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2961
Metastatic Spinal Lesion with Minimal Epidural Compression: Surgical Treatment or Stereotactic Radiotherapy?
Published 2024-07-01“…+Аd.SBRT group showed an improvement in the functional status and a significantly more pronounced regression of the pain syndrome in the patients of the SBRT group, which can be explained by direct decompression of the compressed spinal root and elimination of increasing instability of the spinal column. …”
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2962
Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target.
Published 2009-11-01“…This activity was not due to a decline in the numbers or functional capacity of CD4(+)CD25(+)Foxp3(+) Tregs but rather to a major activation of 'diabetogenic' T cells. …”
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2963
STRATEGIC DIRECTIONS FOR INNOVATIVE DEVELOPMENT OF ENTERPRISE FINANCIAL-ECONOMIC SECURITY SYSTEMS BASED ON DIGITAL TECHNOLOGIES
Published 2024-12-01“…The intensification of directions for innovative development changes over time and depends on the current conditions of the enterprise's functioning. Digital technologies have transformed the situation, but the problem is whether they remain relevant over a prolonged period. …”
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2964
IgM+IgD− B cells in human gut-associated lymphoid tissue have memory features and give rise to IgM+ and IgA+ antibody-secreting cells
Published 2025-07-01“…Functionally, GALT IgM+IgD− cells spontaneously secrete IgM, and class-switch to IgA in response to both T-dependent and T-independent stimulation ex-vivo. …”
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2965
Prophylaxis of cerebro-vascular complications while performance of aorto-coronary shunting in conditions of artificial blood circulation
Published 2019-06-01“…Median age of the patients have constituted (67.3 ± 5.2) yrs old, median body mass index - (27.4 ± 5.2) kg/m2, average duration of the operation - (269.4 ± 7.8) min, including the artificial blood circulation stage - (145 ± 4.5) min. …”
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2966
Surgery of eye injuries in an eight-year period
Published 2005-01-01“…Background. Eye injuries constitute a leading problem in eye surgery worldwide, as well as at our department. …”
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2967
Learning from the process evaluation of a complex, pre-conception randomised controlled trial in Malaysia: the Jom Mama project
Published 2022-05-01“… # Methods In accordance with the realistic evaluation approach, a programme theory was developed for the Jom Mama project, based on key functions selected for six PE sub-studies, namely: recruitment; attrition; behaviour change communication (BCC); e-health (the Jom app); peer-support for community health promoters (CHPs); and contextual factors. …”
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2968
Effects of SARS-CoV-2 Spike S1 Subunit on the Interplay Between Hepatitis B and Hepatocellular Carcinoma Related Molecular Processes in Human Liver
Published 2024-12-01“…Methods: We used these proteins as seeds to extract their functional relationships from the human proteome through enrichment. …”
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2969
The wild bees (Hymenoptera, Apoidea, Anthophila) of the urban nature reserves of Rome (Italy, Latium): a preliminary survey
Published 2024-12-01“…Wild bees are amongst the most important and efficient pollinating insects and play an indispensable role in ecosystem functioning. Approximately half of the European wild bee species have been reported from Italy, making it a biodiversity hotspot for this group of insects. …”
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2970
H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation
Published 2025-05-01“…These results suggest that PRC1-mediated uH2A functions independently and cooperatively with H3K27me3 to maintain heterochromatin organization originally created by H3K9 methylation. …”
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2971
Two distinct penicillin binding proteins promote cell division in different Salmonella lifestyles
Published 2018-02-01“…This dispensability has led to the widely accepted concept of functional redundancy for many PBPs. An exemption is the PBP dedicated to build the septal PG required to separate daughter cells during cell division. …”
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2972
FEATURES OF THE IMMUNE RESPONSE TO XENOGENIC TISSUES OF VALVES AND PATCHES OF THE HEART (literature review)
Published 2019-08-01“…The highly dynamic functioning of xenogeneic biological prostheses increases their antigenicity by reducing the primary cross-linking of the extracellular matrix and activating the alternative complement pathway with adsorption on xenogeneic tissue complement component iC3b, as an opsonin for micro- and macrophages. …”
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2973
ZFAS1/STAT3 axis modulates imatinib resistance of chronic myeloid leukemia cells through glucose metabolism reprogramming
Published 2025-07-01“…This cytogenetic abnormality gives rise to the BCR::ABL1 fusion gene, which encodes the constitutively active BCR-ABL1 protein tyrosine kinase, driving uncontrolled proliferation and impaired apoptosis of hematopoietic stem and progenitor cells, leading to leukemogenesis. …”
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2974
Individual-level Predictors of Birth Preparedness and Complication Readiness: Urban–Rural Comparison
Published 2024-04-01“…Birth preparedness and complication readiness (BP/CR) constitute a veritable strategy for reducing maternal mortality, yet adoption is low with wide urban–rural discrepancies. …”
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2975
Bioinformatic exploration of RiPP biosynthetic gene clusters in lichens
Published 2025-05-01“…These BGCs are primarily involved in toxins production and defense-related functions and resulting metabolites also have a significant therapeutic potential. …”
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2976
“Ca. Nitrosocosmicus” members are the dominant archaea associated with plant rhizospheres
Published 2024-12-01“…Nitrosocosmicus” clade, which possesses functional MnKat genes unlike most other AOA, dominated the rhizosphere soils. …”
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2977
Localization and connections of the tail of caudate and caudal putamen in mouse brain
Published 2025-08-01“…These findings would offer new insights into the functional correlation and disease-related neural circuits related to the caudal striatum.…”
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2978
Metallosphaera sedula bifurcates into two sizes when it is cultured mixotrophically on soluble iron
Published 2025-05-01“…M. sedula that was cultured on yeast extract either in the absence or the presence of 20 mM soluble ferrous iron exhibited turnover numbers for soluble iron oxidation of 304 ± 26 and 333 ± 31 attamoles/cell/min, respectively. These functional data were consistent with the transcriptomic evidence presented by others, that the proteins presumably responsible for aerobic respiration on soluble iron are expressed constitutively in M. sedula. …”
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2979
Investigation of PPARβ/δ within Human Dental Pulp Cells: A Preliminary In Vitro Study
Published 2021-01-01“…However, its expression and functions are poorly understood in human dental pulp cells (hDPCs). …”
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2980
Neuromonitoring with near-infrared spectroscopy (NIRS) in aneurysmal subarachnoid haemorrhage: a systematic review protocol
Published 2020-11-01“…We will identify all observational and interventional human studies of adult patients hospitalised after aSAH that were monitored using NIRS. Functional outcome measures, including the modified Rankin Scale, the Glasgow Outcome Scale and the Barthel Index, will constitute the primary outcome. …”
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