-Sub Lee, Jeeyoun Jung

“…Background: Investigating the effects of electroacupuncture (EA) treatment on cardiovascular function and aortic lipid profiles in spontaneously hypertensive rats (SHR) constitutes the foundational focus of this study. …”
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Effective least squares approximation method for estimating the rhythm function of cyclic random process by Serhii Lupenko, Małgorzata Wiatr, Andrzej Metelski

“…The general problem of least squares approximation of the rhythm function of a cyclic random process is formulated as a problem of optimal selection of a parametric function derived from a predetermined class of functions that satisfy the necessary and sufficient conditions of the rhythm function of a cyclic random process. …”
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Functional model of road safety for motor transport enterprise with account of high environmental temperatures by I. N. Yakunin, A. P. Fot, N. N. Yakunin, A. F. Fattakhova

“…In this regard, the study of the features of the functioning of a motor transport enterprise in conditions of high ambient temperatures and the development on this basis of a functional model for ensuring road safety is an urgent task.The purpose of this work is to improve the safety of road transport on the basis of the development of a functional structure of the road safety service of a motor transport enterprise, taking into account the high ambient temperature.Methods. …”
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Secondary metabolites of Java cardamom leaves extract function under shading and nitrogen doses by Rini A. Arista, Waras Nurcholis

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Evaluation of the renal function among sickle cell patients: a cross-sectional study by Talal Qadah, Anwar Refaei

“… This cross-sectional study aimed to explore the implications and effects of hematological and kidney function patterns in individuals with sickle cell disorder (SCD) residing in the Jazan Region of Saudi Arabia. …”
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Long term effects of physical activity types on executive functions in school aged children by Ye Tao, Yunong Zhang, Haonan Qian, Ziyi Cao

“…Executive functions were assessed using the Cambridge Neuropsychological Test Automated Battery (CANTAB), including measures of working memory, cognitive flexibility, and inhibitory control; motor competence was evaluated through a comprehensive assessment using Movement ABC-2 (assessing fine motor control), Bruininks-Oseretsky Test-2 (assessing gross motor skills), and KTK test (assessing coordination abilities), constituting a comprehensive motor development index system. …”
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Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development by Li Xu, Yuxin Cui, Jiaxin Xing, Qili Mi, Zhixing Wang, Xujing Wang, Wanli Zeng, Haiying Xiang, Jiarui Jiang, Lele Deng, Kunmiao Wang, Jiangtao Yang, Qian Gao

“…To date, although the molecular functions of genes involved in vitamin B6 biosynthesis, including Pdx1, Pdx2, Pdx3, and Sos4, have been reported in various plants, no studies have yet explored the functions of NtPDX1 and NtPDX2 in tobacco. …”
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The contrasted impacts of grasshoppers on soil microbial activities in function of primary production and herbivore diet by Ibanez, Sébastien, Foulquier, Arnaud, Brun, Charles, Colace, Marie-Pascale, Piton, Gabin, Bernard, Lionel, Gallet, Christiane, Clément, Jean-Christophe

“…This highlights the multidimensional feature of the impacts of herbivory on ecosystem functioning, both in space and time. …”
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Effects of Mulberry Leaf Extract on the Liver Function of Juvenile Spotted Sea Bass (Lateolabrax maculatus) by Sishun Zhou, Hao Lin, Lumin Kong, Jianrong Ma, Zhongying Long, Huihui Qin, Zhangfan Huang, Yi Lin, Longhui Liu, Zhongbao Li

“…In order to explore the effect of mulberry leaf extract (ELM) on the liver function of spotted sea bass, 360 fish with healthy constitution (average body weight 9.00 ± 0.02 g) were selected and randomly divided into six groups with three repetitions, and six groups of fish were randomly placed into 18 test tanks (200 L) with 20 fish per tank for the 52-day feeding test. …”
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Study on the Damage Behavior of Engineered Cementitious Composites: Experiment, Theory, and Numerical Implementation by Tingting Ding, Zhuo Wang, Yang Liu, Xinlong Wang, Tingxin Sun, Shengyou Yang

“…This study rigorously addresses this gap by initially investigating the uniaxial tensile and compressive behavior of ECCs through experiments and establishing a one-dimensional constitutive relationship of ECCs. It then introduces the concepts of damage energy release rate and energy equivalent strain, and constructs a three-dimensional constitutive model of ECCs by introducing the damage variable function. …”
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Dinamika Hubungan Antara Mahkamah Agung Dan Mahkamah Konstitusi: Perspektif Konflik Dan Kolaborasi by El Renova Ed Siregar, Adya Paramita Prabandari

“…The research results show the need to improve the working mechanisms of the Constitutional Court and Supreme Court so that they are in accordance with their respective purposes, as well as maintaining consistency in carrying out their supervisory function over the constitutionality of law. …”
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DIFFERENTIATING OF IMPLEMENTATION OF CIVIL LAW PRINCIPLES IN COURT PRACTICE by A. Y. Ryzhenkov

“…To achieve it the basic options are revealed for the application of the fundamental principles of civil legislation, and the “analogy of law” model stipulated in the RF Civil Code is criticized Methods: comparative and functional, formal-logical, documentary. Results: the author comes to the conclusion about variations in the courts application of the basic civil legislation principles. …”
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The potential of state languages of the subjects of the Russian Federation in the procedural branches of law using the example of civil proceedings by D.Kh. Valeev, A.G. Nuriev, R.V. Shakiryanov

“…Special attention has been paid to the status, role, and procedural functions of an interpreter in civil proceedings.…”
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The contributions of resting-state functional-MRI studies to our understanding of male patients with obstructive sleep apnea: a systematic review by Ruoxi Yu, Yan Li, Kangqing Zhao, Fangfang Fan

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CAR: Discovery and development by the pharmacogenetics laboratory at NIEHS, NIH by Tatsuya Sueyoshi, Masahiko Negishi

“…Within a few years, we revealed that the nuclear receptor CAR, constitutive active/androstane receptor, is the key molecule in these mechanisms. …”
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PRINCIPLE OF PROPORTIONALITY, CRITERION OF LEGITIMACY IN THE PUBLIC LAW by MARIUS ANDREESCU

“…The application and nonobservance of the principle of lawfulness in the activities of the state is a complex problem because the exercise of the state’s functions assumes the discretionary powers with which the states authorities are invested, or otherwise said the ‘right of appreciation” of the authorities regarding the moment of adopting the contents of the measures proposed. …”
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Changes in Adenylate Nucleotides Concentration and Na+, K+-ATPase Activities in Erythrocytes of Horses in Function of Breed and Sex by Maria Suska, Ewa Skotnicka

“…The aim of this study was to examine the relationships between the concentrations of ATP, ADP, AMP (HPLC methods), total nucleotide pool (TAN), adenylate energy charge (AEC) and Na+, K+-ATPase erythrocytic activities (by Choi's method) of horses as a function of breed and sex. The studies were conducted on 54 horses (stallions and mares) of different constitution types: breathing constitution (Wielkopolska and Hanoverian breed) and digestive constitution (Ardenian breed). …”
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